Báo cáo y học: " Corticomotor control of the genioglossus in awake OSAS patients: a transcranial magnetic stimulation study" pdf

... upper air- way and inspiratory neuromuscular activation processes. This approach may also prove very useful to evaluate pharmaceutical treatments of the OSAS aimed at modu- lating the activity of ... that the net activity of the upper airway dila- tors is higher in awake OSAS patients than in normal indi- viduals [14,15], we hypothesized that the OSAS should be ass...

Ngày tải lên: 12/08/2014, 14:20

... ANZICS-CORE - Adult Patient Data- base [16]. All patients had initial arterial lactate and blood gas mea- sured by blood gas analyser (Rapilab, Bayer Australia, Syd- ney, NSW, Australia, upper normal limit ... hospitals comply with standards of the National Association of Testing Authorities [17] and the Royal College of Pathologists of Australasia [18]. Statistical Analysis We us...

Ngày tải lên: 13/08/2014, 20:21

... sensory information regarding eye alignment and stabilization [44]. This is an important part of the visual postural control pathway, as this pathway may compensate for visual deprivation such as in ... Okada H, Yoshikawa E, Nobezawa S, Futatsubashi M: Brain activation during maintenance of standing postures in humans. Brain 1999, 122:329-338. 89. Igarashi M, Alford BR, Watanabe T...

Ngày tải lên: 13/08/2014, 13:22

... associated, APC/ C Cdc20 is inhibited in G2 by Mad2p, a component of the spindle assembly checkpoint (SAC) pa thway [30-32] (Figure 2). In addition, activation of the DNA damage checkpoint pathway inhibits ... by the APC/C. Destruction of Pds1 (securin) by APC/C Cdc20 triggers the metaphase-anaphase transition. Checkpoint pathways monitoring spindle attachment or DNA damag...

Ngày tải lên: 13/08/2014, 18:21

... formation [4,6,7]. Phosphorylation of 4E-BP1 is blocked by rapamy- cin, which inhibits the mTOR (mammalian target of rapamycin) signalling pathway (see accompanying review by Proud [1]). Rapamycin ... proliferative stimuli or to cytokines, the types of stimuli that activate the Erk and/or p38 MAP kinase pathways. On the other hand, insulin, as an anabolic stimulus, may largely i...

Ngày tải lên: 23/03/2014, 21:20

... and 30 days after antibody transfer. Histologically, analysis of joints 30 days after transfer revealed less inflammation than in the K/B×N model itself, and little cartilage damage, supporting ... to the disease itself [30]. Thus, the presence of these autoantibodies in RA, often preceding disease by many years, may indicate a breakdown in central and/or peripheral toleranc...

Ngày tải lên: 09/08/2014, 10:20

... A, Yamada R, Chang X, Tokuhiro S, Sawada T, Suzuki M, Nagasaki M, Nakayama-Hamada M, Kawaida R, Ono M, et al.: Functional haplotypes of PADI4, encoding citrullinating enzyme peptidylarginine ... beta may play a role in the maintaining DC in an immature state or in the upregulation of CD 1a expression [97]. DC and macrophages contribute very early in the develop- ment of...

Ngày tải lên: 09/08/2014, 10:20

... [30,31], suggesting that the chondrocyte may also participate in degrading its own matrix by releasing autocrine–paracrine factors. Of the matrix metalloproteinases (MMPs) involved in the degradation of cartilage ... cartilage surface at the cartilage– pannus junction and is upregulated by inflammatory cytokines [55]. Among the known cathepsins, cathepsin K is the only pro...

Ngày tải lên: 09/08/2014, 10:21

... 7:R370-R379. 32. Kawane K, Ohtani M, Miwa K, Kizawa T, Kanbara Y, Yoshioka Y, Yoshikawa H, Nagata S: Chronic polyarthritis caused by mam- malian DNA that escapes from degradation in macrophages. Nature 2006, ... following common inflammatory stimuli and displays a variety of pro- and anti-inflammatory properties [66]. In support of a pro-inflammatory role in arthritis, neutra...

Ngày tải lên: 09/08/2014, 10:22

Ngày tải lên: 09/08/2014, 10:22