báo cáo khoa học: " Transcriptome changes in the phenylpropanoid pathway of Glycine max in response to Pseudomonas syringae infection" ppsx

Tài liệu Báo cáo khoa học: Diversity and junction residues as hotspots of binding energy in an antibody neutralizing the dengue virus doc

... alanine scanning of the L-CDR3 and H-CDR3 loops of antibody mAb4E11.This scanning allowed us to identify the residues of these loops that contributed to the energetics and kinet-ics of the interaction ... mAb4E11 and its antigen.It showed that the residues of diversity, H-Trp96 and H-Glu97, and the residues of junction, L-Trp96,H-Gly95 and H-Gly98, constituted major hotspots of binding energy. ... VLcontain the residues of diversity and junction, encoded by the D segment, and the VH-D, D-JH, and VL-JLjunctions [17]. They are located at the center of the antibody combining site...

Báo cáo khoa học: A single EF-hand isolated from STIM1 forms dimer in the absence and presence of Ca2+ ppt

... that the isolated canonical EF-hand alone has an intrinsic tendency toform a dimer, which is in agreement with the EF-hand pairing paradigm. Clearly, the canonical EF-hand motif alone is able ... engineeredprotein CD2 .STIM1. EF increased, indicating that the inserted EF-hand motif at least partially maintains the natural helical structure after grafting. The Ca2+dis-sociation constant of CD2 .STIM1. EF ... ‘punctae’ and aggregates near the plasma membrane [1,6]. The N-terminal region of STIM1 contains a canonical EF-hand motif and a pre-dicted SAM domain. Stathopulos et al. [23,24] isolated the...

Báo cáo khoa học: "Exploring and Exploiting the Limited Utility of Captions in Recognizing Intention in Information Graphics∗" pdf

... Meeting of the ACL, pages 223–230,Ann Arbor, June 2005.c2005 Association for Computational LinguisticsExploring and Exploiting the Limited Utility of Captions in Recognizing Intention in Information ... particularly interested in whether shallow processing of captions can con-tribute to recognizing the intended message of an information graphic. As mentioned earlier, the in- tended message of each information ... captions are often very general. The objective of their corpus study was to categorize the kinds of information in captions so that their ﬁnd-ings could be used in forming rules for generatinggraphics...

Báo cáo khoa học: Novel diadenosine polyphosphate analogs with oxymethylene bridges replacing oxygen in the polyphosphate chain pdf

... al. Oxymethylene diadenosine polyphosphate analogs FEBS Journal 276 (2009) 15461553 ê 2009 The Authors Journal compilation ê 2009 FEBS 1551 Novel diadenosine polyphosphate analogs with oxymethylene ... tounderstand their biological functions has been through the use of NpnNÂ analogs. Here, we present the results of studies using novel diadenosine polyphosphate analogs, with an oxymethylene group replacing ... cleavage ofdinucleoside polyphosphate molecules modiﬁed in theirADP moieties. In addition, none of the oxymethylene analogs investigated inhibited the hydrolysis of Ap4Acatalyzed by the E. coli...

Báo cáo khoa học: Kinetic studies and molecular modelling attribute a crucial role in the speciﬁcity and stereoselectivity of penicillin acylase to the pair ArgA145-ArgB263 pdf

... Kinetic studies and molecular modelling attribute a crucial role in the speciﬁcity and stereoselectivity of penicillin acylase to the pair ArgA145-ArgB263 Maya Guncheva1, Ivaylo Ivanov2, ... atoms of the main chain CO groups of LeuB387 and TrpB240, Od1atom of AsnB241, and Oc atom of SerB386 and is expected to stabilize the positive charge of ArgB263.All of these views remain arguable, ... of some arylamide substrates docked in the active site of penicillin acylase by AM1 calculations. Amino acid residues of the enzyme are at their X-ray coordinates [19]. Substrates having local...

Báo cáo khoa học: NrpRII mediates contacts between NrpRI and general transcription factors in the archaeon ¨ Methanosarcina mazei Go1 pot

... to the NrpRI ⁄ NrpRII complex decreases the binding afﬁnity of NrpRI to the operator as well asdecreasing the NrpRII binding afﬁnity to the general transcription factors, potentially by inducing ... studied the binding properties of NrpRII to the general transcription factors – TATA-binding protein(TBP) and the archaeal homolog of the eukaryotic general transcription factor TFIIB (TFB). MBP– NrpRII, ... Consequently, potential formation of a complex between NrpRI and NrpRII, as well as between NrpRII and general transcription factors, were investigated and the effects of 2-oxoglutarate on binding were...

Báo cáo khoa học: Relaxin-3⁄ insulin-like peptide 7, a neuropeptide involved in the stress response and food intake Masaki Tanaka pptx

... FEBS 4993 MINIREVIEWRelaxin-3⁄ insulin-like peptide 7, a neuropeptide involved in the stress response and food intake Masaki Tanaka Department of Basic Geriatrics, Kyoto Prefectural University ... Relaxin-3 is so named because it has a motif thatcan interact with the relaxin receptor. By contrast to other relaxins,relaxin-3 is mainly expressed in the brain and testis. In rodent brain, ana-tomical ... administeredrelaxin-3 induces Fos expression in the osmosensitiveareas in rat brain and facilitates water intake. Peptides31, 1124–1130.36 Shiba K, Kageyama H, Takenoya F & Shioda S (2010)Galanin-like...

báo cáo sinh học:" Employment and sociodemographic characteristics: a study of increasing precarity in the health districts of Belo Horizonte, Brazil" pdf

... for Health Open AccessResearch Employment and sociodemographic characteristics: a study of increasing precarity in the health districts of Belo Horizonte, BrazilMaria Cristina Ramos de Vasconcellos ... competing interests.Authors' contributionsMC, AA and SB jointly formulated the study design. MCobtained the data. MC and AA were involved in the con-ceptualization, initial drafts and final ... gratefully acknowledge the assistance of Dra. Ana Flavia Mach-ado, Professor of Demography at the University of Minas Gerais, in analysis of the data and for her helpful comments and editing.This...

Báo cáo khoa học " Lentinula edodes enhances the biocontrol activity of Cryptococcus laurentii against Penicillium expansum contamination and patulin production in apple fruits " ppt

... investigate the in uence of L. edodes extracts on the control activity of C. laurentii against P. expansum contamination and patulin biosynthesis in apple fruits in order toimprove the biocontrol activity ... biocontrol agent, sincethey promote a signiﬁcant delay in the conidia germination of the pathogen P. expansum and an inhibition of patulin production. Nevertheless, the performance of LF23 in ... C. laurentii improved the efﬁciency of the biocontrol activity of the yeast leading to an almost total control of P. expansum growth and patulin production and promoting asigniﬁcant increase of...

Báo cáo khoa học: "A study on the immunocytochemical localization of neurofascin in rat sciatic nerve" doc

... interesting to reveal the presence of incisures during the earliest stages of myelination and the initial expression of neurofascin in the incisure. The cytoplasmic domains of neurofascin contain ... the exact localization of neurofascin in the peripheral nerves is important to clarify the function of thismolecule. In this report we have examined the ultrastructural localization of neurofascin ... recognizing the axons that they ensheath during the development. In the CNS, neurofascin is strongly but transiently up-regulated in oligodendrocytes at the onset of myelinogenesis. After the initial...

Báo cáo khoa học: "Collaborative control initiatives targeting zoonotic agents of alveolar echinococcosis in the northern hemisphere" ppsx

... because of the cost of the drug, the replacement of sled-dogs by machines decreased remarkably the incidence of alveolar echinococcosis in the island. However, with the presence of other definitive ... Taken together, these findings indicate that invasion of young infected foxes into the territories left by the hunted foxes could maintain or increase the preva-lence rate of infection. In Japan, ... mkamiya@rakuno.ac.jpCollaborative control initiatives targeting zoonotic agents of alveolar echinococcosis in the northern hemisphereMasao Kamiya*OIE Reference Laboratory for Echinococcosis and Laboratory of Environmental...

Báo cáo khoa học: "general overview with a seasonal assessment silver fir forest in the Vosges mountains (France)" docx

... class="bi x0 y0 w1 h0" alt="" Review articleAluminium toxicity in declining forests: a general overview with a seasonal assessment in a silver fir forest in the Vosges mountains ... performant Ca/Al ratio and is used in a declining fir stand in the Vosges mountains (eastern France). A potential Al toxicity phase was observed in winter only, namely during ... with reasonable as-sumptions.APPLICATION: A CASE STUDY IN A DECLINING SILVER FIR FOREST IN THE VOSGES MOUNTAINS (NORTH-EASTERN FRANCE)To illustrate the previous considerations,we...

báo cáo khoa học: "Transcriptome analysis by GeneTrail revealed regulation of functional categories in response to alterations of iron homeostasis in Arabidopsis thaliana" pdf

... 11:87http://www.biomedcentral.com/1471-2229/11/87Page 5 of 10 METH O D O LOG Y AR T I C LE Open AccessTranscriptome analysis by GeneTrail revealed regulation of functional categories in response to alterations of iron homeostasis in Arabidopsis thalianaMara ... be incorpo-rated into the GSEA tool of GeneTrail as individuallydefined categories. Contrary to the GeneTrail- predefined categories the genes of MapMan categories had beengrouped according to ... theweb-based software NIA Array Analysis tool developed by the National Institute on Aging [21] was utilized.The statistical analysis performed with this online toolwas based on the single-factor ANalysis...

báo cáo khoa học: " Transcriptome changes in the phenylpropanoid pathway of Glycine max in response to Pseudomonas syringae infection" ppsx

... pathway in response to Psginfection. All together, the resulting transcript profilesobtained have shown that lignin/suberin biosyntheisappears to be the first response of the pathway in the infected ... genes downstream of F3H, thus givingpreference to the isoflavone/phytoalexin branch of the pathway during the response to infection. The criticalnature of partitioning the naringenin substrate ... compartmental-ized expression of the isoflavonoid pathway leading to the synthesis of isoflavones in the roots and cotyledons andan inducible isoflavonoid-phytoalexins synthesis in the leaves of pathogen stressed...

Báo cáo khoa học: " Ruminal acidosis and the rapid onset of ruminal parakeratosis in a mature dairy cow: a case report" doc

... adaptsduring the initial stage of ruminal acidosis in a mature dairy cow. In this study, the acute form of ruminal acido-sis (ruminal pH < 5.0) was induced rapidly and the fourstrata of the ... for acute ruminal acidosis. BioMed CentralPage 1 of 6(page number not for citation purposes)Acta Veterinaria ScandinavicaOpen Access Case report Ruminal acidosis and the rapid onset of ruminal ... morphological, and functional adaptations in the rumen mucosa observed in a cow during the early stages of a grain-induced ruminal acidosis. Case presentation A 10-year old, non-lactating Holstein dairy...

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