Báo cáo y học: "Induction of cystine/glutamate transporter in bacterial lipopolysaccharide induced endotoxemia in mice" docx

... SH, Min SY, Bae EY, Lee WK, Hwang SY, Park SH, Cho CS, Kim HY: Suppres- sion of collagen induced arthritis by single administration of poly(lactic-co-glycolic acid) nanoparticles entrapping CII: ... are involved in the induction of peripheral tolerance in an orally tolerized mouse model of arthritis. Our findings indicate that the serum levels of pro- inflammatory and anti-inf...

Ngày tải lên: 09/08/2014, 01:23

... protein of HCV can signal extracellularly and that naked core protein is present in the serum of infected individuals [17]. To examine the role of soluble core protein in cytokine sign- aling in ... characteristics of HCV core protein described in our studies may be of key importance to clin- ical infection. Individuals with chronic HCV infection have evidence of upregulat...

Ngày tải lên: 12/08/2014, 18:22

... mechanism of metronidazole neu- rotoxicity. It has been suggested that metabolites of metronidazole may bind to RNA instead of DNA, possi- bly inhibiting RNA protein synthesis, which could potentially ... encephalopathy. In each of the cases we reviewed, including ours, there was symmetrical increase of T2 signal intensity and absence of mass effect and enhancement. Reversible c...

Ngày tải lên: 11/08/2014, 00:22

... supply of cysteine to the lymphocytes by the vicinal cells, although we cannot rule out the possibility that the activity of sys- tem xc- is induced in the lymphocytes in vivo. The activity of system ... demonstrated previously that spleen lymphocytes have hardly detecta- ble activity of system x c - regardless of the activation by LPS in vitro [17]. The supply of cystein...

Ngày tải lên: 11/08/2014, 08:21

... (2–5)A pathway is also induced by interferons [15]. The major enzyme in this pathway, the (2–5)A synthetase catalyzes the synthesis of a series of 2¢)5¢- linked oligoadenylates, termed (2–5)A ... again. Higher concentrations of LPS (10 lgÆmL )1 ) caused a lower effect on the (2–5)A synthesizing activity in S. domuncula. Despite the initially high (2–5)A synthesizing activity in...

Ngày tải lên: 21/02/2014, 15:20

... es, B.J. (1992) Interaction of m urine ets-1 with GGA-binding sites establishes the ETS domain as a new D NA-binding motif. Genes Dev. 6, 975±990. 10. Wasylyk, C., Kerckaert, J.P. & Wasylyk, B. (1992) ... (at least in Ets-1 and Ets-2) of an auto- inhibitory domain w hich, in t he absence of a ccessory factors, prevents Ets-1 binding to DNA [ 10,17]. W hen this d omain i s remove...

Ngày tải lên: 17/03/2014, 17:20

... immunoassay of insulin. J. Clin. Endocrinol. Metab. 25, 1375±1384. 16. Chomczynsky, P. & Sacchi, N. (1987) Single step method of RNA isolation by acid guanid inium thiocy anate-phen ol-chloroform extraction. ... mitochondrial protein transporter of adenine nucleotides than adult animals. The lack of responsiveness of fetal b cells in releasing insulin in the presence of...

Ngày tải lên: 31/03/2014, 15:20

... background. Figure 4 Role of B cells in the pathology of G6PI -induced arthritisRole of B cells in the pathology of G6PI -induced arthritis. The role of B cells in the pathology of glucose-6-phosphate ... useful in investigating ankylosing spondylitis because it generates inflammation of vertebral joints followed by ankylosis after a single round of immunization. Ca...

Ngày tải lên: 09/08/2014, 07:20

... Internal Medicine, Division of Rheumatology, University of Pisa, Via Roma 67 - 56126 PISA Italy 2 Department of Psychiatry, Neurobiology, Pharmacology and Biotechnology, University of Pisa, Via ... [ 3 H]Imipramine binding sites are decreased in platelets of chronic pain patients. Clin Neuropharmacol 1987, 10:175-177. 40. Mellerup ET, Plenge P, Engelstoft M: High affinity binding...

Ngày tải lên: 09/08/2014, 08:22

... tissue, including the lining layer and lymphocyte infiltrates. Colocalisation analysis revealed that the CD68 + synovial lining layer contained a large number of cells stained intensely for IL-10R1, ... expression of TNF receptor in lining macrophages in the inflamed ST of RA. Microarray analysis of IL-10 -induced gene expression in RA monocytes To further elucidate the roles...

Ngày tải lên: 09/08/2014, 08:22