Báo cáo khoa hoc:" Evidence against PALB2 involvement in Icelandic breast cancer susceptibility" pot

... citation purposes) Journal of Negative Results in BioMedicine Open Access Brief report Evidence against PALB2 involvement in Icelandic breast cancer susceptibility Haukur Gunnarsson 1 , Adalgeir ... purposes) breast cancer families in Finland, resulting in a 4-fold increased risk to mutation carriers [6]. Although predis- posing PALB2 mutations generally appear t...

Ngày tải lên: 11/08/2014, 07:20

... GTP/GDP-binding protein which functions as a molecular switch in a large network of signaling pathways [1]. Mutations in the ras gene have been identified in about 30% of all human cancers, indicating ... lactacystin [27] were analysed by Western blotting. As can be seen in Fig. 3A, accumulation of the 32-kDa protein, corresponding to the single-chain aD11-sec, was induced by treatment...

Ngày tải lên: 21/02/2014, 00:20

... K m (Eqn 9) fitting were obtained leaving all unknown parameters (i.e. K B1 and K B2 ) floating. CAD: k c (Eqn 5) fitting was obtained leaving all unknown parameters float- ing; in the fitting of K m (Eqn ... underlying substrate selectivity still remain to be discovered. With this in view, we examined the kinetic behaviour of pea seedling amine oxidase with cadaverine and hexylamine, the first...

Ngày tải lên: 06/03/2014, 00:21

... by trying different machine learning methods; includ- ing the user’s dialogue act types as input features; and testing these methods in new domains. 8 Acknowledgments The work reported in this ... the airline itinerary is indicated by 1, and completion of both the airline itinerary and ground arrangements, such as car and hotel book- ings, is indicated by 2. We also defined a binary ver- s...

Ngày tải lên: 08/03/2014, 07:20

... are intro- duced in the text. The existing approach for correcting the spelling error in the languages that have no word boundary assumes that all substrings in input sentence are error strings, ... words in text is harder than in English because of additional ambiguities in locating er- ror words. The traditional method handles this by hypothesizing that every substrings...

Ngày tải lên: 23/03/2014, 19:20

... features. In Proceedings of COLING-ACL-2006. Zhu Zhang. 2005. Mining Inter-Entity Semantic Relations Using Improved Transductive Learning. In Proceedings of ICJNLP-2005. Shubin Zhao and ... This results in a high-quality annotation file. More details can be found in the documentation of ACE 2005 Multilingual Training Data V3.0. Since the final release of the ACE training cor...

Ngày tải lên: 24/03/2014, 03:20

... heterologously expressed as C-terminally His6-tagged apoproteins in E. coli, purified and tested for PCB-binding, apopro- tein folding, Pr–Pfr photochromicity and thermal reversion using SDS ⁄ PAGE ⁄ zinc fluorescence ... mod- ule (the N-terminal chromophore binding PAS ⁄ GAF domains), the missing PHY domain precluding the for- mation of bona fide Pfr. There may also be other prob- lems in e...

Ngày tải lên: 30/03/2014, 11:20

... membrane-mediated plasminogen activation and impair laminin degradation by plasmin. Our data pro- vide evidence that MMP-3 can inhibit breast tumour cell invasion in vitro by a mechanism involving plasminogen degradation ... either 0.1% gelatin, 0.1% casein or 0.1% casein plus 5 lgÆmL )1 plasminogen. Following electrophoresis, gels were washed in 2% triton X-100, rinsed in water and...

Ngày tải lên: 31/03/2014, 09:20

... from invasive ductal breast cancer: an uncommon finding Xiao-Jiao Liu 1 , Peng Shen 2* , Xin-Feng Wang 2 , Ke Sun 3 , Fei-Fei Sun 2 Abstract Background: Invasive ductal carcinoma (IDC) of the breast ... Pylkkänen L, Joensuu H: Invasive lobular carcinoma of the breast has better short- and long-term survival than invasive ductal carcinoma. Br J Cancer 1997, 76:1234-1240. 2. Borst MJ,...

Ngày tải lên: 09/08/2014, 03:21

... useful in OBS for central quadrant tumors involving the nipple (Figure 2). The inferior pedicle is easier and safer and in OBS can be used in tumors situa ted in al l othe r quadrants of the breast ... cosmetic sequelae, a reduction in the size of her breasts offering a medium size left breast to the radiotherapist and reliev - ing such symptoms as neck pain and, finally, an imp...

Ngày tải lên: 09/08/2014, 03:22