Báo cáo y học: " Effects of PPARg ligands on TGF-b1-induced epithelial-mesenchymal transition in alveolar epithelial cells" ppsx

... partial inhibitory effects of both PPARg ligands (Figure 3C, D, E). Thiazolidinediones inhibit TGF-b1-induced changes in N-cadherin expression independent of PPARg Low basal expression of N-cadherin ... the context of the effects of RGZ and CGZ on changes in expression of phenotypic markers of EMT. Conclusion In the current study, treatment with PPARg liga...

Ngày tải lên: 12/08/2014, 11:20

... nitrite concentration and iNOS expression in a murine lung epithelial cell line in vitro[37]. In contrast, Comhair et al showed no change in iNOS expression in airway cells from healthy subjects ... mM NAC on 0.5 % CSS-induced inhibition of degranulation of RBL-2H3 cellsFigure 6 Effects of 1 mM NAC on 0.5 % CSS-induced inhibition of degranulation of RBL-2H3 cells....

Ngày tải lên: 12/08/2014, 18:22

... glycosi- dases found in diseased synovium [13]. The decrease in molecular size, in combination with dilution from inflammatory infiltration of plasma fluid and proteins in aberrant joint condi- tions, ... [15]. Numerous in vitro investigations have reported the efficacy of exogenous HA in modulating acute and chronic inflammation, either by reducing cellular interactions [16],...

Ngày tải lên: 09/08/2014, 08:23

... act directly on the hydrolysis of adenine nucleotides only during the night period in rats (day in humans) where there is a significant physiological increase of NTPDase 1 activity, suggesting a possible ... hydrolysis. For all enzyme assays, incubation times, substrate and protein concentrations were chosen in order to ensure the linear- ity of the reactions. All samples were r...

Ngày tải lên: 10/08/2014, 09:20

... myocardium by up- regulating the expression of Cx43. Keywords: Cardioelectrial activity Connexin43, Ischemic preconditioning, Myocardial hypertrophy Background Various degrees of myocardial injury ... validating an animal model: (1) a 20% increase in myocardial weight and thickness, (2) Hematoxylin and Eosin (H&E) staining outlining hypertrophic myocyte morphology and alteration of...

Ngày tải lên: 10/08/2014, 09:21

... regulation of inflammatory responses mediated by NaHS in pancreas and lung. Conclusions In conclusion in this study of acute pancreatitis induced by hourly caerulein administration, pretreatment by ... hydrosulfide; MPO: Myeloperoxidase; CBS: Cystathionine β-synthetase; CSE: Cystathionine γ-lyase; PAG: DL-propargylglycine; TMB: tetramethylbenzidine; ELISA: Enzyme-linked immunosorben...

Ngày tải lên: 11/08/2014, 08:22

... median and interquartile range * p < 0.05 ‡ p ≤ 0.01 Morphometry of pulmonary arteryFigure 2 Morphometry of pulmonary artery. Hematoxylin-eosin stained sections of main pulmonary artery (upper ... smoking may contribute to pulmonary hypertension in chronic obstructive pulmonary disease by altering the structure and function of pulmonary vessels at early disease stages. The obje...

Ngày tải lên: 12/08/2014, 14:20

... No Yes Yes Yes Yes Yes 8 Brosseau, et al. [24] Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes 10 Stange- Rezende, et al. [35] Yes No Yes No No Yes No Yes Yes Yes 6 Favaro, et al. [39] No No Yes Yes ... No Yes No Yes Yes 5 Stamm, et al. [34] Yes No Yes No No Yes Yes No Yes Yes 6 Lefler and Armstrong [30] Yes No Yes No No No Yes No Yes Yes 5 Rogers and Wilder [33] Yes No Yes Yes No No No No Yes ... at...

Ngày tải lên: 12/08/2014, 15:22

... ciliary beating or coughing. The efficiency of the mucociliary system depends not only on the integrity of the epithelium and on ciliary activity but also on the amount of mucus, the depth of the ... improve ventilatory support in respiratory failure, it is generally known that this procedure markedly increases the incidence of pul- monary infection and consequently the morb...

Ngày tải lên: 12/08/2014, 18:21

... Barnes S: Gaining insight into the health effects of soy but a long way still to go: commentary on the fourth International Symposium on the Role of Soy in Pre- venting and Treating Chronic Disease. ... * Testosterone nmol/l Effects of phytoestrogens on plasma total triiodothyronine (T 3 ) concentrations in male goat kidsFigure 2 Effects of phytoestrogens on plasma...

Ngày tải lên: 12/08/2014, 18:22