... chelators may also beacting intracellularly, inhibiting Fe incorporation intoferritin. In comparison, the proportion of59Fe in ferritindid not change significantly in the Fe mobilization studies,although ... However,changes in the intracellular distribution of Fe (Table 2),with a big increase in the proportion of Fe in the cytosolsuggest that all the chelators including DFO and DFP, act in part intracellularly, ... line, McA-RH 7777 (McArdleLaboratory for Cancer Research, Wisconsin) was grown in MEM containing 100 lgÆmL)1streptomycin, 3.75 lgÆmL)1Fungizone, 100 UÆmL)1penicillin and 10% fetal bovineserum,...