báo cáo khoa học: " Characteristics of inmates witnessing overdose events in prison: implications for prevention in the correctional setting" doc

... warrant assessing the feasibility and the effectiveness of peer interventions among drug users in prison. In spite of the difficulties in accepting drug use in prison, administrators of correctional ... explores the fre-quency with which inmates report having witnessed drug overdose events while in the prison setting. We explorewhether inmates reporting to have witnessed an overdose event or overdose ... Institute of Forensic Sciences for the period of 2002through 2007 indicates that overdose deaths are indeedoccurring within this prison setting. Of 351 deceasedprison inmates transferred from the prison...

báo cáo khoa học: " Characteristics of successfully implemented telemedical applications" docx

... at the expense of produc-ing evidence of the effect of telemedicine. In these studies, the motivation for introducing telemedicine is not evi-dence of the effects of telemedicine per se. Rather, ... goals andmethods of practice, and their involvement in planningand carrying out the implementation. Organization of training in the use of the technology, implementation of in- depth evaluation ... routines for the use of telemedical applications.LaMonte et al. [26] describe the establishment of fixedroutines for training in the use of the technology in response to frequent changes in...

báo cáo khoa học:" Characteristics of maxillofacial injuries resulting from road traffic accidents – a 5 year review of the case records from Department of Maxillofacial Surgery in Katowice, Poland" pot

... noted in spring. The incidence of these injuriesvaries depending on the time of the day and is the highestbetween noon and 4 PM during the day rush hour. The relatively high incidence of injuries ... gender, we obtainedinformation on the pattern of injury and detailed descrip-tion of accident (the date and the time of accident). The data concerning the role of the patient in accident was ... improving the safety in motor vehicles,traffic accidents are still among the main reasons of maxillofacial injuries. The maxillofacial injuriesremain the serious clinical problem because of the...

Báo cáo khoa học: "Characteristics of equine summer eczema with emphasis on differences between Finnhorses and Icelandic horses in a 11-year study" pdf

... born in Finland. Of the Icelandic horses, 56 were born in Iceland, 11 in Finland,while the origin of 4 horses remained unknown. In the group of ponies, Shetland and New Forest ponies were the commonest ... and the diseaseInformation on the horses, including breed, age, sex,country of birth and time of import to Finland, wasacquired by questionnaire and interviews. In addition,features of the ... challenging. The aim of this study was to summarize the features of equine summer eczema in a long-standing study, espe-cially on the Finnhorse, the native Finnish horse breed,and the Icelandic...

Tài liệu Báo cáo khoa học: Comparison of a coq7 deletion mutant with other respiration-defective mutants in ﬁssion yeast doc

... Whereas induction of ctt1+and apt1 occurred in all ubiquinone-deﬁcient strains, induction of gpx1+was not observed in any of the tested strains (Fig. 6).However, in the wild-type strain treated ... in various ubiquinone-deﬁcient strains and in the cyc1 mutant by measuringmRNA levels of stress-inducible genes and the phosphorylation level of the Spc1 MAP kinase. Induction of ctt1, encoding catalase, ... necessary for the penultimate step in ubiquinonebiosynthesis, from the observation that the deletion mutant accumulated the ubiquinone precursor demethoxyubiquinone-10 instead of ubiquinone-10. The coq7...

Tài liệu Báo cáo khoa học: Characterization of chitinase-like proteins (Cg-Clp1 and Cg-Clp2) involved in immune defence of the mollusc Crassostrea gigas docx

... sequences of the catalytic domain of members of the GH18 familyresulted in the ampliﬁcation of an expected 147 bpsequence. Cloning and sequencing of this fragmentrevealed an ORF showing amino acid ... of the soleGlyco_18 domain, the C-terminal tail of C. gigas CLPsmay not noticeably contribute to the structure and the function of these proteins. Interestingly, Cg-Clp1 andCg-Clp2 C-terminal ... corresponding to the most 3¢-end of Cg-Clp2 was subcloned in pGEMT easy. This recombinantplasmid was used as a template for the synthesis of biotin-labelled sense and antisense cRNA probes according...

Tài liệu Báo cáo khoa học: Role of receptor-mediated endocytosis, endosomal acidiﬁcation and cathepsin D in cholera toxin cytotoxicity pdf

... amounts of proteinfrom 3Y1-Ad12 cell lysates conﬁrmed the absence of cathepsin D in nontransfected cells, and the presence of both the 31 kDa mature cathepsin D and the 45 kDa procathepsin D in cathepsin ... decrease of 3–10-fold in the apparent afﬁnity of the toxin for the enzyme [6]. More-over, both chloroquine and monensin interfered with the ATP-dependent intraendosomal degradation of internalized ... baﬁlomycin and the cathepsin D inhibitor pepstatin Apartially inhibited, both in vivo and in vitro, the cAMP response to choleratoxin. This cathepsin D-dependent action of cholera toxin under the con-trol...

Báo cáo khoa học: Suppression of a cold-sensitive mutant initiation factor 1 by alterations in the 23S rRNA maturation region pdf

... [29–32].Taking these ﬁndings together, we suggest that the R69L mutant of IF1 allows premature subunit joiningby either failing to discriminate between certain TIRelements in mRNA, or inducing a conformation ... 5¢-side of the processing stem, gave rise to rRNA with the majority of termini in the mature form, whereas pD3, with amutation on the 3¢-side, gave rise rRNA with the majority of the termini in the ... imbalances of the 30S and 50Ssubunits. The same analysis revealed that there was ageneral decrease in the amount of 50S subunits in the sucrose gradient in the case of the suppressor plasmidpD3. In...

Báo cáo khoa học: Complementation of coenzyme Q-deﬁcient yeast by coenzyme Q analogues requires the isoprenoid side chain ppt

... reduced in the presence of KCN (Fig. 3F). In the absence of FCCP or KCN, the ratio of reduced to oxidized ubiquinone was similar tothat in the presence of FCCP (data not shown). In summary, the ... just before the addition of ubiquinone-containing vesicles (I0). (F) The redox state of decylQ is largely insensitive to KCN. The BY4743Dcoq2 strain was grown in YPGG for 24 h atwhich point ... at30 °C. The growth of 21 of these fell below the range of the nine Dcoq2DORF control strains and the BY4743Dcoq2 parental strain. To ensure the defect in growth was related to an inability...

Báo cáo khoa học: Epoxidation of benzo[a]pyrene-7,8-dihydrodiol by human CYP1A1 in reconstituted membranes Effects of charge and nonbilayer phase propensity of the membrane pot

... substratesby placing the opening of the substrate access channel into the lipid bilayer. Thus the pool of substrate moleculesaccessible for P450 would c onsist of the substrate molecules in the membrane ... affect the stereoselectivity of epoxidation. The presence of the anionic lipid PtdSerincreased the formation of DE2 twice as much as that of DE1. Even the relatively small portion of the negativelycharged ... alterations in the metabolite proﬁle, i.e.they do not alter the stereoselectivity of epoxidation.Obviously, there is no alteration of the active s ite confor-mation of P450. But the s triking parallelism...

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