Báo cáo y học: "Immunostimulatory effects of three classes of CpG oligodeoxynucleotides on PBMC from HCV chronic carriers" pot

... pre-existing Th2 responses [33]. CpG properties vary depending on length, sequence, backbone and formation of secondary or tertiary struc- tures. Three main classes of stimulatory CpG are described [34]. ... and Vaccines Open Access Original research Immunostimulatory effects of three classes of CpG oligodeoxynucleotides on PBMC from HCV chronic carriers...

Ngày tải lên: 11/08/2014, 10:23

... were treated with the Poly [ADP-ribose] polymerase (PARP) inhibitor ABT-888 (final concentration 5µM) Recombinatory chemistry of the fusion plasmid The construction of the pKillerRed-Lamin ... impact on aging as well as diseases which are associated with mitochon- drial DNA mutations are discussed [11-15]. The connection between ROS activity and cellu- lar toxicity is beyond cont...

Ngày tải lên: 25/10/2012, 11:15

... analogs on the thermotropic phase behavior of LMVs composed of dimyristoylglycerophosphocholine (Myr 2 Gro-PCho), dimy- ristoylglycerophosphoethanolamine (Myr 2 Gro-PEtn) and dimyristoylglycerophosphoglycerol ... rmcelhan@gpu.srv.ualberta.ca Abbreviations: GS, gramicidin S; Myr 2 Gro-PCho, dimyristoylglycerophosphocholine; Myr 2 Gro-PEtn, dimyristoylglycerophosphoethanolamine; Myr 2 Gro...

Ngày tải lên: 21/02/2014, 01:21

... existence of a POR- phosphatase is the observation by Wiktorsson et al. [9] of an inhibition, by NaF and ATP, of the loss of the long- wavelength form of Chlide following photoconversion of reformed ... these conditions, hence the lack of reformation of POR-PChlide 650 . Addition of low concentrations of NADPH to PLB aged at pH 7.5 which show only limited structural reorga...

Ngày tải lên: 22/02/2014, 04:20

... constitutes the bulk of the fatty acid at the sn-2 position of 1-alkyl-2-acyl-GPC under resting conditions [70]. Upon cell activation, most of this AA is replaced by other fatty acids. Finally, ... activation is accompanied by an increase in PAF biosynthesis via acetylation of 1-alkyl-2-lyso-GPC by acetyl transferase (Fig. 8, f) activity, competition for 1-alkyl-2-lyso-GPC intermediat...

Ngày tải lên: 22/02/2014, 07:20

... efficiency of tyrosine sulfation may d epend on additional signals [44] and/or accessability to the modifying enzyme. HCII from CHO cells incubated with i nhibitors of post-translational modifications ... whereas only about 10% of the serum protein showed fucosylation of the diantennary and triantennary N-glycans. Approximately 60% of the trian- tennary structures is olated from...

Ngày tải lên: 08/03/2014, 22:20

... cell cycle The effects of various concentrations (0.05, 0.1, and 1 mg/mL) of the three kinds of MNPs on cell cycle pro- gression and population distribution in BEL-7402 cells were determined by flow ... observed by transmission electron microscopy (TEM) and cell viability was determined by tetrazolium salt-based (WST-1) assay. For the study of the mechan- ism of cytotoxicity,...

Ngày tải lên: 21/06/2014, 01:20

... 15–24 Immunostimulatory effects of anionic alkali mineral complex solution Barodon in porcine lymphocytes Byung Woo Yoo, Soo Il Choi 1 , So Hyun Kim 2 , Soo Jin Yang 2 , Hye Cheong Koo 2 , Sang Hoon Seo, Bong Kyun ... effec- tiveness as a nonspecific immunostimulator in pigs. The effects of Barodon were determined by analysis of feed efficiency, growth rate, and phenotype of leuko...

Ngày tải lên: 07/08/2014, 14:23

... included inhibition of white blood cell infiltration, stimulation of glycosaminoglycan release and nitric oxide production, and induction of fibrogenesis and muscle edema. In addition, induction of chondrogenesis ... previously examined the effects of TGF-β1 gene transfer on matrix synthesis in chondrocyte cultures, demonstrating a significant stimula- tion in the production of...

Ngày tải lên: 09/08/2014, 01:21

... then calculated chondron area. An average of 24 chondrons (range ± 13) that contained cells (usually only one cell per chondron) were counted from each image, and empty chondrons were counted separately to ... M2139 (dark grey) over the course of 21 days. (b) The number of empty chondrons expressed as a percentage of the total number of chondrons, indicating the loss of chondro...

Ngày tải lên: 09/08/2014, 06:23