Báo cáo y học: "Hepatitis B virus core protein with hot-spot mutations inhibit MxA gene transcription but has no effect on inhibition of virus replication by interferon a" pptx

... Hepatitis B virus core protein with hot- spot mutations inhibit MxA gene transcription but has no effect on inhibition of virus replication by interferon a. Virology Journal 2010 7:278. Submit your ... inhib ition of MxA gene tran- scription by WT HBc or its hot-spot mutants has no impact on inhibition of HBV replicatio n by IFN-...

Ngày tải lên: 12/08/2014, 01:22

... A. Genotypes E and F were not iso- lated from any of our patients, indicating that these geno- Table 2: Distribution of HBV genotypes by patient age Age group (years) Genotype A (N) Genotype C ... nine subtypes on the basis of HBsAg determinants[27], a genetic classification based on the comparison of com- plete genomes has defined eight genotypes of HBV (A to H). Difference...

Ngày tải lên: 12/08/2014, 04:20

... Gastroenterology 1994;106:1048- 1053. 43. Shih CM, Lo SJ, Miyamura T, Chen SY, Lee YH. Suppression of hepatitis B virus expression and replication by hepatitis C virus core protein in HuH-7 ... chronic HCV infection [18]. The result indicated that onset of hepatitis B may reduce the severity of HCV infection but not frequency of chronicity. Similar to this study...

Ngày tải lên: 02/11/2012, 09:51

... from clones with wild-type core promoter sequence), which abolished recognition of both core protein and HBeAg by a rabbit polyclonal antibody (Kim et al., unpublished). This finding is consistent ... disulfide bond HBeAg has a secondary structure quite different from that of core protein [22, 35]. Only one of the two major B cell epitopes of HBeAg is shared with...

Ngày tải lên: 03/11/2012, 09:46

... http://www.virologyj.com/content/6/1/128 Page 4 of 9 (page number not for citation purposes) Phylogenetic analysis of pre-S region of HBVFigure 1 Phylogenetic analysis of pre-S region of HBV. Phylogenetic ... depend only on virus mutations, but also host factors, and therefore needs further investiga- tion. Conclusion HBV /B and HBV/C are dominant in Makassar, similar with...

Ngày tải lên: 12/08/2014, 04:20

... was remarkable for hepatosplenomegaly. Subsequently, the patient underwent a bone marrow biopsy that showed a hypercellular marrow with erythroid hyperplasia, but no evidence of dysplasia or lymphoma. ... reported case of a pa tient with mixed- type AIHA who did not respond to steroid therapy but showed a complete response to only one cycle of rituxi- mab. Refractory AIHA is a...

Ngày tải lên: 11/08/2014, 00:23

... latter in the bone tissue. Enhanced activity of oste oclasts and osteoblasts leads to bone resorption and a reduction of bone mineral concentration with an increased proliferation of fibrous tissue ... did not confirm the other lesions described on tomography. A tomography-guided biopsy specimen (Figure 1) was obtained, but histopathological analysis reported normal tissue compone...

Ngày tải lên: 11/08/2014, 17:21

... allergic bronchopulmonary aspergillosis, and possibly even asthma may also be associated with mutations in the CFTR gene, but those syndromes predominantly reflect non-CFTR gene modifiers and environmental ... muta- tions may influence the efficiency of normal/abnormal CFTR mRNA transcription to varying degrees. In turn, the severity of the abnormality in CFTR may relate direct...

Ngày tải lên: 12/08/2014, 18:20

... concept of co-morbid- ity, according to DSM-IV classification diagnostic system, and abandon the ICD-10 philosophy of emphasizing one main diagnosis in each patient. Conclusion This study provides ... psy- chopathology: factor structure, reliability, validity, and diag- nostic sensitivity. J Abnorm Child Psychol 1997, 25:487-497. 18. Barkley RA, Murphy KR: Attention-Deficit Hyperactivity...

Ngày tải lên: 13/08/2014, 18:21

... baculovirus- expressed HCV proteins and Western blot analysis in order to be sure of the specificity of the antibody responses to a given protein. One of the drawbacks of the assay is, however, that only antibodies ... 0 The prevalence of anti-HCV antibodies were analysed by Western blot analysis with recombinant HCV proteins in 68 patients with chronic HCV infection caused...

Ngày tải lên: 12/08/2014, 04:21