báo cáo khoa học: " Silver nanoparticles inhibit VEGF-and IL-1 -induced vascular permeability via Src dependent pathway in porcine retinal endothelial cells" potx

... and IL-1 increase endothelial cell permeability via Src dependent pathway. Silver nanoparticles were found to block VEGF- and IL-1 -induced permeability in retinal endothelial cells from porcine ... activity in VEGF-and IL-1 -induced endothelial cell permeabilityFigure 6 Role of Src kinase activity in VEGF-and IL-1 -induced endothelial ce...

Ngày tải lên: 11/08/2014, 00:22

... with (A) fusion inhibitor (Tak- 779, 2 μM), (B) RT inhibitor (AZT, 20 μM), (C) protease inhibitor (Indinavir, 0.25 μM), and (D) integrase inhibitor (118-D-24, 100 μM). Dashed lines indicate the ... contributing in wound healing in vivo [53]. The development of inflammatory process in cervical tissue helps activation of innate defenses against i nvading microbes. These changes during inf...

Ngày tải lên: 11/08/2014, 00:23

... by a three- to sevenfold increase in 6PG and a slight tendency to an increase in NADPH in the Gsd11 strain. It is possible that PPP flux is increased in the Gnd20 strain and that a higher G6PDH ... or nitrate containing media), which should make it relatively robust. In addition, the variables in these eight samples were in most cases determined as averages of several independent...

Ngày tải lên: 07/03/2014, 17:20

... chelators may also be acting intracellularly, inhibiting Fe incorporation into ferritin. In comparison, the proportion of 59 Fe in ferritin did not change significantly in the Fe mobilization studies, although ... However, changes in the intracellular distribution of Fe (Table 2), with a big increase in the proportion of Fe in the cytosol suggest that all the chelators including DF...

Ngày tải lên: 20/02/2014, 11:20

... (MAPK), protein kinase C and PI3 kinase. All values are means ± SD of 3–6 independent experiments run in triplicate. (A) Signaling pathway inhibitors Concentration Reduction of inhibitory effect ... presence of the inhibitors for the kinases cal- cium ⁄ calmodulin -dependent protein kinase (CaMKII), extracellular signal-regulated kinase 1 ⁄ 2 (ERK1 ⁄ 2), p38 mitogen-activated pro- tein k...

Ngày tải lên: 07/03/2014, 12:20

... remaining in the matrix at different times in culture was determined [9]. Measurement of incorporation of [ 3 H]serine into macromolecules by tendon maintained in culture in medium containing ... the amounts of glycosaminoglycans remaining in the matrix. Measurement of turnover of 35 S-labeled proteoglycans in tendon maintained in culture in medium containing varying concentra...

Ngày tải lên: 23/03/2014, 10:21

... starting at 300 °C and Fig. 5 HR-TEM images of the Ag/pyr sample. The graphitic layers can be seen surrounding the individual silver nanoparticles, thus forming a carbon matrix where the nanoparticles ... encapsulated. In the last image a single silver nanoparticle and its typical interlayer spacing is shown in magnification 1362 Nanoscale Res Lett (2009) 4:1358–1364 123 characteriz...

Ngày tải lên: 22/06/2014, 00:20

... allowed to interact for 10 minutes. Thereafter, CMC was added and allowed to interact for 20 minutes before adding PDDA, which was also allowed to interact for 20 minutes, before determining zeta-average ... PL (Table 2). At high P, the effect of increasing PL molecular weight was an increase in size, an increase in zeta-potential and a decrease of % of cell viability (Table 2). Table 1 s...

Ngày tải lên: 11/08/2014, 00:22

... facilitate bone healing by using PLGA nanoparticles containing therapeutic genes such as bone morphogenic protein. Nanoparticles for drug delivery into the brain: The blood-brain barrier (BBB) ... Polynucleotide vaccines/DNA vaccines/plasmid vaccines work by delivering genes encoding relevant antigens to host cells where they are expressed, producing the antigenic protein within the...

Ngày tải lên: 11/08/2014, 08:20

... we are in examining the types of errors occurring, the more clear it is we are often lumping together different problems in ways that are neither intellectually nor clinically satisfying. The definitions ... They explore the role of the CPOE system in preventing and perhaps facilitating errors. Their findings are complex. When they combined intercepted and non-intercepted medication err...

Ngày tải lên: 25/10/2012, 10:39