Báo cáo khoa hoc:" Editorial: Journal of Negative Results in Biomedicine" ppt

... Journal of Negative Results in BioMedicine 2002, 1 http://www.jnrbm.com/content/1/1/2 Page 2 of 2 (page number not for citation purposes) Mendel, that the branch of biology known ... to a reassessment of the properties of such reagents. Common examples are the reassessment of antibody specificity, the origin of a cell line, or the sequence of a DNA probe. Finally, we b...

Ngày tải lên: 11/08/2014, 08:20

... family of protein tyrosine kinases. These kinas- es result in the increased tyrosine phosphorylation of multiple macrophage proteins and the activation of phospholipase D [82]. Activation of protein ... generation of opsonically active C3b in the absence of early activation components [23]. Individual strains of M. tuberculosis can vary in their modes of interaction with...

Ngày tải lên: 16/02/2014, 15:20

... or without hematoxylin staining. In hypoxia experiments, 3T3-L1 cells were maintained in a hypoxia chamber (Invivo 400; Ruskinn Inc., Cincinnati, OH, USA) constantly maintained at 1% O 2 . Culture medium ... cultured in DMEM containing 10% fetal bovine serum. OP9 cells were grown in aMEM containing 20% fetal bovine serum. C2C12 cells were maintained in DMEM containing 10% fetal bovi...

Ngày tải lên: 18/02/2014, 08:20

... interact with a number of functional groups, including the aromatic side chains of some amino acids, through a stacking mechanism [42]. The interaction of arginine with aromatic amino acids of aB-crystallin ... state). In con- trast, arginine has been shown to suppress aggregation of some proteins by acting on the unfolded state of the protein and increasing the reversibility o...

Ngày tải lên: 18/02/2014, 16:20

... detected at the dimer interface of the models or in the surroundings of the hinge loop residues. Likewise, the models of nonex- changing and exchanging HHP-RNase were prepared start- ing from 1Z7X. ... strong, neutralizing action of the cytosolic RNase inhibitor (cRI), a 50-kDa protein containing 16 leu- cine-rich repeat motifs [7,8]. In fact, onconase from Rana pipiens eggs [9],...

Ngày tải lên: 19/02/2014, 06:20

... extension to the protein kinase folds back on the kinase domain and interferes with the substrate binding sites. In the case of the titin and twitchin kinases, the autoinhibitory sequence acts ... hexadecameric enzyme consisting of four copies of four subunits: (abcd) 4 . An intrinsic calmodulin (CaM, the d subunit) binds directly to the c protein kinase chain. The interaction site o...

Ngày tải lên: 19/02/2014, 17:20

... substrate binding process. This provides strong evidence that N-glycans, in particular their terminal structures, are involved in regulating the GABA translocation of GAT1, but not in binding of GAT1 ... not the terminal trimming of N-glycans is involved in the regulation of the stability and trafficking of GAT1. It has been reported that a variety of molecular chaperones a...

Ngày tải lên: 19/02/2014, 17:20

... the training data to measure the impact of each of the four subsets of features explained in Section 3. Ta- ble 3 shows the cross validation results when cu- mulatively adding each set of features. ... features including negative pre- fixes and binary tf-idf features primarily increased performance on the absent class. Using document frequency to prune lexical features showe...

Ngày tải lên: 20/02/2014, 05:20

... Y  ) 326 N N = 2048 N = 128 N = 64 N = 2048 331 Proceedings of the 47th Annual Meeting of the ACL and the 4th IJCNLP of the AFNLP, pages 324–332, Suntec, Singapore, 2-7 August 2009. c 2009 ACL and AFNLP 1

Ngày tải lên: 20/02/2014, 07:20

... eosin staining. We examined the expres- sion of these proteins in a cancer-free layer of squamous epithelial cells, carcinoma in situ (CIS) and invasive cancer, all of which were observed in ... blotting using anti-Mcm2, 3, 4, 5, 6 and 7 Ig (Fig. 1). On comparing the amounts of Mcm in total cellular proteins and chromatin-bound proteins, approximately one-third of total Mcm...

Ngày tải lên: 20/02/2014, 23:20