báo cáo khoa học: " Simulating gene-environment interactions in complex human diseases" pdf

... simulate linked markers using genetically related individuals. Existing approaches include: resampling from existing data (for example, HapSample [8] or hapgen [9]); reconstructing from statistical ... greatly aid the study of GxE in complex human diseases. Abbreviations DPL, disease-predisposing locus; GENS, Gene-Environment iNteraction Simulator; GxE, gene-environment intera...

Ngày tải lên: 11/08/2014, 12:20

... representing default information, which we refer to as the 'main' equation set. These may be overridden by eontlleting information in a more specific class. Each equation in a main set ... from one end, changing the remainder, and then replacing the first string. In this section we show briefly how unification, string concatenation, and defensible inheritance combine t...

Ngày tải lên: 20/02/2014, 21:20

... augmenting an intel- ligent tutoring system with human- supplied ca- pabilities: Adding Human- Provided Emotional Scaffolding to an Automated Reading Tutor that Listens. In Proc. Intelligent Tutoring ... 2002. Intelligent tutoring systems with conversational dialogue. AI Magazine. P. W. Jordan, M. Makatchev, and K. VanLehn. 2004. Combining competing language under- standing approaches in...

Ngày tải lên: 08/03/2014, 04:22

... ex- ample, making tea is composed of boiling the wa- ter, preparing the tea pot, putting tea leaves in the pot, and pouring the boiled water into it, and so on. To analyze actions in dialogue as ... re- sponder succeeded in interpretation. E.g., turning to the right as the speaker intended in response to the request “turn to the right.” 3.3 Partial and mid-DU Grounding In Traum’s gr...

Ngày tải lên: 08/03/2014, 21:20

... subtler problem in pro- nominal reference, namely, the proper treatment of pronouns occurring within belief-contexts. i. OUASI-INDICATORS Following Casta~eda (1967: 85). an indic,tot is a ... sentences involv- ing iterated belief contexts. Consider (10) John believes that Mary believes that Lucy is rich. The interpretation of this that we are most interested in representing trea...

Ngày tải lên: 17/03/2014, 19:21

... in the binding of C-terminal binding protein- interacting domains despite great variability in their amino acid sequences. Finally, this L225A point mutation could also provide useful knock -in ... HIC1–CtBP interaction in tumorigenesis and in development. Abbreviations AD, activation domain; CID, CtBP-interacting domain; CR, central region; CtBP, C-terminal binding protein; DBD, DNA...

Ngày tải lên: 23/03/2014, 10:21

... lacking in their ability to accurately model the complex process that is human turn- taking. This research analyzes a human- human tutoring corpus in order to identify prosodic turn-taking ... turn-taking in tutoring, so we hope to inves- tigate it further while using a human- human (HH) tutoring corpus and language technologies to ex- tract useful information about turn-tak...

Ngày tải lên: 30/03/2014, 21:20

... that, 'Critical Care Medicine is increasingly used and prominent in a shrinking U.S. hospital system'. In addition, during recent decades there was increasing utilization of intensive care unit (ICU) ... years incurred five to six times that rate [5]. Intensive care medicine is a unique discipline. It is practised by physicians from several primary specialties, all having specia...

Ngày tải lên: 12/08/2014, 22:21

... FEBS sion of SREBP-1 in the brain does increase in mice during aging [39], a phenomenon also observed in the peripheral nerve [3]. The meaning of this aging-related increase in SREBP-1 in both the PNS ... myelin protein-22, myelin asso- ciated glycoprotein (MAG) and myelin basic protein, but no myelin-specific lipids. Nevertheless, whereas all major lipid classes are present in mye...

Ngày tải lên: 18/02/2014, 13:20

... recall). Detecting problematic turns in human- machine interactions: Rule-induction versus memory-based learning approaches Antal van den Bosch ILK / Comp. Ling. KUB, Tilburg The Netherlands antalb@kub.nl Emiel ... 1997). RIPPER is a fast rule induction algorithm. It starts with splitting the training set in two. On the basis of one half, it induces rules in a straightfor- ward way (...

Ngày tải lên: 23/03/2014, 19:20