Báo cáo y học: "The QICKD study protocol: a cluster randomised trial to compare quality improvement interventions to lower " pot

... for citation purposes) Implementation Science Open Access Study protocol The QICKD study protocol: a cluster randomised trial to compare quality improvement interventions to lower systolic BP ... consent to participate. 4. Agreement to participate in whichever arm of the study they are randomly allocated. 5. Practice has had the same computer system for the...

Ngày tải lên: 11/08/2014, 05:21

... therapist’s experience with internet-based therapies. Data analysis SPSS 17.0 for Windows was used for all analyses. In preliminary analyses, we compared the online and face -to- face group at ... 10 study coordinator and was not stratified by any participant characteristics. Seven (22%) participants in the online group and two (7%) participants in the face -to- face group failed...

Ngày tải lên: 11/08/2014, 16:21

... schizophrenia [19], we promoted total symptom score as a co-primary outcome measure. Finally, early data demonstrating lower levels of attendance at groups than we anticipated led us to increase the total number ... we planned to randomise 376 participants, 94 at each centre. Statistical analysis All primary statist ical analys is will use the intention -to- treat principle. T he sta...

Ngày tải lên: 11/08/2014, 16:22

... 80 kDa at 180 l M , to just under 100 kDa at 1300 l M . A qualitative analysis of these data indicates that the apparent molecular mass at low protein concentrations approaches that of a monomer, ... the conformational changes in arrestin that lead to activation are unknown. Small-angle X-ray scattering (SAXS) was used to investigate the solution structure of arrestin and characteri...

Ngày tải lên: 22/02/2014, 07:20

... activity. This interaction potentially allows a crosstalk between cAMP pathways and ras-mediated pathways in cell cycle control. In addition to its many roles as an intracellular messenger, cAMP also ... counterparts. Despite this overall similarity between mammalian and trypanosomal regulatory subunits, the trypanosomal homo- log binds cGMP rather than cAMP, and the trypanosomal PKA is a...

Ngày tải lên: 31/03/2014, 23:20

... lymphopaenia, thrombocytopaenia, and homogeneous antinuclear antibodies characterized as anti-DNA antibodies. At the time of splenectomy the patient had detectable antibodies against DNA (Crithidia ... was followed by incubation with rabbit anti-mouse IgG (DAKO A/ S), and an alkaline phosphatase/anti-alkaline phosphatase complex (DAKO A/ S). Immune complexes containing alkaline phos- phatas...

Ngày tải lên: 09/08/2014, 01:21

... study, Crabp2 was found to be elevated in DJD in a rat model of OA [29,30]. We found Crapb2 to be significantly increased in early OA, indicating that the retinoic acid pathway may play a role ... Lapadula G, Nico B, Cantatore FP, La Canna R, Roncali L, Pipitone V: Early ultrastructural changes of articular cartilage and syn- ovial membrane in experimental vitamin A- induced osteoar...

Ngày tải lên: 09/08/2014, 01:22

... belongs to a category that bears many of the hall- marks of 'classic' caspase-dependent apoptosis, but also to other categories such as cytoplasmic vacuolization more often associated ... were sequenced using an ABI PRISM Big Dye terminator ready reaction kit (Applied Biosystems, Warrington, UK) and were analysed on a 3700 DNA Analyser (Applied Biosys- tems). Nucleotide and...

Ngày tải lên: 09/08/2014, 06:22

... Although they were initially reported to be specifically associated with systemic lupus erythematosus [7], a later study showed that auto- antibodies to the Su antigen are found in a variety of systemic rheumatic ... molecular modifications. The diversity of autoantibody specificities and their association with particular diseases may be related to the combination of genetic and e...

Ngày tải lên: 09/08/2014, 08:22