báo cáo khoa học: "Cellular transfer and AFM imaging of cancer cells using Bioimprint" pdf

... studying biological cells using a Bioimprint™ technique with AFM analysis, to enable the high-resolution replication and imaging of the surface topography of human endometrial cancer cells. As non-malignant ... reflects the profile of the imaging tip rather than of the rupture. Further illustrating the range and variation of cell mor- phologies, and the potential...

Ngày tải lên: 11/08/2014, 00:22

... Environmental and heritable factors in the causation of cancer - analyses of cohorts of twins from Sweden, Denmark, and Finland. N Engl J Med 2000, 343:78-85. 3. Leiter U, Garbe C: Epidemiology of melanoma ... is true for the major human cancers, including prostate cancer, breast cancer and colorectal cancer, for which the heritability accounts for 42%, 27% and 35%...

Ngày tải lên: 11/08/2014, 12:20

... the boundaries of most human genes, including transcription start and termination sites and the splicing patterns of internal exons, are rather fuzzy [2-6]. In addition, many of the identified ... of California Santa Cruz (UCSC) Genome Browser, the Vega Genome Browser and an integrated database of human genes and trans- cripts (H-Invitational Database): one finds an averag...

Ngày tải lên: 09/08/2014, 20:22

Ngày tải lên: 12/08/2014, 19:22

... dis- tribution of the energy between the overall tumbling and the internal mobility, and is indicative of the degree of internal restraint of each 15 N– 1 H vector motion. In Fig. 4, most of the points ... minima of J(0) and J(x N ) and a significant maximum of J(0.87x H ), and that emerges not only within helix III, but also over a large portion of the protein, from...

Ngày tải lên: 18/02/2014, 16:20

... Pro, Val or Lys, c-carboxylation of Glu, glycosylation of Ser or Thr, bromination of Trp, sulfation of Tyr, cyclization of N-terminal Gln, and epimerization of several different residues. It ... structure of conomarphin was similar to those of other conotoxin cDNAs. The cDNA-encoded precursor of conomarphin consisted of a conserved M-superfamily signal peptide of 25 re...

Ngày tải lên: 18/02/2014, 17:20

... Araujo Soares RM (2006) Secretion of serine peptidase by a clinical strain of Candida albicans: influence of growth conditions and cleavage of human serum proteins and extracellular matrix components. ... effect of a 5 lm concentration of trappin-2 towards C. albicans was time-dependent, reaching 92% after 6 h and 98% after 18 h (Fig. 5). Effect of NaCl and heparin on the...

Ngày tải lên: 18/02/2014, 17:20

... step increase of 0.2 nm, and a bandwidth of 1 nm. Thermal stability of Rep245 was measured by incu- bating the protein at 60, 70 and 80 °C for 30 min and then recording the CD spectra of the incubated ... plausibly involved in DNA recognition and binding and is positioned left of the active site [14]. Rep245 is both capable of de novo synthesis of DNA primers and of...

Ngày tải lên: 18/02/2014, 18:20

... electrophoresis of the PCR product indicated the presence of two distinct bands between 1000 and 1100 bp of roughly the same extent (not shown). Clo- ning and nucleotide sequencing of these two ... the presence of increasing molar amounts of the other iso- form (1 : 1, 1 : 1000 and 1 : 10 000). Detection of ACMSD I was not influenced by the presence of up to 10 000-fold m...

Ngày tải lên: 19/02/2014, 02:20

... s )1 and K m of 0.182 mm toward NADP, k cat of 5.2 s )1 and K m of 2.9 mm toward NAD. The optimum pH of the enzyme activity is between 8.0 and 9.0, and the optimum temperature is around 60 °C. Using ... catalytic proper- ties of HpSDH and the effects of pH and temperature on HpSDH. The results show that HpSDH has a k cat of 7.7 ± 0.9 s )1 , K m of 0.148 ± 0.028 m...

Ngày tải lên: 19/02/2014, 05:20