báo cáo khoa học: " Autologous bone marrow stem cell intralesional transplantation repairing bisphosphonate related osteonecrosis of the jaw" docx

... 7:16 http://www.head-face-med.com/content/7/1/16 Page 3 of 6 CASE REP O R T Open Access Autologous bone marrow stem cell intralesional transplantation repairing bisphosphonate related osteonecrosis of the jaw Luigi Cella 1 , Aldo Oppici 1 , ... offered the opportunity to our patient of injection of autologous bone marrow stem cells into the osteonec...

Ngày tải lên: 11/08/2014, 20:21

... not observed in the BMC since the number of eGFP-positive cells closely matched the proportion of cells carrying provirus. However, the level of provirus was below the limit of quantification ... increase the number of eGFP-positive cells in the bone marrow compart ment, corroborating the idea that silencing was not an issue in these cells. Evaluation of provir...

Ngày tải lên: 12/08/2014, 04:21

... this effect depends on tethering the C-terminal ends of the extracytoplasmic domains. Discussion The rationale for the present study was to improve understanding of how the subunits of the multimeric M6P ... of this type exhibit the predicted amount of binding only if the heterodimer is tethered by the wild-type partner. By contrast, we found that, if the heterod...

Ngày tải lên: 18/02/2014, 08:20

... between the worlds of ideas and of experimental data. The world of ideas includes theories, hypotheses, human knowledge and any other mental constructs, while the world of data consists of experimental observations ... occur in the earlier phases we may need to return and cor- rect them in the light of further knowledge). (C) The hallmark of modelling as a comparison...

Ngày tải lên: 07/03/2014, 12:20

... center of the enzyme. These modifications may be attributed to either the presence of the substrate and/or a product in the vicinity of the T2Cu active center rather than to disruption of this ... 271) 2365 from the electrode and donates them to the Nir, in the presence of nitrite. Under these conditions, the shape of the voltammogram becomes sigmoidal, with an...

Ngày tải lên: 07/03/2014, 15:20

... to gene expression. The status of the switch is determined by the state of the upstream regulatory element of the GAL genes in the nucleus. The regulatory protein may bind to the upstream regulatory ... constrain the operation of the network. However, the response for a specific system is constrained by the connection between these elements. The r esponse is a...

Ngày tải lên: 07/03/2014, 16:20

... been implicated in all but one of the predicted reactions in the GPI pathway. The exception is the addition of the second mannose to the GPI core. We show here that depletion of the essential, multispanning ... Ybr004cp func- tions upstream of Smp3p. Together, these data further support the conclusion that Ybr004cp functions in the yeast GPI assembly pathway. Sequenc...

Ngày tải lên: 07/03/2014, 16:20

... region of Prm3. Deletion of the PPARc (a) and RXR III half sites to generate the )170 subfragment retained 15d-PGJ 2 -suppression of Prm3 activity. On the other hand, either deletion of the PPARc ... anti atherosclerotic role for PPARc has been suggested due to the inhibitory effects of PPARc activation on the expression of a number of pro-atherosclerotic, pro-thromb...

Ngày tải lên: 07/03/2014, 21:20

... Fur- thermore, the GBP-dependent expression of both enzyme genes was observed in the presence of the MEK inhibitor, thereby demonstrating that the GBP- dependent enhancement of expression of the ... after addition of GBP to the incubation medium of MaBr4 cells. The involvement of a MAP kinase kinase (MEK) in the ERK activation pathway [19] was tested by evaluatin...

Ngày tải lên: 30/03/2014, 04:20

... RNA synthesis was measured as RNA labeling in the presence of 2 lCiÆmL )1 of [ 3 H]uridine [6]. Cell viability Cell viability was estimated by counting colored cells after incubation of cell suspensions ... RNA and protein synthesis [6], suggesting the de novo expression of genes involved in suppression of the cell death machinery. This hypothesis was confirmed by prote...

Ngày tải lên: 30/03/2014, 08:20