Báo cáo khoa học: " Influence of the RNase H domain of retroviral reverse transcriptases on the metal specificity and substrate selection of their polymerase domains" potx

... monomeric enzyme when fused with the RNase H domain of MuLV RT [38]. This observation confirms the functional dependence of the polymerase domain of HIV-1 RT on the RNase H domain. Neither the ... Access Research Influence of the RNase H domain of retroviral reverse transcriptases on the metal specificity and substrate selecti...

Ngày tải lên: 12/08/2014, 04:20

... Expression of Pf MDH therefore correlates with the metabolic profile of the parasite. U nder normal physiological conditions the expression of Pf MDH is markedly lower than that of Pf LDH. Expression ... even with very h igh concentration of the enzyme protein a nd the substrates. As protons are the product of this reaction, the free energy difference is highly posi...

Ngày tải lên: 16/03/2014, 18:20

... cited. Authors’ contributions JPP realized the Monte Carlo simulation, analyzed the data and wrote the manuscript. He is the corresponding author. BMK reviewed the Monte Carlo simulation and the data ... [28]. This difference could b e due to the high dose gradient in the lung, the choice of a small breasted women and the position of the detector in the ipsil...

Ngày tải lên: 09/08/2014, 09:20

... exons 3, 4, 5 and 6) have the same length. Exons 2 and 7 have different length between the two genes because they code for the regions in which the two proteins are different. Exon 1 shows the ... complete reconstruction of the Psy1 and Psy2 genes with the annotation of introns and exons. The GenBank acces- sion numbers of the two genes are EF534740 (Psy1) and...

Ngày tải lên: 07/03/2014, 05:20

... the genetic constitution of the kx-female, male offspring of these females get their X-chromosome from the sire (see fig. 1). Thus, the proportion of male-to-female offspring ... female offspring. Sex chromosomes of !,X-females consist of two X-chromosomes and one Y- chromosome. The two X-chromosomes are attached to each other and seg...

Ngày tải lên: 09/08/2014, 22:22

... association of EP24.15 to the plasma membrane of glioma C6 cells, while the D159A point mutation had no such effect. The molecular modeling of the interaction of calcium and D93 on the surface of the ... detailed architecture of the enzyme and its interactions with substrates are deci- phered. The mutations D93A and D159A neither prevented the effect of...

Ngày tải lên: 30/03/2014, 16:20

... less than two standard deviations of the mean control group body weight were considered as growth-retarded. Body length was measured from the tip of the snout to the base of the tail. The longitudinal ... in humans [5]. The abnormalities induced depend on the organs undergoing differentiation at the time of the irradia- tion, the stage of differentiation and...

Ngày tải lên: 07/08/2014, 14:23

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Ngày tải lên: 07/08/2014, 18:21

... mm of root tip and the sheaths make the roots 15% big- ger in diameter than the NI-seedlings. If we assume that all water absorption is in the region of the hyphal sheaths in I-seedlings and ... 1). The lower hydraulic resistance of the leaf blade recorded in I- versus the NI-seedlings would further favor the water transport within the leaf. Perhaps the most co...

Ngày tải lên: 08/08/2014, 14:22

... explored for the purpose of this study. These 6 patients were older than the others and some of them had slight vessel calcifications, which facilitated delination. As already described [5], the planning ... vulnerable to the effects of ionising radiation [11]. Radiation of the endothelium might cause early func- tional alterations such as pro-inflammatory responses and...

Ngày tải lên: 09/08/2014, 10:21