báo cáo khoa học: " A work force model to support the adoption of best practice care in chronic diseases – a missing piece in clinical guideline implementation" ppt

... of Australia(NHMRC): A guide to the development, evaluation and implementation of clinical practice guidelines Canberra: Commonwealth of Australia;1999. 3. National Institute of Clinical Studies ... work- force planning, health services planning, education, andtraining policy, and whether these in turn support the adoption of clinical best practice care and are expectedimprovements in patient ... adoption of care defined by clinical best practice guidelines is widely regarded as desirable, and the extent to which clinical practice conforms to best practice is onemeasure of health sector performance.Published:...

A work force model to support the adoption of best practice care in chronic diseases – a missing piece in clinical guideline implementation pot

... purposes)Implementation ScienceOpen AccessDebate A work force model to support the adoption of best practice care in chronic diseases – a missing piece in clinical guideline implementationLeonie Segal*, ... Council(NHNRC) of Australia Guide to the Development, Evalu-ation and Implementation of Clinical Practice Guidelines[2]). The adoption of care defined by clinical best practice guidelines is widely regarded ... knowledge of clinical practice guideline by cliniciansThis requires that guidelines are written in a way that isclear to clinicians and translatable into actions and aneffective dissemination strategy.2....

Tài liệu Báo cáo khoa học: An engineered disulﬁde bridge mimics the effect of calcium to protect neutral protease against local unfolding docx

... the unfolding.Calcium ions are the main contributory factor to enzyme stability The binding of calcium ions seems to be the mainsource of stabilization of the neutral protease fromB. stearothermophilus. ... (Stratagene, Heidelberg, Germany), the primers5¢-GTTTTGCCCGGCAGCTTGTTTACCGATGGCGACAACCAA-3¢ (forward) and 5¢-TTGGTTGTCGCCATCGGTAAACAAGCTGCCGGGCAAAAC-3¢ (reverse), and the wild-type gene of the ... assuming that inactivation is determinedby autoproteolysis as a consequence of rate-limitingunfolding. A separate kinetic analysis of conformation-al unfolding, however, is hampered by autoproteolysis.Recently,...

Tài liệu Báo cáo khoa học: "From HOPE en I''''ESPERANCE On the Role of Computational Neurolinguistics in Cross-Language Studies " pptx

... depending on the input, interconnections to other information, and an automatic activity decay scheme. In addition, the decay scheme is based on the state of the information, whether it has reached ... when information reaches threshold and fires. It can be INHIBITORY and EXCITATORY in its effect. INTERPRETATION is a result of acti- vation of a pragmatic representation of a disambiguated ... fically in agrammatics and Broca's aphasics. French neurolinguistic studies have documented a similar degradation in the ability of agrammatic and Broca's aphasics (LeCours and Lhermitte,...

Tài liệu Báo cáo khoa học: "Language Resources Factory: case study on the acquisition of Translation Memories" potx

... installation and maintenance of the tool, thus allowing all the other users to beneﬁt16 Evaluation The evaluation of the factory is based on itsfeatures and usability requirements. A binaryscheme ... the webpages in the domains and gather pairs of web documents in the target languages that belong to the targetdomain. Second, we apply a sentence aligner.14It takes as input the pairs of documents ... introduce a completely new paradigm in the way we use software tools. Before, everyresearcher or laboratory had to install and main-tain all the different tools that they needed fortheir work, ...

Báo cáo khoa học: cAMP increases mitochondrial cholesterol transport through the induction of arachidonic acid release inside this organelle in Leydig cells pdf

... directuptake of AA itself inside the mitochondria or by the previous esteriﬁcation to AA-CoA by ACS4 and subse-quent action of Acot2 to render free AA in the mito-chondria. The fact that cAMP increases ... due to the fattyacid itself but to the acyl-CoA available to the mito-chondrial Acot2. In our case, AA-CoA is formed pref-erentially because of the speciﬁcity of ACS4 on AA [9]. The mitochondrial ... (B) Auto-radiography spots quantiﬁcation by densitometry. The autoradio-graphies were quantiﬁed by densitometry and the data werenormalized against the intensity of the signal of unlabeled AAstained...

Báo cáo khoa học: Differing molecular mechanisms appear to underlie early toxicity of preﬁbrillar HypF-N aggregates to different cell types potx

... c, in complexwith the cytosolic factor Apaf-1 activates the caspase-dependent apoptotic pathway, whereas AIF translo-cates to the nucleus inducing chromatin condensationand large-scale fragmentation ... that activa-tion of the effector caspase 3 occurs downstream of caspase 8 and caspase 9 cleavages in response to differ-ing apoptotic stimuli; once activated, caspase 3 canactivate caspase ... destabilizing effects of the aggregates can also be hypothesized. These considera-tions may explain the lack of activation of the apop-totic extrinsic pathway and cell recovery after the initial insult;...

Báo cáo khoa học: "Estimating Upper and Lower Bounds on the Performance of Word-Sense Disambiguation Programs" docx

... performance have been made in other areas of computational linguistics, specifically part of speech tagging. For that application, it is generally accepted that the baseline part -of- speech tagging ... operational, at least as we have defined it. Ideally, the baseline system ought to try to estimate the most likely sense for each word in the vocabulary and then assign that sense to each instance ... somewhat difficult to obtain in large quantity, and what little is available is often fairly unbalanced and unrepresentative of general language. Moreover, the assumption that differences in translation...

Báo cáo khoa học: Complement factor 5a receptor chimeras reveal the importance of lipid-facing residues in transport competence doc

... the binding assays included 5 lg of totalprotein for each data point. After the membranes werethawed on ice, the protein concentration was determinedusing BSA as standard. The binding reaction ... point for assembling the TM bundle for C5aR was the X-ray structure of dark-adapted rhodopsin (Protein Databank entry: 1F88, chain A) . At the stage of helical packing, the dihedral angles Fand W ... consisted of minimization of the sum of all intra- and interhelical interatomic energies in the multidimensional space of parameters that included the ‘global’ parameters (i.e. those related to movements...

Báo cáo khoa học: An internal ribosome entry site mediates the initiation of soluble guanylyl cyclase b2 mRNA translation potx

... PCR#1(F-5¢-AACTTTCGAAGTCATGGTGG-3¢ and R-5¢-GACTTTCCAAAATGTCGTAATAACC-3¢) ampliﬁed the inter-cistronic region. PCR#2 (F-5¢-TTCCATCTTCCAGCGGATAG-3¢ and R-5¢-CTACGTGCAAGTGATGATTTAC-3¢)ampliﬁed a 525 ... by the appearance of more efﬁcientIRES structures and ⁄ or the absence of inhibitoryuORFs. The alternative leader also possess an in- frame AUG at +53 that may allow a more efﬁcienttranslation ... NouAUG 58 UGUaugG + 11 NouAUG 116 AACaugG ++ 20 YesuAUG 151 AAGaugC ) 2NouAUG 159 UUCaugA ) 39 NouAUG 171 ACAaugU + 35 NouAUG 175 UGUaugA ) 24 NouAUG 178 AUGaugA ) 23 NouAUG 234 UCCaugG...

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