báo cáo khoa học: "The occurrence and management of fluid retention associated with TKI therapy in CML, with a focus on dasatinib" pptx

... Hematology & Oncology Open Access Review The occurrence and management of fluid retention associated with TKI therapy in CML, with a focus on dasatinib David Masiello, Gerry Gorospe III and Allen ... effu- sions during dasatinib therapy. Dasatinib Dasatinib is a thiazole carboximide with potent activity against BCR-ABL and also SFKs [15]. This age...

Ngày tải lên: 10/08/2014, 22:20

... comparable to that of dacarbazine in a randomized control trial. It offers two potential advantages as it readily crosses the intact blood-brain barrier and can be used as an oral agent. It was also ... survival advantage and safety profile of the management approaches employed in patien ts with primary colonic melanoma. Based on a synthesis of the current data, it app...

Ngày tải lên: 09/08/2014, 01:24

... treatment that included MRI and audiograms. Follow-up included clinical neurological evaluation and MRI brain that were done regularly a t 6 monthly inter- vals in the first year and yearly afterward. Radiosurgery ... sensorineural deterioration in hearing, facial paresis, XII cranial nerve paresis and trigeminal impair- ment were also recorded. Pulstile tinnitus was recorded i...

Ngày tải lên: 09/08/2014, 03:22

... experiments indicated that the latter band was not visible in every electrophoresis analysis of a same 32 P-labeled RNA preparation. Small variations in denaturation–renatur- ation conditions or during ... major causative agent of non -A, non-B hepatitis [1]. This virus has a posit- ive-stranded RNA genome and belongs to the Flavivir- idae family. The RNA contains a large open...

Ngày tải lên: 20/02/2014, 01:20

... charac- terization of the NrfH subunit. The four NrfH hemes are all in a low-spin state (S ¼ 1/2). One of them has a g max at 3.55, characteristic of bis-histidinyl iron ligands in a noncoplanar arrangement, ... chromatogram displayed import- ant alterations (Fig. 3B), yielding two main peaks of approximately 850 and 162 kDa. The SDS/PAGE exami- nation of the eluted frac...

Ngày tải lên: 21/02/2014, 00:20

... %e so+lYe a oct+sAn aununS, with a oor~aAn smotmt oF nalIAenoln, and ~he more oaIAent a preoeaa As, 5he lar|er %5e %npae5 on oSher presences (and therefore on the overall prooeaoLng). There ... ~Ant about 5h ~a ~rt~e~ar example %8 5hat ~t %e embedded wlthAn an "el~mlnatAon of alternat£voo" arll~Nnt etruoture. The5 %a, 5hAm "prqitAo arluaent" 18...

Ngày tải lên: 21/02/2014, 20:20

... Beranek and Newman, Cambridge, Mass., 1972. 24. Ginsparg, J. A robust portable natural language data base interface. Cmlf. on Ap'1)lied Nc~t~ral L~znguage Processing, Santa Munica, Ca., ... grammatical formalism for transportable natural language processing, llm~r. J. Cow~p~t~zt~na~ L~n~ist~cs, to appear. Biermann, A. and Ballard, B. Toward natural language computa...

Ngày tải lên: 17/03/2014, 19:21

... CP133 5¢-TTAAAACTGTGACGATGGT GGA-3¢ with the TAA termination anticodon shown in bold. Amplification reactions were performed in a final vol- ume of 50 lL containing 5 ng of template DNA according to ... RTAE177D was eluted with a linear gradient of 100–300 mm NaCl in the same buffer. Fractions contain- ing RTAE177D were pooled and stored at 4 °C at a con- centration of...

Ngày tải lên: 23/03/2014, 07:20

... unfolding and aggregation by facilitating refolding or degradation, respectively. An increased population of misfolded proteins as a result of genetic or extracellular factors may lead to a saturation ... larger particles that initiate the amyloid cascade. Especially in age-related amyloidosis, this may lead to the accumulation of large quantities of partially folded proteins...

Ngày tải lên: 23/03/2014, 11:20

... each comprising a condi- tion of the stack and the input string. The final state in the parse is an empty input string and a stack containing only the root symbol, SNT. In an unambiguous analy- ... expressive approach, its many vari- ations have found much use in application to natural lan- guage applications and there is a broad literature on Aug- mented Phrase St...

Ngày tải lên: 31/03/2014, 06:20