... Access Research Replication and drug resistant mutation of HIV-1 subtype B' (Thailand B) variants isolated from HAART treatment individuals in China Jianping Sun 1,2 , Liying Ma* 1 , Xiaoling Yu 1,3 , ... more and more in AIDS individuals with highly active antiretroviral therapy (HAART) treatment. Understanding the replication and drug resis...
Ngày tải lên: 12/08/2014, 04:20
... United Nations Office on Drug and Crimes (UNODC) and the Ministry of Health of Iran in 2003 [4]. As a part of this outreach program, distribution and exchange of needles and syringes have been ... estimated length of contact, and the total number of syringes they received from the program. Of 131 male injecting drug users who ever received free needles/syringes...
Ngày tải lên: 11/08/2014, 20:20
Tài liệu Báo cáo khoa học: Molecular and cellular specificity of post-translational aminoacyl isomerization in the crustacean hyperglycaemic hormone family docx
... (G) Sinus gland axonal arborizations containing D-Trp4 VIH (green) and D-Phe3 CHH (red). (H) Enlargement of axon terminals in the sinus gland with labelling as in (G). Peptidyl isomerization in ... (made in rat) and gp-anti-dW4 (produced in guinea pig), two antisera discriminating CHH isomers (gp-anti-pQl made in guinea pig and rb-anti- pQd in rabbit) [38] and an antis...
Ngày tải lên: 18/02/2014, 11:20
Tài liệu Báo cáo khoa học: Structural and functional studies on a mesophilic stationary phase survival protein (Sur E) from Salmonella typhimurium ppt
... containing 100 lgÆmL )1 of ampicillin. A single colony was picked and cultured in 25 mL of Terrific broth overnight at 37 °C then inoculated into 500 mL of Ter- rific broth containing 2 mL of glycerol ... Biophysics Unit, Indian Institute of Science, Bangalore, India 2 Department of Biochemistry, Indian Institute of Science, Bangalore, India During stress and the stationary...
Ngày tải lên: 18/02/2014, 14:20
Tài liệu Báo cáo khoa học: Structural and functional specificities of PDGF-C and PDGF-D, the novel members of the platelet-derived growth factors family docx
... cells, indicating the possibility of PDGF- D ⁄ PDGFR-b constituting an autocrine loop, and PDGF-B acting in a paracrine manner to promote proliferation and migration of mesangial and intersti- tial ... be involved in all three phases (in ammation, proliferation and remodelling ⁄ matur- ing) of wound healing [75]. Extensive expression and secretion of full-length PDGF-C...
Ngày tải lên: 19/02/2014, 07:20
Báo cáo khoa học: Energetic and metabolic transient response of Saccharomyces cerevisiae to benzoic acid docx
... decrease in O 2 concentration in both the gas and liquid phases and the rapid increase in CO 2 concentration in both phases following the shift in benzoic acid concentration reflect a rapid increase in ... the presence of benzoic acid introduces an independent ATP drain in cell metabolism may also be of interest to those studying the regulation of cell energetics and...
Ngày tải lên: 07/03/2014, 04:20
Báo cáo khoa học: NMR and molecular dynamics studies of an autoimmune myelin basic protein peptide and its antagonist Structural implications for the MHC II (I-Au)–peptide complex from docking calculations ppt
... (1984) Proteins of myelin. In Myelin, 2nd edn (Morell, P., ed.), pp. 197–224. Plenum Press, New York. 31. Smith, R. (1992) The basic protein of CNS myelin: its structure and ligand binding. J. Ne ... MBP(74–85) epitope in the N-terminus could increase the b inding and affinity for I-A u because o f occupation of the P1 pocket. Recent thermodynamic a nd kinetic studies of the b...
Ngày tải lên: 07/03/2014, 16:20
Báo cáo khoa học: Covalent and three-dimensional structure of the cyclodextrinase from Flavobacterium sp. no. 92 pdf
... domain B (indicated in Fig. 2). This inserted domain participates in substrate binding and is rather variable. It is considered to play a role in determining the enzyme specificity [41]. The end of ... region in a superposition of CDase (blue with light green domain B) with the TVA-II dimer (grey with dark green domain B and pink N-terminal domain). The N-terminal domain of...
Ngày tải lên: 08/03/2014, 02:20
Báo cáo khoa học: Stability and fibril formation properties of human and fish transthyretin, and of the Escherichia coli transthyretin-related protein potx
... to the retinol- binding protein when it is loaded with retinol [1]. TTR is mainly expressed in the adult liver, the choroid plexus of the brain, and the retina [2,3]. TTR is involved in three ... pro- lines and alanines [46,47], and increased hydrogen bonding of the polypeptide chain [48–50]. In addition, improved intersubunit contacts within oligomeric pro- teins contribute t...
Ngày tải lên: 16/03/2014, 01:20
Báo cáo khoa học: Substrate and inhibitor specificity of Mycobacterium avium dihydrofolate reductase pptx
... of aspartate 27 of dihydrofolate reductase from Escherichia coli in interconversion of active and inactive enzyme conformers and binding of NADPH. J Biol Chem 265, 5579–5584. 19 Birdsall B, Andrews ... importance of D31 and L32 as substrate-binding, cofactor-binding and inhibitor- binding sites. The objectives of this study were to: (a) utilize site- directed mutagenes...
Ngày tải lên: 16/03/2014, 10:20