Báo cáo y học: "Analysis of adenovirus trans-complementation

Báo cáo y học: "Analysis of adenovirus trans-complementationmediated gene expression controlled by melanoma-specific TETP promoter in vitro" ppsx

... deliv- ery of therapeutic genes is one of the main goals of cancer therapy, it may be of importance for the general usage of the binary Ad expression system to investigate whether this finding is ... within a few days, but frequently became undetectable by one month after injection. These findings were ascribed to either elimina- tion of viral genomes by the immune system...

Ngày tải lên : 12/08/2014, 04:20

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Báo cáo y học: " Analysis of HIV-1 Vpr determinants responsible for cell growth arrest in Saccharomyces cerevisiae" ppt

... protein-induced cytostatic effect in budding yeast. Interestingly, several Vpr mutants, mainly in the N- and C- terminal domains, which were previously reported to be defective for cell-cycle ... purposes) inducing growth arrest in budding yeast and strongly sug- gest that the mechanism(s) underlying Vpr-induced cytostatic effect in budding yeast are distinct from those implicated in...

Ngày tải lên : 13/08/2014, 13:20

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Báo cáo y học: " Preparation of RGD-modified Long Circulating Liposome Loading Matrine, and its in vitro Anti-cancer Effects"

... reconstitutes in solvent. Because matrine is a strongly hydrophilic and w eakly alkaline drug, the encapsulation efficiency of liposomes for loading matrine is very low when prepared by routine ... freeze-drying, was separated by mini-gel columns of Sephadex-G50 prepared in advance. In brief, incubation mixtures of 200μL containing unloaded matrine and RGD-M-LCL wer...

Ngày tải lên : 26/10/2012, 08:57

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Báo cáo khoa học: Analysis of dopamine transporter gene expression pattern ) generation of DAT-iCre transgenic mice doc

... the intermediate lobe. Dopaminergic neurons are able to synthesize dopamine because they contain the rate-limiting enzyme tyrosine hydroxylase (TH) and the widely expressed 3,4-dihydroxyphenylalanine ... expression in hypothalamic nuclei in detail. The expression proﬁle of tyrosine hydroxylase (an enzyme required for dopamine synthesis) was broader than that of b-galactosidase...

Ngày tải lên : 30/03/2014, 08:20

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Báo cáo y học: "Characterization of histopathology and gene-expression profiles of synovitis in early rheumatoid arthritis using targeted biopsy specime" pot

... modifications involving the degree of proliferation of synovial cells, typical palisading of synovial cells in the intimal lining layers, non-foreign-body-type giant cells in the lining regions, lymphoid ... differences in the clinical course of cases in groups I and II. Conclusion In this study, we analyzed gene- expression profiles in the synovial lining tissues in...

Ngày tải lên : 09/08/2014, 06:23

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Báo cáo y học: "Assessment of immune response to repeat stimulation with BCG vaccine using in vitro PBMC model" pdf

... Galic SM: Enhancing the protective efficacy of Mycobacterium bovis BCG vaccination against tuberculosis by boosting with the Mycobacterium tuberculosis major secretory protein. Infect Immu 2005, ... analyzed using FlowJo software by gating on the lymphocyte population in forward scatter (FSC) and side scatter (SSC). The gate was set around the lymphocytes to exclude other cells fr...

Ngày tải lên : 11/08/2014, 08:21

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Báo cáo y học: " Inhibition of HIV-1 gene expression by Ciclopirox and Deferiprone, drugs that prevent hypusination of eukaryotic initiation factor 5A" potx

... catalyzed by DHS, of an aminobutyl moiety (blue) from spermidine onto the side chain of eIF5A lysine-50, yielding deoxyhypusine (Dhp); and its subsequent hydroxylation, catalyzed by DOHH, yielding ... implicated in HIV-1 replication. This protein contains the apparently unique amino acid hypusine that is formed by the post-translational modification of a lysine residue catalyze...

Ngày tải lên : 12/08/2014, 23:22

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Báo cáo y học: "Dissection of a metastatic gene expression signature into distinct components" ppsx

... During the sec- ond amplification round, aminoallyl-UTP was incorporated into the generated cRNA, enabling direct coupling of fluophores before hybridization. Direct coupling of cy5 or cy3 fluophores ... contributions of large numbers of genes for accurate prediction. This also indicates that the metastatic phenotype is caused by relatively minor changes in expression of a l...

Ngày tải lên : 14/08/2014, 17:22

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Báo cáo y học: "Onset of efficacy with acute long-acting injectable paliperidone palmitate treatment in markedly to severely ill patients with schizophrenia: post hoc analysis of a randomized, double-blind clinical trial" doc

... once-monthly paliperidone palmitate (PP), a long-acting atypical antipsychotic initiated by day 1 and day 8 injections, in a markedly to severely ill schizophrenia population. Methods: Subjects entering ... respectively) Alphs et al. Annals of General Psychiatry 2011, 10:12 http://www.annals-general-psychiatry.com/content/10/1/12 Page 3 of 10 PRIMARY RESEARCH Open Access Onset of ef...

Ngày tải lên : 09/08/2014, 01:21

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Báo cáo y học: "Analysis of HLA DR, HLA DQ, C4A, FcγRIIa, FcγRIIIa, MBL, and IL-1Ra allelic variants in Caucasian systemic lupus erythematosus patients suggests an effect of the combined FcγRIIa R/R and IL-1Ra 2/2 genotypes on disease susceptibility" pptx

... disease. This finding illus- trates that combinations of polymorphic genes may act in concert in the pathogenesis of SLE, a concept that may be instrumental in the analysis of the genetics of SLE as ... University. Genetic analyses DNA was extracted by the salting-out method described by Miller and colleagues [18]. Analysis of genetic polymor- phism was predominantly perfo...

Ngày tải lên : 09/08/2014, 01:24

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