báo cáo khoa học: " Ectopic expression of MdSPDS1 in sweet orange (Citrus sinensis Osbeck) reduces canker susceptibility: involvement of H2O2 production and transcriptional alteration" pdf
báo cáo khoa học: " Ectopic expression of MdSPDS1 in sweet orange (Citrus sinensis Osbeck) reduces canker susceptibility: involvement of H2O2 production and transcriptional alteration" pdf
... Open Access Ectopic expression of MdSPDS1 in sweet orange (Citrus sinensis Osbeck) reduces canker susceptibility: involvement of H2O2 production and transcriptional alterationXing-Zheng Fu1,2, ... this article as: Fu et al.: Ectopic expression of MdSPDS1 in sweet orange (Citrus sinensis Osbeck) reduces canker susceptibility: involvement of H2O2 production and transcriptional alteration. ... transforma-tion of a gene involved in polyamine biosynthesis,adding new insight into the functions of polyamines forengineering biotic stress tolerance.ResultsTransformation and regeneration of plants...
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báo cáo khoa học: " Translating research into practice in Leeds and Bradford (TRiPLaB): a protocol for a programme of research" ppsx
... aim of TRiPLaB is to develop, implement, and evaluate methods of inducing and sustaining the uptake of research into practice in order to improve the quality of health services for the people of ... barriersto implementation, and to gain a richer understanding of the influence of health care teams and social networks in the uptake and adoption of new innovations into practice.Quantitative ... at increasing the trans-lation of research findings into clinical and service prac-tice. TRiPLaB aims to play a part in improving the quality of health services for the people of Leeds and...
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báo cáo khoa học: " Gene expression and hypoxia in breast cancer" doc
... Inhibits binding of HIF-1α to the HRE sequence Anthracyclines licensed to treat breast, bladder and lung daunorubicin cancer, several hematological malignancies and sarcomaEchinomycin Quinoxaline ... antibiotic Inhibits HIF-1 binding to DNA Minimal evidence of ecacy in the treatment of solid tumors in phase 2 trials [99]Everolimus mTOR inhibitor Inhibits HIF-1α target protein translation ... 19 kDa protein-interacting protein 3; CAD, carboxy-terminal transactivation domain; CAIX, Carbonic anhydrase 9; CDKN1A, Cyclin-dependent kinase inhibitor 1A; FIH, factor inhibiting HIF; GLUT1,...
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Báo cáo khoa học: "Oxidative stress is increased in critically ill patients according to antioxidant vitamins intake, independent of severity: a cohort study" pptx
... release of cytokines from immune cells, activate inflammatory cascades and increase the expression of adhesion molecules [3]. Inflam-mation and tissue injury result in an accumulation of granulo-cytes ... vitamin con-centrations, increased lipid peroxidation and increased nitriteexcretion, and found an association between plasma LP and Figure 2Worsening in oxidative stress according to intake of ... included patients whose intake of anti-oxidant vitamins was below 66% of RDA (tertile II), and group2 included patients whose intake of these vitamins wasbetween 66% and 100% of RDA (tertile III).The...
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Tài liệu Báo cáo khoa học: Homologous expression of the nrdF gene of Corynebacterium ammoniagenes strain ATCC 6872 generates a manganese-metallocofactor (R2F) and a stable tyrosyl radical (Y•) involved in ribonucleotide reduction ppt
... suggesting thatthe heterologous expression of genes encoding metallo-proteins can lead to incorrect metal ion incorporation.This is observed in rubredoxin and desulforedoxinswhere zinc, instead ... [35] may not be considered in the light of theresults obtained in the present study. Rather, the involvement of manganese in the in vivo assembly of the metallocofactor of C. ammoniagenes R2F is ... R2F in vivo, even in the absence of manganese, and it is the availability of manganese thatis the limiting factor determining the amount of func-tional metalloradical cofactor obtained. In addition,relatives...
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Tài liệu Báo cáo khoa học: Tissue expression and biochemical characterization of human 2-amino 3-carboxymuconate 6-semialdehyde decarboxylase, a key enzyme in tryptophan catabolism pptx
... Picolinicacid in milk, pancreatic juice and intestine: inadequatefor role in zinc absorption. Am J Clin Nutr 35, 1–9.16 Evans GW & Johnson PE (1980) Characterization and quantitation of a zinc binding ... present in kidney and liver, with highest expression occurring in kidney. In brain, no ACMSD II expression is detected, and ACMSD I is present at very low levels. Cloning of the two cDNAs in yeast expression ... with cerebral malaria and in the brain of a murine model of the syndrome[18,19]. Interestingly, picolinate is reportedly able toprevent the neurotoxic effects of quinolinate in the ratcentral...
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Tài liệu Báo cáo khoa học: Differential expression of duplicated LDH-A genes during temperature acclimation of weatherfish Misgurnus fossilis Functional consequences for the enzyme ppt
... Molecu-lar cloning and cold-inducible gene expression of ferritinH subunit isoforms in rainbow trout cells. J Biol Chem271, 26908–26913.13 Tang SJ, Sun KH, Sun GH, Lin G, Lin WW & ChuangMJ ... protein. 1v6a.pdb des-cribes secondary, tertiary and quaternary structures of LDH-A from the skeletal muscle of common carpincluding subunit and ligand interactions. Therefore,the structure of ... affecting rates of transcription and ⁄ or transla-tion and ⁄ or mRNA and protein degradation. Thisrepresents a quantitative strategy to offset the lack orexcess of kinetic energy (as a measure of...
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Tài liệu Báo cáo khoa học: Altered expression of CD1d molecules and lipid accumulation in the human hepatoma cell line HepG2 after iron loading pptx
... ferritin expression in nonpermeabilized (thin lines,– saponin) and permeabilized cells (thick lines, + saponin) cells cul-tured without and with iron as indicated. (D) Perls’ staining of cyto-spins ... further increase in ROS production as deter-mined by an increase in DCFH mean fluorescenceintensity (Fig. 2B, thick line). In addition, determin-ation of acrolein adducts, a marker of oxidative ... coordinatedchanges in the expression of the transferrin receptor and ferritin; (b) developed iron accumulation and (c) increased the prooxidant state and the level of oxidatively modified proteins....
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Tài liệu Báo cáo khoa học: Endogenous expression and protein kinase A-dependent phosphorylation of the guanine nucleotide exchange factor Ras-GRF1 in human embryonic kidney 293 cells pptx
... 25 min prior to 5 min of treatment with10 lm serotonin (Fig. 6B). Increasing the free intracel-lular levels of Ca2+by treatment of HEK293 cells withthapsigargin induced phosphorylation of ... serotonin. Serotonin-induced phos-phorylation of ERK1 ⁄ 2 was markedly reduced in thepresence of 20 lm CAI (Fig. 6A). Serotonin-inducedphosphorylation of ERK1 ⁄ 2 was also reduced in cells incubated ... thedeletion of amino acids 1–225, including the Ca2+⁄ calmodulin-binding IQdomain, from Ras-GRF1 reduced both basal and serotonin-stimulatedERK1 ⁄ 2 phosphorylation. Furthermore, serotonin treatment...
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Tài liệu Báo cáo khoa học: Enhanced expression of Mcm proteins in cancer cells derived from uterine cervix docx
... the findings obtained byhematoxylin and eosin staining. We examined the expres-sion of these proteins in a cancer-free layer of squamousepithelial cells, carcinoma in situ (CIS) and invasive ... Bluestaining.Table 2. Quantitation and comparison of proteins in GM and WI-38cells. From the data in Fig. 2 and others, the concentrations of Mcmproteins, ORC2 and PCNA in total protein and chromatin-bound ... shown). The intensity of the Mcm4band was clearly decreased at 22 h chase in both HeLa and WI-38 cells, indicating the presence of turnover of theprotein. Quantitation of the Mcm4 band suggested...
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