Báo cáo y học: "Proteome analysis of schizophrenia patients Wernicke''''''''s area reveals an energy metabolism dysregulation" potx

... evolution from monkeys to humans may have led to the appearance of SCZ due to changes affecting energy pathway genes [41]. The altera- tion of this pathway, specifically the glycolysis and gluco- neogenesis ... citation purposes) BMC Psychiatry Open Access Research article Proteome analysis of schizophrenia patients Wernicke's area reveals an energy metabolism dys...

Ngày tải lên: 11/08/2014, 17:20

... were found between the three groups and confirmed by Principal Component Analysis (PCA). Conclusion. Analysis of BAL proteomes of PLCH patients and of smoker and non-smoker controls also proved ... controls and Pulmonary Langerhans cell Histiocytosis (PLCH) are visualized by ¥ and significant differences occurring between no-smoking controls and Pulmonary Langerhans cell His...

Ngày tải lên: 10/08/2014, 09:22

... importance of Fas and FasL [15], and that of TNF-R1 and TNF-α[16], in preeclampsia. Thus, hypoxia-induced changes in the expression of both proapoptotic and antiapoptotic proteins, and the balance ... identify key molecules in the course of hy- poxia-induced apoptotic pathways. Such analysis of trophoblastic cells will, in the near future, yield in- sights into the mechanisms...

Ngày tải lên: 31/10/2012, 15:12

... ABI PRISM Big Dye Terminator system (Applied Biosystems, Germany). Sequences were analyzed using the Chromas software (Technely- sium Pty Ltd, Tewantin, Australia) and GeneDoc software (http://www.psc.edu/biomed/genedoc ). ... Results Mutational analysis of hCDC4 in AML In this study the common exons 2 to 11 and the three known transcript variants of exon 1 of hCDC4 (Figure 1A)...

Ngày tải lên: 31/10/2012, 16:49

... in thymocytes with age. As shown in Table 4, real time RT-PCR confirmed the increased levels of many of these genes identified in the array analysis. Moreover, Western blot analysis of thymo- cyte ... age, as flow cytometric analysis for B220, CD38 and CD138 on the thymocytes as well as RT-PCR analysis for the plasma cell markers, blimp1 and XBP1, failed to demonstrate any sign...

Ngày tải lên: 03/11/2012, 11:35

... equimolecular amount of DM43 to the enzymes. Statistical analysis Results represent mean ± SEM (n ‡ 4). Data were statis- tically evaluated by Analysis of Variance ( ANOVA ), followed by Newman-Keuls-Student’s ... deglycosylation DM64 was chemically deglycosylated with anhydrous trifluoromethanesulfonic acid (TFMS) using the GlycoFree kit k-500 from Oxford GlycoSystems, USA and submitt...

Ngày tải lên: 21/02/2014, 01:21

... H.S., Han, Y. & Fung, B.K K. (2000) Subunit e xchange of small h eat sho ck proteins. Analysis of olig- omer formation of aA-crystallin and Hsp27 by fluorescence res- onance energy transfer and ... 937 Functional analysis of a small heat shock/a-crystallin protein from Artemia franciscana Oligomerization and thermotolerance Julie A. Crack, Marc Mansour, Yu Sun and Thomas H....

Ngày tải lên: 22/02/2014, 04:20

... Primary antibody, 24 sera from untreated CD patients. (B) Primary antibody, 12 sera from non-CD patients affected by other pathologies and with a serum antibody response to tTG. Secondary antibodies, ... phage carrying a single antibody specificity. We have recently made and selected phage antibody libraries from lymphocytes of CD patients [16]. We were able to isolate single-chain antib...

Ngày tải lên: 08/03/2014, 09:20

... carrying four acyl residues. GlcN residue A had unsubstituted hydroxyl group at C-1, and was mostly present in an a-pyranose form. Acyl 1 ,acyl 2 and acyl 3 residues had hydroxy or acyloxy groups ... 2-N-(3-O- acyl 4 -acyl 2 )-b-GlcN-(1–6)-2-N-acyl 1 )3-O-acyl 3 -GlcN where acyl 1 ,acyl 2 and acyl 3 are 3-hydroxyhexadecanoic or 3-hy- droxyoctadecanoic acids, acyl 4 is tetradecanoic or (mino...

Ngày tải lên: 08/03/2014, 09:20

... Iolation and chemical analysis of 7-O-(2-amino-2-deoxy-a- D -glucopyranosyl- L -glycero- D -manno-heptose as a constituent of the lipopolysaccharides of the UDP-galactose epimerase less mutant J-5 of ... L, and M were those of the outer core and the NMR analyses confirmed the results obtained by methylation analysis [9]. Long-range NOEs were observed between H-3a (strong) and H-3...

Ngày tải lên: 08/03/2014, 09:20