Textbook of Interventional Cardiovascular Pharmacology - part 10 pps

... (2,12) of 40 hrs (1); min (7) dose-dependent, 47 hr for 5 mg dose (15) For vitamin K dependent clotting factors: II-60 hr, VII-4–6 hr, IX-24 hr, X-4 8-7 2 hr (1) Return to 4–5 days for INR 10 ... to half-life of anti-Xa activity following SC injection. b The platelet-inhibitory effects of aspirin last the lifetime of the platelet, due to irreversible inactivation of platele...

Ngày tải lên: 11/08/2014, 11:22

... PFM-P75 Pig coronary Ibuprofen 10 15 µg PFM-P75 No art in 5% (g/g) Valsartan 20–25 µg PFM-P75 No in 10% (g/g) De Scheerder (18) 2000 Self-designed PFM-P75 Pig coronary Trapidil 92 µg in PFM-P75 ... control for treat- ment of in-stent restenosis. Circulation 2002. 106 : 109 0 109 6. 36 Baierl V, Baumgartner S, Pollinger B, et al. Three-year clinical follow-up after strontium/yttrium beta...

Ngày tải lên: 14/08/2014, 05:21

... mammalian systems (9 ,10) . Removal of fibrinopeptide A leads to end-to-end fibrin poly- merization whereas loss of fibrinopeptide B allows side-to-side polymerization of the end-to-end linked monomers ... introduction for the Textbook of Interventional Cardiovascular Pharmacology . This definitive international textbook on cardiovascular pharmacology for interventional...

Ngày tải lên: 11/08/2014, 11:22

... product of the lipoxyge- nase pathway, 5-oxo-6,8,11,14-eicosatetraenoic acid (5-Oxo-ETE), induces leukocyte chemotaxis and inflamma- tion. 5-Oxo-ETE is formed by the oxidation of 5S-hydroxy-ETE (5-HETE) ... the presence of a radical H instead of CO 2 CH 3 in the molecule. 2. Clopidogrel (SR 25990) (Plavix ® Sanofi-Aventis) is the hydrogen sulfate salt of the S enanthiomer of methy...

Ngày tải lên: 11/08/2014, 11:22

... 5 ,1 0- methylenetetrahydrofolate, a reaction catalyzed by the vitamin B 6 -dependent enzyme serine/glycine hydrox- ymethyltransferase. 5 ,1 0- Methylenetetrahydrofolate is then reduced to CH 3 - THF ... B 2 (riboflavin)-dependent enzyme 5 ,1 0- methylenetetrahydrofolate reductase (MTHFR), using NADPH as cosubstrate. MTHFR is the key enzyme for diverting 5 ,1 0- methylentetrahydrofolate t...

Ngày tải lên: 11/08/2014, 11:22

... proMMP-2 MT2-MMP MMP-15 Activates proMMP-2 MT3-MMP MMP-16 Activates proMMP-2 MT4-MMP MMP-17 Not known MT5-MMP MMP-24 Activates proMMP-2 MT6-MMP MMP-25 Not known Nonclassified MMPs Matrilysins MMP-7 ... family of peptides (VEGF-A to -E) of which VEGF-A is the most thoroughly stud- ied. VEGF-A (more often called just VEGF) occurs in five isoforms of 121, 145, 165, 189, and 206 amino acids...

Ngày tải lên: 11/08/2014, 11:22

... and low levels of transgene expression limit this approach. Phospholipid formulae such as 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-dode- canoyl/1,2-dioleoyl-sn- glycero-3-phosphocholine ... muscle forma- tion is not the only factor contributing to the positive outcome, and illustrates our lack of understanding of the underlying mechanism(s) of cell-mediated repair. Of particu...

Ngày tải lên: 11/08/2014, 11:22

... CIBIS-II-Investigators-and-Committees. The Cardiac Insuffi- ciency Bisoprolol Study II (CIBIS-II): a randomised trial. Lancet 1999; 353:9–13. 91 Beta-Blocker-Evaluation -of- Survival-Trial-Investigators. ... failure: analysis of the experience in the MERIT-HF study. J Am Coll Cardiol 2001; 38:932–938. 29 The-Beta-Blocker-Evaluation -of- Survival-Trial-Investigators. A Trial of the beta-b...

Ngày tải lên: 11/08/2014, 11:22

... uterine) 8100 10 PDGFRL PDGF-receptor-like 8100 17 PLAUR Plasminogen activator, urokinase receptor 8101 17 ANXA11 Annexin A11 8101 24 PAFAH1B3 Platelet-activating factor acetylhydrolase, isoform 1b, ... low-density lipopro- tein-related protein-1, matrix metalloproteinase 3 gene (MMP3), angiotensin-1 converting enzyme, methylene tetrahydrofolate reductase, Factor VII, P-selectin (SELP, fi...

Ngày tải lên: 11/08/2014, 11:22

... 31% 24 20 10 12 (A) (C) (D) (B) <= –30 <= 10 (0 ,10) (10, 20) (20,30) (30,40) (40,50) (50,60)( 10, 0) <= –30 <= –30 (–30,–20) (–30,–20) (–30,–20) (–20, 10) (–20, 10) (–20, 10) ( 10, 0) ( 10, 0) ( 10, 0) (0 ,10) ... vitro pharmacodynamic profile of the selective Factor Xa inhibitor ZK-807834 (CI -1 03 1). Thromb Res 2002; 105 :347–352. 60 Chu V, Brown K, Colussi D, et al. P...

Ngày tải lên: 14/08/2014, 05:21