ORGANIC POLLUTANTS: AN ECOTOXICOLOGICAL PERSPECTIVE - CHAPTER 11 pptx

... strains, another from the Andover area may owe its resistance to enhanced detoxication by a P450-based monooxygenase. 11. 7 Summary Warfarin and the second-generation superwarfarins are anticoagulant ... that can degrade them. Such long-term storage brings the risk of long-term toxic effects in individuals and in food chains. 11. 4 Environmental fate of anticoagulant rodenticides Warfarin a...

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... transferred via rodents to terrestrial predators and scavengers that feed © 2009 by Taylor & Francis Group, LLC 228 Organic Pollutants: An Ecotoxicological Perspective, Second Edition 11. 6. ... Group, LLC 224 Organic Pollutants: An Ecotoxicological Perspective, Second Edition 11. 5 TOXICITY The mode of action of warfarin and related rodenticides is illustrated in Fig...

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... an ecotoxicological perspective / Colin H. Walker. 2nd ed. p. cm. Includes bibliographical references and index. ISBN 97 8-1 -4 20 0-6 25 8-8 (alk. paper) 1. Organic compounds Toxicology. 2. Organic ... 218 1Chapter 1 Anticoagulant Rodenticides 219 11. 1 Background 219 11. 2 Chemical Properties 219 11. 3 Metabolism of Anticoagulant Rodenticides 221 11. 4 Environmental...

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... Taylor & Francis Group, LLC Factors Determining the Toxicity of Organic Pollutants to Animals and Plants 31 inhibited by, planar molecules (e.g., planar PAHs and coplanar PCBs). This can be explained ... 2.15 Glutathione-S-transferase attack on organochlorine compounds. © 2009 by Taylor & Francis Group, LLC Factors Determining the Toxicity of Organic Pollutants to Animals and Pla...

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... terrestrial and aquatic food chains, situations in which fate is determined by both biological and chemical processes. © 2009 by Taylor & Francis Group, LLC 70 Organic Pollutants: An Ecotoxicological ... examples illustrate the dangers of hasty or supercial judgment in envi- ronmental risk assessment, and the importance of rigorous case-by-case analysis. Another factor that can...

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... 14.3 in Chapter 14), as, for instance, in the case of changes in the transmission of action potential © 2009 by Taylor & Francis Group, LLC 94 Organic Pollutants: An Ecotoxicological Perspective, ... (b) Dis- appearance of persistent organochlorine insecticides from soils (from Walker et al. 2000). © 2009 by Taylor & Francis Group, LLC 92 Organic Pollutants: An Eco...

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... mouse, and not in birds (Korte and Arent 1965, Walker 1980, Chipman and Walker 1979). In general, © 2009 by Taylor & Francis Group, LLC 102 Organic Pollutants: An Ecotoxicological Perspective, ... pollutants with a single mechanistic biomarker assay. The situation © 2009 by Taylor & Francis Group, LLC 110 Organic Pollutants: An Ecotoxicological Perspective, Secon...

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... & Francis Group, LLC 138 Organic Pollutants: An Ecotoxicological Perspective, Second Edition P450s of gene family 2 (CYP 2) are more catholic, and can metabolize both planar and nonplanar PCBs. Having ... log K ow 4,4b-DCB Coplanar 7.32 6.53 5.33 2b,3,4-TCB Coplanar 6.88 6.52 5.78 2,2b,5,5b-TCB Nonplanar 7.60 7.06 6.18 2,2b,4,5,5b-PCB Nonplanar 8.02 7.40 6.36 2,2b,3,3b,4,4b-HCB...

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... 160 Organic Pollutants: An Ecotoxicological Perspective, Second Edition was evidence of reduced reproductive success in 1994, and of high rates of aban- donment of nests and supernormal ... Taylor & Francis Group, LLC 152 Organic Pollutants: An Ecotoxicological Perspective, Second Edition process. Relatively high levels of 2,3,7,8-TCDD occurred in a herbicide formula- ti...

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... lipophilic forms of organomercury and organotin, can readily cross membranous barriers such as the © 2009 by Taylor & Francis Group, LLC 164 Organic Pollutants: An Ecotoxicological Perspective, Second ... R–Hg–X, where R is an organic group and X is usually an inorganic group (occasionally a polar organic group such as acetate). The organic group is nonpolar (or rel...

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