Báo cáo khoa hoc:" Histopathological grading of pediatric ependymoma: reproducibility and clinical relevance in European trial cohorts" pps

... 10 of 13 RESEARC H Open Access Histopathological grading of pediatric ependymoma: reproducibility and clinical relevance in European trial cohorts David W Ellison 1* , Mehmet Kocak 2 , Dominique ... (OS) in four European trials.(a)PFSand(b) OS by trial. Black line = SFOP; red line = CNS9204; blue line = CNS9904; and green line = AIEOP. Ellison et al . Journal...

Ngày tải lên: 11/08/2014, 07:21

... formation, indicating that Sec14p and the two homologues act as inhibitors of Plb1p in vivo. This observation explains at least in part the low Plb1p activity in wild-type cells. Interestingly, the inhibitory ... temperature of 37 °C [3]; and (b) cki1 prevents reincorporation of the majority of released free choline into PtdCho via the CDP-choline pathway [6]. On the other h...

Ngày tải lên: 23/03/2014, 18:20

Ngày tải lên: 07/08/2014, 18:21

... process of planning, produc- ing, disseminating, and applying existing or new research in decision-making" [44]. Using these definitions, both agencies have established key funding directives ... that remains between research knowledge and healthcare practice. Indeed, the transla- tion of basic scientific knowledge into clinical studies and the translation of clinical s...

Ngày tải lên: 11/08/2014, 05:22

... examination research to highlight the complexity and intricacy of interpreting research in a manner that guides clinical decisions, particularly when research calls accepted clinical practices into ... translation of basic scientific 'bench' discoveries into clinical studies and the translation of clinical studies into improvements in health care practices rema...

Ngày tải lên: 11/08/2014, 16:20

... Calandra T, Cohen J, International Sepsis Forum Definition of Infection in the ICU Consensus Conference: The international sepsis forum consensus conference on definitions of infection in the intensive ... of early changes taking place in the clinical setting of a septic host is of prime importance in order to understand the underlying pathogenesis. The majority of clini...

Ngày tải lên: 13/08/2014, 03:20

... appearance of ulcer edges. Figure 2 Marjolin’s ulcer with sinuses extending into the thigh and labia majora. One sinus was found in the anus, and another in the vagina. Note benign appearance of ulcer ... implantation, the co-carcinogen and the initiati on and promotion the- ory; these theories include trauma as an integral part of the process of the evolution of Marjoli...

Ngày tải lên: 09/08/2014, 03:23

Ngày tải lên: 07/08/2014, 18:21

... enrichment in iNOS activity within the particulate fraction of epithelial cells. Apical distribution of iNOS in intestinal epithelial cells To get more insight into the localization of iNOS in intestinal ... distribution of iNOS protein and activity in vitro The distribution of iNOS protein in the cytosol and particulate fraction was examined in DLD-1 cells exposed t...

Ngày tải lên: 19/02/2014, 16:20

... Llinas M (1988) Lysi- ne ⁄ fibrin binding sites of kringles modeled after the structure of kringle 1 of prothrombin. Proteins 3, 85–96. 20 Thorsen S (1975) Differences in the binding to fibrin of native ... in plasmin formation, to a decrease in plasmin binding or to a combination of the two. We demonstrate that both mAb 34D3 and mAb A10.2 inhibit plasmin binding to cells (Fig...

Ngày tải lên: 20/02/2014, 01:20