báo cáo khoa học: "Nanofibers and nanoparticles from the insectcapturing adhesive of the Sundew (Drosera) for cell attachment" ppsx
... 147 cells/ mm 2 for the negative control, 1681 cells/mm 2 for the positive control, and 1253 cells/mm 2 for the Sundew adhesive coated surface. Due to the non-uniformity i n the coating of the Sundew ... nanofiber and nanoparticle based nanocomposite from the adhesive of Sundew can be used for tissue engineering, and opens the possibility for fu...
Ngày tải lên: 11/08/2014, 00:22
... traffic and ⁄ or degradation of the IR. How- ever, despite a recent report showing the involvement of Grb10 in the ubiquitination and proteasomal degra- dation of the IR in transfected cells [37], there ... inhibits the tyrosine kinase activity of the IR [7]. On the basis of the crystal structure of the tyrosine kinase domain of the IR in complex with the...
Ngày tải lên: 18/02/2014, 18:20
... changes in the extent to which the binding of allosteric ligand modifies the affinity of enzyme for substrate. The Hanes–Wolf plot in Fig. 3(B) conclusively demon- strates that the K m value for Mg.ATP ... heart and leg muscle [12]. In the case of leg muscle, the con- centration of the potent activator, F2,6P 2 , decreased from a level five times the K a value i...
Ngày tải lên: 19/02/2014, 16:20
báo cáo khoa học: "Naturally occurring nanoparticles from English ivy: an alternative to metal-based nanoparticles for UV protection" doc
... adhesive effect of these nanoparticles will allow the ivy nanoparticles to remain on the skin for a longer period of time, and thus enhance their UV protective effect. The combination of these unique ... penetrate through the SC layer [44]. Therefore, to understand ivy nanoparticle diffusion and penetration in human skin, it is essential to understand the diffusion...
Ngày tải lên: 11/08/2014, 00:22
Tài liệu Báo cáo khoa học: P25a ⁄ TPPP expression increases plasma membrane presentation of the dopamine transporter and enhances cellular sensitivity to dopamine toxicity pptx
... Determination of V max and K m for DAT, NET and SERT in the presence and absence of p25a. HEK-293-MSR cells were tran- siently transfected with DAT, NET or SERT and with p25a or mock vector. The cells ... in the central core and were similar to those required for vesicle binding. Co-expression of p25a and the dopamine transporter in HEK-293-MSR cells sensitized t...
Ngày tải lên: 14/02/2014, 21:20
Tài liệu Báo cáo khoa học: Neuronal growth-inhibitory factor (metallothionein-3): evaluation of the biological function of growth-inhibitory factor in the injured and neurodegenerative brain pdf
... neurodegenerative disease. Synthesis and secretion of GIF in the brain Cellular and temporal localization of GIF synthesis Whilst the MT1 and MT2 isoforms are ubiquitously synthesized throughout most ... MT isoform has different and distinct functions within the brain. Furthermore, the discovery and continued investigation of this brain-spe- cific MT isoform has led to...
Ngày tải lên: 16/02/2014, 15:20
Tài liệu Báo cáo khóa học: Quantitative analysis, using MALDI-TOF mass spectrometry, of the N-terminal hydrolysis and cyclization reactions of the activation 2 process of onconase pdf
... almost linear and can be obtained by calculating the slope of the curves of Pyr-ONC (M23L) vs. time. From the rates of cyclizationshowninTable1,itcanbeinferredthatthe formation of the N-terminal ... analyzed by MALDI-TOF MS. The addition of the protease is considered the zero time point. The relative intensities of the peaks from the mass spectra were use...
Ngày tải lên: 19/02/2014, 12:20
Báo cáo khoa học: Adenylyl cyclase Rv0386 from Mycobacterium tuberculosis H37Rv uses a novel mode for substrate selection ppt
... [31]. The substrate specificity of Rv0386 may be deter- mined by the concentrations of available ATP and GTP at the cellular location of the enzyme, yet the intracellular concentrations of ATP and ... analogy to the Rv0386 (1)175) N106D mutant we also generated Rv0386 (1)175) Q57E. On the one hand the mutation eliminated the hydrogen-bond donor property of the...
Ngày tải lên: 07/03/2014, 21:20
Báo cáo khoa học: Apoptosis and autophagy: BIM as a mediator of tumour cell death in response to oncogene-targeted therapeutics pptx
... as a monotherapy [38] highlight the need for a greater understanding of how these compounds act to initiate cell death, which could guide the selection of suitable therapeutic partners for combination ... (PKCs). Treatment of multiple myeloma cells with UCN-01 alone resulted in the activation of ERK1 ⁄ 2 and in the phosphorylation and loss of BIM EL ; however, co-a...
Ngày tải lên: 16/03/2014, 00:20
Báo cáo Y học: Propionate CoA-transferase from Clostridium propionicum Cloning of the gene and identi®cation of glutamate 324 at the active site pdf
... structures i s the lack of a subdomain formed by two b sheets and one a helix connecting the bsheet 2 of the b subunit, which carries the catalytic glutamate, with the inner l ayer of a helices ... 553 Da and a n isoelectric point of 4.9 1 was predicted for the encoded p rotein. B oth values w ere in agreement with the observed molecular mass and the elution o...
Ngày tải lên: 17/03/2014, 17:20