Textbook of Interventional Cardiovascular Pharmacology - part 8 doc

... failure: analysis of the experience in the MERIT-HF study. J Am Coll Cardiol 2001; 38: 932–9 38. 29 The-Beta-Blocker-Evaluation -of- Survival-Trial-Investigators. A Trial of the beta-blocker bucindolol ... 332 :80 85 . 90 CIBIS-II-Investigators-and-Committees. The Cardiac Insuffi- ciency Bisoprolol Study II (CIBIS-II): a randomised trial. Lancet 1999; 353:9–13. 91 Beta-Blocker-Evaluatio...

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... systems (9,10). Removal of fibrinopeptide A leads to end-to-end fibrin poly- merization whereas loss of fibrinopeptide B allows side-to-side polymerization of the end-to-end linked monomers (11). ... 273.) xxvi 1 180 FM 3/15/07 6:57 PM Page xxvi Textbook of Interventional Cardiovascular Pharmacology Nicholas N. Kipshidze FACC FESC FSCAI Professor of Medicine and Surgery Con...

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... product of the lipoxyge- nase pathway, 5-oxo-6 ,8, 11,14-eicosatetraenoic acid (5-Oxo-ETE), induces leukocyte chemotaxis and inflamma- tion. 5-Oxo-ETE is formed by the oxidation of 5S-hydroxy-ETE (5-HETE) ... (0.93–1.02) (0 .85 –0.99) (0 .81 –1.03) (0 .83 –0. 98) (0.94–1.03) (1.36–1.97) N ϭ 31,402 NNT ϭ 65 NNT ϭ 99 NNT ϭ 396 NNT ϭ 133 NNT ϭ70 NNH ϭ 87 ( 38 233) ( 58 341) (14 9- ␣ ) (...

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... and low levels of transgene expression limit this approach. Phospholipid formulae such as 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-dode- canoyl/1,2-dioleoyl-sn- glycero-3-phosphocholine ... have a long half-life of elimination 388 Principles of photodynamic treatment 1 180 Chap33 3/14/07 11:40 AM Page 388 intravenous injection of plasmid DNA complexed with synthetic multi-fun...

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... Importance of factor Xa in determining the procoagulant activity of whole- blood clots. J Clin Invest 1993; 91: 187 7– 188 3. 55 McKenzie CR, Abendschein DR, Eisenberg PR. Sustained inhi- bition of whole-blood ... unfractionated heparin, low-dose DX-9065a, or high-dose DX-9065a. The primary end-point was the compos- ite of death, MI, urgent revascularization, or ischemia on continuous...

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... restenosis rate of control arm from the more recent DES trials, a reduc- tion of 81 % of in-stent restenosis and a 42% reduction of late loss, and also represent a reduction of 90% of MACCE. We can ... (%) SIRIUS 9 75 4 75 8 62 E-SIRIUS 5.9 86 4 81 8 64 TAXUS II 11 75 4.7 62 11 50 TAXUS IV 7.9 70 3 73.5 8. 5 43 TAXUS V 19 45 8. 6 45 15 29 ORAR II 12 72 8. 3 75 20 50 Abbr...

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... proMMP-2 MT2-MMP MMP-15 Activates proMMP-2 MT3-MMP MMP-16 Activates proMMP-2 MT4-MMP MMP-17 Not known MT5-MMP MMP-24 Activates proMMP-2 MT6-MMP MMP-25 Not known Nonclassified MMPs Matrilysins MMP-7 ... family of peptides (VEGF-A to -E) of which VEGF-A is the most thoroughly stud- ied. VEGF-A (more often called just VEGF) occurs in five isoforms of 121, 145, 165, 189 , and 206 amino acid...

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... 73.5 1 ,88 8 1,497/ 1,256/ 1,0 28/ 81 1/ 606/ 93.2 88 .0 82 .7 76.6 71.9 514 396/ 360/ 293/ 221/ 171/ 89 .0 84 .4 76.5 68. 8 65.0 No./% (A) (B) P=0 .86 5 P = 0.002 CTO Matched non-CTO CTO-success Matched-success CTO-failure ... 1,145/ 85 9/ 616/ 92.5 88 .0 83 .1 76.3 71.2 2,007 1,601/ 1,347/ 1,104/ 87 9/ 662/ 93.0 87 .9 82 .2 76.4 71.4 CTO Surviving (%) Years CTO-Success...

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... first series of patients. Circulation 1997; 95 (8) :2075–2 081 . 8 Gietzen FH, Leuner CJ, Raute-Kreinsen U, et al. Acute and long-term results after transcoronary ablation of septal hyper- trophy (TASH). ... mean 15–20 8 hr (2,12) of 40 hrs (1); min (7) dose-dependent, 47 hr for 5 mg dose (15) For vitamin K dependent clotting factors: II-60 hr, VII-4–6 hr, IX-24 hr, X-4 8- 7 2...

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... Scheerder ( 18) 2000 Self-designed PFM-P75 Pig coronary Ibuprofen 10–15 µg PFM-P75 No art in 5% (g/g) Valsartan 20–25 µg PFM-P75 No in 10% (g/g) De Scheerder ( 18) 2000 Self-designed PFM-P75 Pig coronary ... Paclitaxel-eluting stents vs vascular brachytherapy for in-stent restenosis within bare-metal 286 Brachytherapy 1 180 Chap23 3/14/07 4: 58 PM Page 286 1 180 Chap20 3/14/07 11:30 AM Pag...

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