báo cáo khoa học: "Autonomous growth potential of leukemia blast cells is associated with poor prognosis in human acute leukemias" ppt

... the subcutaneous growth of primary human acute leukemia blast cells and cells from the myeloid blast crisis of chronic myelogenous leukemia [16,17]. The subcutane- ous engraftment and growth of human leukemias ... growth potential of leukemia blast cells is associated with poor prognosis in human acute leukemias Ying Yan* 1,2 , Eric A Wi...

Ngày tải lên: 10/08/2014, 22:20

... induced arthritis and anti- glucose-6-phosphate isomerase (GPI) antibody induced arthritis [2,3], suggesting that FcγRIII is indispensible in autoantibody dependent arthritis. In humans FcγRs are encoded ... respectively). Our findings provide a molecular model of the genetic regulation of autoantibody-induced arthritis by allele-specific affinity of the FcγRs. Introduction Rheuma...

Ngày tải lên: 09/08/2014, 07:20

... (num- bering in red) of the 11 residues surrounding ATB107 within 5 A ˚ in mIGPS (A) were also included in the 14 residues surrounding sub- strate within 5 A ˚ (B). (C) Binding regions of substrate ... the inhibition mechanism of ATB107. To investigate the role of these residues in the inhib- itory effect of ATB107, we compared the binding sites of CdRP and of ATB107. Th...

Ngày tải lên: 07/03/2014, 03:20

... could distinguish hematopoietic stem cells from leukemia- initiating cells [54-57]. Collectively, a combination of cell surface mark- ers is need for the definition of colon cancer stem cells [58-60]. ... percentage of CD133 + tumor cells and the prognosis of colorectal cancer patients. This study showed that the percentage of CD133 + tumor cells was associated w...

Ngày tải lên: 18/06/2014, 15:20

... 2 of 10 invasion of ovarian tumor s [27]. Activation of this path- way has been associated with cisplatin resistance in ovarian cancer [28]. In addition, the inhibition of Akt prevents the growth ... J, Eisenhauer E: Comparison of CA-125 and standard definitions of progression of ovarian cancer in the intergroup trial of cisplatin and paclitaxel versus cisplatin an...

Ngày tải lên: 20/06/2014, 07:20

... glycoprotein serine protease plasminogen activator inhibitor-1 (PAI-1) is a key element in the inhibition of fibrinolysis. The primary role of PAI-1 in vivo is fast act- ing inhibition of tissue- ... 0.095). Multivariate analysis of factors associated with endpoints By multivariate logistic regression analysis, three factors were independently associated with MODS and...

Ngày tải lên: 13/08/2014, 20:22

... Linguistics Exploring the Potential of Intractable Parsers Mark Hopkins Dept. of Computational Linguistics Saarland University Saarbr¨ucken, Germany mhopkins@coli.uni-sb.de Jonas Kuhn Dept. of ... cost of our best solution, we can dis- card this node and discontinue exploration of that subtree. This technique can result in a significant aggregrate savings of computation time, d...

Ngày tải lên: 31/03/2014, 01:20

... coast in the interior of mainland B.C. This contrasts with the other collection sites, which were all within 100 km of the coast and not above 250 m a. s. l. The re- gion of Kootenay Lake is characterized ... made in the spring of 1992 and 1993 of the following dimensions: plant height (h), maximum plant width on both the north-south (x), and the east-west axis (y). Missing...

Ngày tải lên: 08/08/2014, 14:20

... each plot consisting of 81 trees. Height was mea- sured to an accuracy of 0.5 cm by means of a measuring rod and diameter was determined on each stem with a vernier ... rotation ac- cording to Zsuffa (1979). Superior hybrid growth was indicated as a factor respon- sible for the good performance of hybrid poplar in comparison with mer...

Ngày tải lên: 09/08/2014, 02:21

... used to distinguish tumor from normal samples, identification of tissue of origin for tumors of unknown origin or in poorly differentiated tumors and to distinguish different subtypes of tumors. Sample ... cancer-related biomarkers. This is due to the finding that microRNAs display altered expression profiles in cancers versus normal tissue. In addition, microRNAs have been a...

Ngày tải lên: 10/08/2014, 22:21