Particle Toxicology - Chapter 10 ppt

... J., and Mossman, B. T., Silica-induced activation of c-Jun-NH2-terminal amino kinases, protracted expression of the activator protein-1 proto-oncogene, fra-1, and S-phase alterations are mediated ... 200 10. 4.1 Mitogen-Activated Protein Kinases, Fos/Jun Family Members, and Activator Protein-1 200 10. 4.2 Nuclear Factor-k B 202 10. 4.3 Other Signaling PathwaysInduced by Particulates 204 1...

Ngày tải lên: 11/08/2014, 21:21

... (Ca,Na 2 ,K 2 )Al 2 Si 10 O 24 7(H 2 O); natrolite, Na 2 Al 2 Si 3 O 10 2H 2 O; paranatrolite, Na 2 Al 2 Si 3 O 10 3H 2 O; tetranatrolite, Na 2 Al 2 Si 3 O 10 2H 2 O; scole- cite, CaAl 2 Si 3 O 10 3H 2 O: ... “nanostructured particles,” as long as their activityisgoverned by their nano- particle components.For example, an agglomerateofTiO 2 nanoparticlesformingasingle “nanostructu...

Ngày tải lên: 11/08/2014, 21:21

... Activation of NF-kappaB by PM (10) occurs via an iron-mediated mechanism in the absence of IkappaB degradation, Toxicol. Appl. Pharmacol.,166, 101 – 110, 2000. Karin, M., The NF-kappa Bactivation ... sequences calledTPA-response element (TRE) or AP-1sites (Donaldson et al. 2004). AP-1 transcription factorsinclude homo- (Jun/Jun) andheterodimer(Fos/Jun) complexesencodedbyvarious members of th...

Ngày tải lên: 11/08/2014, 21:21

... of inhaled ultrafine particles to the brain, Inhal. Toxicol.,16, 437–445, 2004. Osornio-Vargas, A. R., Bonner, J. C., Alfaro-Moreno, E., Martinez, L., Garcia-Cuellar, C., Ponce-de-Leon- Rosales, S., ... IL -1 0 and IL-6 and less IL-8 and IL-1b than age/gender/socioeconomic matchedcontrols, indicating ashift in the circulating cytokine profile in favor of anti-inflammatorycytokines(Caldero ´ n-G...

Ngày tải lên: 11/08/2014, 21:21

... consulted before any final spec- ifications or bids are prepared. L1306/frame/pt02 Page 101 Friday, June 23, 2000 1:55 PM © 2001 by CRC Press LLC SERIAL DATA OUTPUT 103 Particle counters requiring ... Data output from the particle counter will consist of several “strings” of infor- mation. There are usually four or more particle size ranges, each a separate data point. Most part...

Ngày tải lên: 18/06/2014, 19:20

... drop of blood. In time, after many squeezes, Tom managed to sign his initials, using -1 1 3- -1 1 1- Muff Potter, of course. But if a man was dead sober, I reckon maybe that whack might ... brass andiron knob! This final feather broke the camel's back. -1 1 9- THE ADVENTURES OF TOM SAWYER CHAPTER 10 THE two boys flew on and on, toward the...

Ngày tải lên: 24/12/2013, 14:16

... information from R3: Connected to neighbor R1 on network 10. 3.0.0/16, cost of 5 Connected to neighbor R4 on network 10. 7.0.0/16, cost of 10 Has a network 10. 6.0.0/16, cost of 2 R1 Processes the LSPs from ... Link-State Packet  Step 3: Each router builds a link-state packet (LSP) containing the state of each directly connected link. Implementing Link-State Routing  Advantages...

Ngày tải lên: 23/02/2014, 09:20

... securely securely  does require real-time access to directory when keys does require real-time access to directory when keys are needed are needed Chapter 10 – Chapter 10 – Key Management; Key ... directory  public-key authority public-key authority  public-key certificates public-key certificates Hybrid Key Distribution Hybrid Key Distribution  retain use of private-key K...

Ngày tải lên: 15/03/2014, 17:20

... CHNS, carbon-hydrogen-nitrogen-sulfur; ED, electron diffraction; EDX, energy dispersive x-ray; GC-MS, gas chromatography mass spectrometry; HRGS, high-resolution γ spectroscopy; ICP-MS, inductively ... Environment 10. 3.2.3 Sample Storage and Transportation 349 10. 3.3 The Nuclear Forensics Laboratory 350 10. 3.3.1 Introduction 350 10. 3.3.2 Imaging Techniques 352 10. 3.3.3 Bulk Analysi...

Ngày tải lên: 18/06/2014, 19:20

... effects of subtoxic dose of a NaF (10 mg F/kg body weight) on the activities of glucose-6-phosphate dehydrogenase (G6PD) in the submandibular glands of fed and overnight-fasted rats and observed that ... leaves with tip necrosis. LA4154/frame/C10 Page 129 Friday, May 19, 2000 9:27 AM © 2001 by CRC Press LLC 123 CHAPTER 10 Environmental Fluoride 10. 1 INTRODUCTION Fluorine is...

Ngày tải lên: 18/06/2014, 22:20