báo cáo khoa học: " Ethylene is involved in pistil fate by modulating the onset of ovule senescence and the GA-mediated fruit set in Arabidopsis" docx

... LE Open Access Ethylene is involved in pistil fate by modulating the onset of ovule senescence and the GA-mediated fruit set in ArabidopsisPablo Carbonell-Bejerano1,2, Cristina Urbez2, Antonio ... among the up-regu-lated genes in the pistil at the onset of ovule senescence further suggests that ethylene plays a role in the process. The onset of ovule senescence in unfertilised pistils is affected ... ovule in modulating the GA response during fruit set in Arabidopsis. A possible mechanism that links the ethylene modulation of the ovule senescence and the GA3-induced fruit set response is...

Báo cáo khoa học: Sin3 is involved in cell size control at Start in Saccharomyces cerevisiae Octavian Stephan and Christian Koch ppt

... by Sin3 in the G1phase. At 160 min, most cells in the cul-ture had left G1 and exhibited no Sin3 binding to the promoter (Fig. 6E). Analysis of G1cyclin expressionshowed that binding of ... activation (Fig. 6B). The timing of Sin3binding is therefore consistent with a role for Sin3 in repression of CLN transcription in the G1phase.ABCDEFGFig. 6. Dissociation of Sin3 from SBF-dependent ... for the speciﬁcity of Sin3 binding, cells not expressing the epi-tope tag were analysed in parallel. Sin3–myc bindingto the promoter sequences of CLN1 and CLN2 wasstrongly reduced in swi4 and...

Báo cáo khoa học: "Age is not a limiting factor for brachytherapy for carcinoma of the node negative oral tongue in patients aged eighty or older" docx

... conceived of this study and drafted manuscript. KY participated in the design of this study. TK and YY participated in the statistical analysis. MK, SF,NK, KS and TN participated in its design and ... agingleads to a diminished reserve capacity and increased vul-nerability to age-related diseases and overall forces of mortality [6-8]. As the effects of aging depend on the individual, they ... increasingsteadily because of advances in both health and medicalcare and the leading cause of death among the elderly is cancer. The number of people aged 80 or over reached7,130,000 in Japan in...

Báo cáo khoa học: "When is a GIST not a GIST? A case report of synchronous metastatic gastrointestinal stromal tumor and fibromatosis" ppt

... With the increasing use of TKI in the treatment of advancedGIST, the pattern of disease evolutions are changingwhich will ultimately impact on the approach to manage-ment.A number of soft tissue ... considered.Background The finding of gain -of- function mutation of KIT has revo-lutionized the treatment of advanced gastrointestinal stro-mal tumor (GIST). This has subsequently led todevelopment of effective ... similarities in the morphological and immunophenotypic profileswith GIST. Aggressive fibromatosis (AF) and keloid typefibromatosis scar tissues are distinct soft tissue tumors. AF is a fibroproliferative...

Báo cáo khoa học: "Continuously assessed right ventricular end-diastolic volume as a marker of cardiac preload and fluid responsiveness in mechanically ventilated cardiac surgical patients" pdf

... resulting increase in SVITD following fluidloading (Fig. 2b). These findings are in accordance with those of other studies [7,13] and emphasize the importance of TEE in detecting acute changes in ... LVEDA index in discriminating responders fromnonresponders [7]. The analysis presented in Fig. 2b shows the considerable influence of two data points correspondingto relative increases in SVI of ... betweenchanges in the remaining preload-indicating variables and ∆SVITD, suggesting that increased cardiac preload is morereliably reflected by CEDV index than by CVP, PCWP, orLVEDA index. Some investigators...

Tài liệu Báo cáo khoa học: "Inducing Gazetteers for Named Entity Recognition by Large-scale Clustering of Dependency Relations" ppt

... thisdata into the training set (9,000 sentences), the de-11Here, we call the value returned by a gazetteer a “class”.Features are not output when the returned class is UNK in the case of the ... storing the training examples. The timecomplexity is mainly O(L × |C| × I), where I is the number of update iterations. The space require-ments are the main limiting factor. Assume that aﬂoating-point ... this further.4.5 Effect of Combining the Cluster and the Wikipedia GazetteersWe have observed that using the cluster gazetteer and the Wikipedia one improves the accuracy of Japanese NER. The...

Báo cáo khoa học: Parkin deﬁciency disrupts calcium homeostasis by modulating phospholipase C signalling pdf

... to determine the link between PKCa and parkin. In view of the vast number of identiﬁed parkin sub-strates [50], the vulnerability to toxic insults in parkinARJP must be a combination of an imbalance ... hydrolysis is enhanced in parkin-deﬁcient cell lines. Histograms show means ± SEM of PI hydrolysis measured in basal conditions of NT, parkin WT, R42P and G328E transfected cells (n = 5) (A) and in the ... lL of chloroform–methanol(1 : 2). Tubes were incubated on ice for 30 min and the phases were separated by the addition of 310 lL of chloro-form and 310 lL of water, followed by vortexing and centrifugation;...

Báo cáo khoa học: hhLIM is a novel F-actin binding protein involved in actin cytoskeleton remodeling ppt

... signaling, and division. Many of the actin-binding proteins affect the cytoskeletal structure and architecture by mediating the association of actin ﬁlaments into cables and bun-dles and cross-linking ... by hhLIM and CRPs requires, in the ﬁrst instance, identi-ﬁcation of their actin-binding domains. To date, none of the actin-binding domain sequences registered in databases is present in hhLIM ... CRPs. The goals of this study were to deﬁne the actin-binding properties of hhLIM and determine the precise actin-binding sites of hhLIM. Our results show that hhLIM binds to ﬁla-mentous (F) actin...

Tài liệu Báo cáo khoa học: NirF is a periplasmic protein that binds d1 heme as part of its essential role in d1 heme biogenesis pdf

... and of the kanamycin insertion mutant nirF strain(SBN03) in the upper right panel. Growth of SBN11 (DnirF) is shown in the bottom leftpanel and of SBN13 (DnirF) containingpEG276-nirF in the ... His200 of P. pantotrophus NirS is conservedbetween NirF and NirS; it is the His residue that in NirS is the proximal axial ligand to the d1heme.Replacement of an equivalent His, His41, in ... in NirF by Ala abolished binding of the heme to the protein.Known distal heme-binding residues, such as Met, Lysor Cys [18,19], were substituted for His41 in NirF. Nochanges in the visible...

Báo cáo khoa học: Visfatin is induced by peroxisome proliferator-activated receptor gamma in human macrophages pdf

... wereabolished when insulin receptor signalling was blocked[8], in line with the report that visfatin could bind and activate insulin receptors [14]. However, the insulin-mimetic actions of visfatin ... dataAcLDL12Visfatin/cyclophilin mRNAVisfatin/cyclophilin mRNAVisfatin/cyclophilin mRNACD36/cyclophilin mRNAFABP4/cyclophilin mRNAVisfatin/cyclophilin mRNAVisfatin/cyclophilin mRNAVisfatin/cyclophilin ... PPARcligands increase NAD+production in primary human macrophages and that this regulation is dampened in the presence of visfatin small interferingRNA or by the visfatin-speciﬁc inhibitor FK866....

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