Báo cáo y học: "A new clinical rating scale for work absence and productivity: validation in patients with major depressive disorder" pot

... not for citation purposes) BMC Psychiatry Open Access Research article A new clinical rating scale for work absence and productivity: validation in patients with major depressive disorder Raymond ... This study seeks to validate a new clinical rating scale for work functioning and productivity in patients with MDD. Methods Scale Developmen...

Ngày tải lên: 11/08/2014, 17:20

... Morphogenic Protein (BMP) which plays a crucial role in bone formation by stimulating mesenchy- mal cells and differentiating them into osteoblasts [11]. BMP has proved to be a very good tool because ... resulting in osteoclast dysfunction [4]. The pro- pensity to fracture is seen in all three types but is a major complication in the autosomal dominant form because of the normal l...

Ngày tải lên: 11/08/2014, 19:21

... of branching points; a following link index specifying the sequential index of the seg- ment which follows on the same root and, finally, the rank of the branching point giving ... each root segment is defined by the Cartesian coordinates of some characteristic points (e.g., terminal points (initial and final) and branching points where the lat...

Ngày tải lên: 09/08/2014, 02:21

... study was to explore the efficacy of orthotic treatment for mechanically induced 1 st MTP joint pain and to investigate whether any change in pain correlated with changes in foot and ankle kinematic values, ... 9 joint pa in is used commonly w ithin the rheumatology literature and refers to pain that is mechanica l in origin or influence when there is a p attern of increased...

Ngày tải lên: 10/08/2014, 21:24

... period. Laboratory analyses Blood hematology and chemistry analyses and urinalysis were performed at the Clinical Laboratory of NEMC, Boston, MA. CRP concentrations were determined by enzyme immu- noassay kit ... impaired vitamin B6 metabolism in patients with rheu- matoid arthritis results from inflammation, and these patients may be in higher demand of vitamin B6 to cope...

Ngày tải lên: 09/08/2014, 07:20

... specifically interact with the tyrosine motifs pY401 and pY429pY431. pY429pY431 was more potently recruiting SOCS-3 than pY401, reflecting the high affinity binding determined by SPR. The nonphosphorylated ... specifically binds to the receptor motifs encompassing tyrosines pY401 and pY429pY431 in COS7 cells In order to investigate whether SOCS-3 binds to the receptor motifs containing...

Ngày tải lên: 24/03/2014, 00:21

... fusion constructs. Tyrosine phosphorylation (minus GST alone) of GST– cyto-wt with individual tyrosine kinases in a cell-free format.Tyrosine phosphorylation of GST–cyto-wt and GST–cytoY !F mutants with a mix ... Binding specificities of the sialoadhesin family of I-type lectins. Sialic acid linkage and substructure requirements for binding of myelin- associated glycoprotein, Schwa...

Ngày tải lên: 24/03/2014, 04:21

... challenge for the future. As this understanding is gained, H-tunneling can then be used as a tool for (a) increasing the catalytic efficiency of enzymes in the biotechnology industry (by enhancing the ... 269) 3101 MINIREVIEW A new conceptual framework for enzyme catalysis Hydrogen tunneling coupled to enzyme dynamics in flavoprotein and quinoprotein enzymes Michael J. Sutcliffe 1...

Ngày tải lên: 31/03/2014, 23:20

... several proteins by deimination of arginine residues by peptidy- larginine deiminases [3,4]. The citrulline moiety is the true determinant in proteins recognized by antiperinuclear factor [5], antikeratin ... divided into three biochemical subgroups, as follows: group 1 = G for glycine, A for alanine, V for valine, L for leucine (aliphatic amino acids (nonpolar hydrophobic)); group...

Ngày tải lên: 09/08/2014, 10:20

... they returned the device for data analyses. In addition to wear- ing the Daysimeter, participating nurses provided urine samples, obtained every four hours, for subsequent mela- tonin assay and ... stability (IS) statistics for the day-shift and rotating-shift nurses (a) and for the two groups of rats (b)Figure 10 Interdaily stability (IS) statistics for the day-shift and...

Ngày tải lên: 10/08/2014, 09:20