báo cáo khoa học: "Analysis of the expression pattern of the BCL11B gene and its relatives in patients with T-cell acute lymphoblastic leukemia" doc

... between the BCL11B gene and the other four genes of interest in the healthy controls. Discussion Increasing numbers of translocations involving the BCL11B locus [8,10,11] or high levels of BCL11B ... 3:44 http://www.jhoonline.org/content/3/1/44 Page 2 of 7 RESEARC H Open Access Analysis of the expression pattern of the BCL11B gene and its relat...

Ngày tải lên: 10/08/2014, 22:21

... occurs in Taiwanese man, and the incidence of oral cavity cancer and eso- phageal cancer is increasing 13.1% and 4.1% respectively in ten years in Taiwan[32]. On the other hand, most of our patients ... many patie nts in the former group. On the other hand, a meta-analysis [13] of six trials comparing induction chemotherapy and radiotherapy with alternating o...

Ngày tải lên: 09/08/2014, 09:20

... [2]. The term LRM was first used by Jackson and Jackson in 1942 to designate stri- dor caused by the indrawing of the supraglottis with inward curling of both sides of the epiglottis, or by the backward ... distress, and death [2]. Many of them are attributed to the exces- sive removal of laryngeal tissue [2]. In cases of LRM and OSAS where the main etiol...

Ngày tải lên: 11/08/2014, 20:20

... after the first line of chemotherapy in patients with positive tumour hormone receptor status. The patients with early disease progression during first-line chemotherapy were not included. In ... (single versus multiple); type of first-line chemotherapy (anthracycline- and/ or taxane-containing regimen versus other); previous line of hormonotherapy administered in...

Ngày tải lên: 08/08/2014, 17:20

... eggs in the one-cell stage to visualize the localization and to mea- sure the mobility of the components in the PGCs. The medaka embryo was peeled off the chorion, and the segment containing the ... diagram of the constructs microinjected into the medaka eggs and transfected into HeLa cells. The olvas, nanos and tudor coding sequences were joined to th...

Ngày tải lên: 18/02/2014, 16:20

... Note the presence of the granules in the cyto- plasm of the cells. Bar, 20 lm. (D) The percentage of EGFP-containing cells displaying granules is shown. The average percentages, including standard ... [8]. In human and HD transgenic mice, the disease corre- lates with the appearance of intraneuronal, intranu- clear and perinuclear aggregates ⁄ inclusions cont...

Ngày tải lên: 19/02/2014, 06:20

... compared with those with the C-terminal domain deleted is consistent with this (Figs 4 and 5). Hybrid proteins carrying the N-terminus of one protein and the Sm domain of the other localize according ... the latter, indicating that in the absence of an N-terminal domain distinct localization is lacking. Finally, the Lsm1p Sm domain by itself (LsmDN1DCp) accumu-...

Ngày tải lên: 07/03/2014, 02:20

... dashes. The active site (YTVAK) and the cofactor-binding motifs are marked in bold. The D43, T67 and A69 residues, involved in cofactor specificity, are indicated by asterisks. Flanking the N-terminal ... at the N-terminus with the hemagglutinin (HA) epitope were produced in COS-7 cells and purified in the microsom- al fraction. The enzymatic activity of this f...

Ngày tải lên: 07/03/2014, 09:20

... bc-crystallin fold. The residues shown in grey indicate the side chains and backbone sites that are involved in calcium binding [24]. The residues in the conserved tyrosine corners are in bold [24]. ... could be the result of loss of induction at the transcriptional level, of loss of activation of the synthetase protein itself, or of derepression of enzym...

Ngày tải lên: 07/03/2014, 12:20

... itself with one of the nodes in the set V C it does so with the one having the highest degree (=3) rather than with others in order to achieve preferential attachment which is the working principle ... as synthe- sis of the distribution of the consonants across the languages. In the current work, with the help of PlaNet we provide a systematic study...

Ngày tải lên: 08/03/2014, 02:21