tried and true tactics are valued in the allocation of budgets
Báo cáo khoa học: The starch-binding capacity of the noncatalytic SBD2 region and the interaction between the N- and C-terminal domains are involved in the modulation of the activity of starch synthase III fromArabidopsis thaliana pdf
... interaction between the N- and C-terminal domains of SSIII in vitro Mapping of the CD-binding region in the N-terminal SBDs In order to identify the SBD region required for the SBD–CD interaction, we ... in the D2 domain and D(495–535) in the D3 domain This result is in agreement with our previous studies using truncated SSIII isoforms, showing the importance of the D23 domain in starch binding ... These data are in agreement with the pull-down and far western assays, showing a lack of interaction for the individual SBDs and also in the absence of the D(316–344) and D(495–535) regions of...
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Báo cáo y học: "Reduced proportions of natural killer T cells are present in the relatives of lupus patients and are associated with autoimmunity" ppt
... frequency of 23.9% in the mothers (P < 0.001), 22.4% in the fathers (P < 0.001), and 16% in the siblings (P = 0.008) Comparison of cellular phenotypes between ANA+ and ANA- relatives using the van ... obtained by random digit dialing, which permitted general matching for geographic area Additional control individuals matching the age distribution of the parents of the lupus patients were obtained ... heritable trait These findings raise the possibility that one of the explanations for the clustering of multiple autoimmune disorders within the families of lupus patients is the presence of genetic...
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Báo cáo y học: "B-lymphocyte stimulator/a proliferation-inducing ligand heterotrimers are elevated in the sera of patients with autoimmune disease and are neutralized by atacicept and B-cell maturation antigen-immunoglobulin" pdf
... role in regulating diverse aspects of immune function, including mediating inflammatory responses and facilitating adaptive immunity [9-11] The binding of BLyS and APRIL to TACI, BCMA, and BAFF-R ... form of BLyS The molecular mass of the heterotrimers was confirmed by SEC-MALS mass distribution LS/UV/RI 3-detector analysis Binding kinetics and affinity studies The binding affinities and kinetics ... oligomerization of the ligands in this study (data not shown) The inhibition of BLyS, APRIL, and the heterotrimers by atacicept is consistent with the observed effects of atacicept and/ or murine TACI-Ig in...
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Tài liệu Báo cáo Y học: The b-1,4-endogalactanase A gene from Aspergillus niger is specifically induced on arabinose and galacturonic acid and plays an important role in the degradation of pectic hairy regions pdf
... stranded sequence was determined for a region of this construct containing galA and some of the flanking regions, resulting in the genomic sequence of A niger galA The presence of one putative intron ... control of the xylanolytic activator protein [32,41] The increase in expression levels of galA in the CREA mutant, indicates that at least one of the detected putative CREA binding sites in the promoter ... proteins The three arabinogalactans were incubated with GALA for 15 min, 30 min, h and 20 h to determine the substrate specificity of the enzyme The degradation of the polymer Ó FEBS 2002 and subsequent...
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Đề tài " Axiom A maps are dense in the space of unimodal maps in the Ck topology " doc
... intersection of two disks of the same radius in such a way that two points of the intersection of the boundaries of these disks are joined by I and the angle of this intersection at these points ... below in Appendix 5.2 (Lemma 5.2) Thus, the combination of Lemma 2.4 in [dFdM], the results of [Koz] and of the proof of the renormalization theorem in [LvS] provides Theorem 2.3 The outline of the ... At the point a the λ λ boundaries of the domains B and A are tangent to each other, and if the multiplier dλ changes with λ, then the derivative of h0 in the direction of λ ∂A is and in the...
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Báo cáo khoa học: "COMMON TOPICS AND COHERENT SITUATIONS: INTERPRETING ELLIPSIS IN THE CONTEXT OF DISCOURSE INFERENCE" ppt
... way of their corresponding node(s) in the syntax; the operations performed on these representations are dictated by the nature of the constraints imposed The two types of inference are distinguished ... elliptical and event referential forms as to whether they leave behind an empty constituent in the syntax and whether they are anaphoric in the semantics Empty constituents in the syntax are not in themselves ... Understanding segments of utterances standing in a Common Topic relation requires the determination of points of commonality (parallelism) and departure (contrast) between sets of corresponding...
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BRANDS ARE BUILT IN THE CONSCIOUSNESS OF THE RECEIVER, NOT BY THE COMPANY potx
... trend in branding outside the traditional marketing arena – companies’ investments in sustainability for the environment and in the social arena “If brands have a personality, then more and more ... polish their brand “Brand building is more interesting in an economic downturn because media budgets are being tightened,” he says “Marketers are forced to abandon their tried and true strategies and ... water and energy?” and “How can we reduce the amount of garbage?” are often asked The expression “minimizing waste” is governing many trends, in each phase of the chain Customers, who are becoming...
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Trends of Health Education in the Developed Countries and Recommendations for Health Education in the Kingdom Of Saudi Arabia potx
... genetic indicators of the appropriateness of drugs d Rehabilitation, and care within institutions and the community e Relieving pain and distress f Palliative care, including care of the terminally ... bridged to the bachelor program and giving them the opportunity for career promotion, and consequently increasing the enrollment rate in the nursing profession and increasing the number of nurses ... levels are the university nursing education and the proper training of nursing students However, the previous and the ongoing developments in the medical and health fields, and the multitude of variables...
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Báo cáo khoa học: Huntington’s disease: roles of huntingtin-interacting protein 1 (HIP-1) and its molecular partner HIPPI in the regulation of apoptosis and transcription pptx
... the amount of the interacting proteins but also on the affinities of interacting proteins The uncreased expression of caspase-1 observed in HD may be mediated through HIPPI The role of HIP-1 in ... Conclusions HIP-1 and its interacting partner HIPPI together induce apoptosis by the intrinsic and extrinsic pathways Homer 1c, an interactor of HIPPI, and the wild-type N-terminal Htt, which interacts ... [29] The ANTH ⁄ ENTH domain of HIP-1 interacts with 3-phosphate containing inositol lipids and stabilizes the growth factor receptor tyrosine kinases by increasing their half-life following ligand...
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Báo cáo khoa học: Upstream and intronic regulatory sequences interact in the activation of the glutamine synthetase promoter pot
... of the rst intron of GS The nucleotide sequences of the upstream region and of the rst 1938 nucleotides of the rst intron of the rat GS gene were reported [5,6] This intron sequence ends at the ... sequences present in the respective constructs are shown in the left portion of the gure as solid black lines The upper line shows the linkage of the 5.3-kb genomic GS segment with the luciferase ... activities of combinations of upstream enhancer and the entire upstream region, respectively, in conjunction with the minimal promoter, the minimized rst intron and the respective intron elements...
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Báo cáo khoa học: Inactive forms of the catalytic subunit of protein kinase A are expressed in the brain of higher primates potx
... present in brain, but not in PBL (Fig 3A, lanes and 3) To examine whether the CbD4 variants were expressed in different parts of the brain as well as in fetal brain, PCR was carried out using the ... DC305863 and DC310086) and several of the CbD4 variants contained sequences encoded by the exons a, b and c in the Cb gene that are only transcribed in nerve cells [6] In addition, the brain is the ... against kemptide using c-[32P]ATP and increasing concentrations of cAMP Relative increase in kinase activities were compared to PKA activity in mock transfected cells and are presented as the...
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Báo cáo khoa học: " A phase III trial comparing an anionic phospholipid-based cream and aloe vera-based gel in the prevention of radiation dermatitis in pediatric patients" pdf
... applied topically and liberally to the affected area with the bare hand Application of the cream was accomplished with the ventral surface of the fingers using a rotary motion of the fingers with light ... administered in the same manner and on the skin of the same patient, we removed the individual effects by analyzing the difference of the two scores (i.e., gel score – cream score) rather than the ... Both molecules are polar and water seeking; therefore, they are attracted to the water layers of the stratum corneum, other layers of the epidermis, and the underlying dermis, depending on http://www.ro-journal.com/content/2/1/45...
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Báo cáo y học: "Indoleamine 2,3-dioxygenase-expressing dendritic cells are involved in the generation of CD4+CD25+ regulatory T cells in Peyer''''s patches in an orally tolerized, collagen-induced arthritis mouse model" ppt
... tolerance and immune inhibition in the induction of oral tolerance in the murine CIA model We examined the change in the expression of IDO in CD11c+ DCs of Peyer's patches after repeated oral administration ... erythema from the ankle to the tarsal bone, = moderate edema and erythema from the ankle to the tarsal bone, and = edema and erythema from the ankle to the entire leg The sum of the values from ... be interesting to investigate IDO expression in different subsets of DCs from tolerized mice and to characterize their role in the induction and maintenance of immune tolerance Available online...
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Báo cáo y học: "Treatment of hypertriglyceridemia and HIV: fenofibrate-induced changes in the expression of chemokine genes in circulating leukocytes" ppsx
... wrote the first draft of the manuscript JJ, JC and JMA contributed to the final version of the manuscript GA, RB-D and AR helped in the data analysis and interpretation JJ and JC supervised the ... changes in the pattern of chemokine gene expression in circulating leukocytes The data suggest that PPARα activators may be useful in the attempt to decrease the risk of atherosclerosis and may ... AM, Voltarelli JC, Morimoto HK, Watanabe MA: Genetic polymorphisms in the chemokine and chemokine receptors: impact on clinical course and therapy of the human immunodeficiency virus type infection...
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Báo cáo y học: "Rho kinase inhibitors Y27632 and H1152 augment neurite extension in the presence of cultured Schwann cells" pdf
... fusion toxin (C3 FT), a chimeric protein consisting of the Clostridium limosum toxin C3 and the N-terminal adaptor domain of Clostridium botulinum C2I, which interacts with the binding/transport ... promoting the stabilisation of the growth cone and thus, shifting the balance in the dynamics of growth cones in favour of axonal elongation Further work using an in vivo model is warranted to gain ... These were surplus animals from the animal breeding program belonging to the Faculty of Veterinary Science of the University of Freiburg The animals were housed and handled in accordance to the...
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báo cáo khoa học: " Use of the evidence base in substance abuse treatment programs for American Indians and Alaska natives: pursuing quality in the crucible of practice and policy" ppsx
... National Institute of Alcohol Abuse and Alcoholism to the IHS in 1978 [59], and the training of counselors for these programs was (and is) often done through special training programs (e.g., the Southwest ... with the successful dissemination of innovations into clinical practice These factors were subsequently highlighted in the Institute of Medicine’s report ‘Improving the Quality of Health Care ... hypothesize they are having on the use of EBTs in these substance abuse programs The most relevant factors are discussed below and summarized in Table Discussion of specific concerns regarding the...
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Báo cáo y học: "Cigarette Smoke Exposure Alters mSin3a and Mi-2α/β Expression; implications in the control of pro-inflammatory gene transcription and glucocorticoid function" ppt
... either the composition or the stepwise construction and targeting of the mSin3a and Mi-2 co-repressor complexes or their role in disease The reduction in mSin3a expression in the lungs of cigarette ... alteration of both the formation and targeting of these complexes Consequently, an oxidant-mediated reduction in the protein expression of Mi-2α and mSin3a and increased protein expression of Mi2β may ... expression of both Mi-2α/β and mSin3a co-repressors are altered in the lungs of mice exposed to cigarette smoke These data are consistent with the effect of cigarette smoke on other co-repressor and...
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Báo cáo y học: "Cigarette Smoke Exposure Alters mSin3a and Mi-2α/β Expression; implications in the control of pro-inflammatory gene transcription and glucocorticoid function" pdf
... either the composition or the stepwise construction and targeting of the mSin3a and Mi-2 co-repressor complexes or their role in disease The reduction in mSin3a expression in the lungs of cigarette ... alteration of both the formation and targeting of these complexes Consequently, an oxidant-mediated reduction in the protein expression of Mi-2α and mSin3a and increased protein expression of Mi2β may ... expression of both Mi-2α/β and mSin3a co-repressors are altered in the lungs of mice exposed to cigarette smoke These data are consistent with the effect of cigarette smoke on other co-repressor and...
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Báo cáo y học: "Science review: Redox and oxygen-sensitive transcription factors in the regulation of oxidant-mediated lung injury: κ role for nuclear factor-κ" pdf
... the iNOS inhibitor N6-(iminoethyl)-L-lysine or using iNOS knockout mice that the activation of NF-κB and the signal transducer and activator of transcription, and that increases in IL-6 and granulocyte ... to increasing intracellular stores of GSSG, a potent inhibitor of NF-κB transcription factor DNA binding The pathway leading to the formation of GSH by the action of γ-glutamylcysteine synthetase ... is interesting to observe that IL-11 did not affect the BALF content of the CXC chemokines, of the macrophage inflammatory protein-2 and of the cytokine-inducible neutrophil chemoattractant The...
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Báo cáo y học: "Science review: Redox and oxygen-sensitive transcription factors in the regulation of oxidant-mediated lung injury: α role for hypoxia-inducible factor-1α" pptx
... to the VEGF gene, Hellwig-Bürgel et al investigated the effects of these cytokines on the activation of the HIF-1 DNA-binding complex and the amount of HIF-1α protein in human hepatoma cells in ... Targeting the NF-κB pathway may therefore be a promising therapy to reduce injury and to improve lung function play a central role in initiating the innate immune system and in activating NF-κB ... synthase and production of prostaglandins [53] Induction of inducible nitric oxide synthase during the ischemic phase of HS may involve the activation of HIF-1 Increased expression of cyclooxygenase-2...
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Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản khảo sát chương trình đào tạo gắn với các giáo trình cụ thể xác định thời lượng học về mặt lí thuyết và thực tế điều tra đối với đối tượng giảng viên và đối tượng quản lí khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ rôto dây quấn các đặc tính của động cơ điện không đồng bộ hệ số công suất cosp fi p2 đặc tuyến tốc độ rôto n fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha sự cần thiết phải đầu tư xây dựng nhà máy thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008 chỉ tiêu chất lượng 9 tr 25