Báo cáo y học: " Mitogen-activated protein kinases and NFκB are involved in SP-A-enhanced responses of macrophages to " pdf
... SD. Results Herbimycin A inhibits nitric oxide production induced by BCG and SP-A-BCG complexes Activation of intracellular protein tyrosine kinases is a common pathway involved in signalling induced by a variety ... purposes) inflammatory mediators by rat macrophages in response to BCG through increased activation of intra-macrophage signalling pathways involving MAP ki...
Ngày tải lên: 12/08/2014, 14:20
... combinations of these cytokines. Immunofluorescence staining Immunofluorescence staining was performed on control and stimulated rheumatoid synoviocytes (i.e. before and 30 min after cytokine ... tumor necrosis factor alpha (TNF-α) and IL-1 inhibitors strongly support the importance of cytokines in RA. These cytokines are key activators of the TFs AP-1, Egr-1 and NF-κB. Bind...
Ngày tải lên: 09/08/2014, 01:23
... neutrophil infiltration into the lungs and to increased pulmonary proinflammatory cytokine expression [7]. However, the initial events induced by hyperoxia, thereby leading to acute inflammatory lung injury, ... leads to increasing intracellular stores of GSSG, a potent inhibitor of NF-κB transcription factor DNA binding. The pathway leading to the formation of GSH by the acti...
Ngày tải lên: 12/08/2014, 19:21
Báo cáo y học: "Science review: Redox and oxygen-sensitive transcription factors in the regulation of oxidant-mediated lung injury: α role for hypoxia-inducible factor-1α" pptx
... lung injury, ischemia-reperfusion and transplantation, compromised host defense and inflammatory stimuli, and hypoxemia and the crucial role of hypoxia-inducible factor in mediating lung injury. ... 28:920-925. 41. Haddad JJ: Oxygen-sensitive pro-inflammatory cytokines, apoptosis signaling and redox-responsive transcription factors in development and pathophysiology. Cytokin...
Ngày tải lên: 12/08/2014, 19:21
Báo cáo y học: " Interactions Between Estrogen- and Ah-Receptor Signalling Pathways in Primary Culture of Salmon Hepatocytes Exposed to Nonylphenol and 3,3'''',4,4''''-Tetrachlorobiphenyl (Congener 77)" ppsx
... expression patterns of ERα (A), ERβ (B), Vtg (C) and Zr -protein (D) mRNA in primary cul- ture of salmon hepatocytes exposed to 5 μM NP and 1 μM PCB-77, both singly and in combination. Hepatocytes were ... domains, the N-terminal bHLH and the PAS domain [2,3]. Cytochrome (CYP) P450 enzymes (CYP1A1, 1A2, 1B1) are involved in the metabolism of a wide variety of str...
Ngày tải lên: 13/08/2014, 13:20
Báo cáo y học: " Possible Cis-acting signal that could be involved in the localization of different mRNAs in neuronal axons" potx
... likely that β-actin and tropomyosin are not exclusive to the axon and could be also found in dendrites. Cofilin is a cytoskeleton modulating protein; it is also known as actin depolymerizing factor ... S, Shenoy SM, Hartley A, Stanton PK, Singer R, Bassell GJ: Activity-Dependent Trafficking and Dynamic Localization of Zipcode Binding Protein 1 and β- Actin mRNA in Dendrit...
Ngày tải lên: 13/08/2014, 23:20
Báo cáo y học: " Perceived protein needs and measured protein intake in collegiate male athletes: an observational study" potx
... Protein Intake. The RDI, maximum beneficial level of protein intake, and the mean actual protein intake as determined by 3-day food record analysis in grams of protein per kg of body weight per day. 30 40 50 60 70 % of EnergyIntake RecommendedIntake ActualIntake p=0.006 p020 p=0.05 10 20 30 40 50 60 70 Carbohydrate ... perception of protein needs by as king the su...
Ngày tải lên: 11/08/2014, 23:21
báo cáo hóa học: " Hypoxia-inducible factor-1 (HIF-1) is involved in the regulation of hypoxia-stimulated expression of monocyte chemoattractant protein-1 (MCP-1/CCL2) and MCP-5 (Ccl12) in astrocytes" pdf
... transcriptional up-regulation of inflammatory cytokines and chemokines during hypoxia; whereas NFκB is mainly involved in transcriptional regu- lation of these genes during the phase of reoxygenation [8,40]. ... and infiltration of inflammatory cells in focal brain ischemia of hypertensive rats [38]. Astrocytes are main cytokine/ chemokine-producing cells in the brai...
Ngày tải lên: 19/06/2014, 22:20
Báo cáo y học: "Caveolin-1 expression and stress-induced premature senescence in human intervertebral disc degeneration" docx
... proposed to mediate SIPS in murine fibrob- lasts and human articular chondrocytes in response to oxidative stress and the inflammatory cytokine interleukin-1β (IL-1β) (both of which are known to be increased ... Christine Lyn Le Maitre 2 and Judith Alison Hoyland 1 1 Tissue Injury and Repair Group, Research School of Clinical and Laboratory Sciences, Faculty of Me...
Ngày tải lên: 09/08/2014, 10:23
Báo cáo y học: "Pu-Erh tea and GABA attenuates oxidative stress in kainic acid-induced status epilepticu" docx
... expression of heat shock protein HSP-70 mRNA, brain-derived neurotrophic factor mRNA, and cyclooxygenase-2 mRNA in rat brain following seizures induced by systemic administration of kainic acid. Brain ... showing suppression of ROS and Ca 2+ release by PETL are con- sistent with the proposed role of GABA and PETL extract in neuronal protection. Cytokines and chemokines...
Ngày tải lên: 10/08/2014, 10:20