báo cáo khoa học: "ABT-869, a promising multi-targeted tyrosine kinase inhibitor: from bench to bedside" doc

báo cáo khoa học: "ABT-869, a promising multi-targeted tyrosine kinase inhibitor: from bench to bedside" doc

báo cáo khoa học: "ABT-869, a promising multi-targeted tyrosine kinase inhibitor: from bench to bedside" doc

... development and commercialization for ABT- 869. Phase II clinical trials evaluating ABT-869 for advanced or metastatic hepatocellular carcinoma, meta- static breast cancer, metastatic colorectal cancer, ... growth factor in human hepatocellular carcinoma. Hepatology 1998, 28:68-77. 35. Baldo P, Cecco S, Giacomin E, Lazzarini R, Ros B, Marastoni S: mTOR pathway and mTOR inhibitors as agents fo...
Ngày tải lên : 10/08/2014, 22:20
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Báo cáo khoa học: " The c-Met receptor tyrosine kinase inhibitor MP470 radiosensitizes glioblastoma cells" ppt

Báo cáo khoa học: " The c-Met receptor tyrosine kinase inhibitor MP470 radiosensitizes glioblastoma cells" ppt

... damage-induced apoptosis but also enhanced the rate of repair of DNA strand breaks [5]. HGF also functions as an autocrine or paracrine growth factor and activates a program of cell dissociation and motility coupled ... paraformaldehyde and incubated with the primary antibody against γ-H2AX. The primary antibody was then washed off, and a secondary antibody conjugated to fluorescein iso...
Ngày tải lên : 09/08/2014, 10:20
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Tài liệu Báo cáo khoa học: "DiMLex: A lexicon of discourse markers for text generation and understanding" docx

Tài liệu Báo cáo khoa học: "DiMLex: A lexicon of discourse markers for text generation and understanding" docx

... summary of the situation. Their 'test for relational phrases' is a good start, but geared towards the English language (we are investigat- ing German as well), and furthermore it catches ... individual markers, which are far too numerous to list. We are drawing upon all these sources, trying to place them in a single unified framework. The overall goal can be character...
Ngày tải lên : 20/02/2014, 18:20
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Báo cáo khoa học: Macrocypins, a family of cysteine protease inhibitors from the basidiomycete Macrolepiota procera pot

Báo cáo khoa học: Macrocypins, a family of cysteine protease inhibitors from the basidiomycete Macrolepiota procera pot

... proteases papain, cathepsin L and cathepsin V using benzyloxycar- bonyl (Z)-Phe-Arg-7-amido-4-methylcoumarin (AMC) as substrate, and for legumain with Z-Ala-Ala-Asn-AMC as the substrate, while stopped ... HCl, and pooled and concentrated by ultrafiltration (Amicon UM-3). N-terminal sequence analysis Automated amino acid sequencing of purified natural and recombinant macrocypins was performed as...
Ngày tải lên : 16/03/2014, 02:20
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Báo cáo khoa học: "On2L - A Framework for Incremental Ontology Learning in Spoken Dialog Systems" doc

Báo cáo khoa học: "On2L - A Framework for Incremental Ontology Learning in Spoken Dialog Systems" doc

... Roberto Navigli, and Paola Velardi. 2002. Integrated approach to web ontology learning and engineering. In IEEE Computer - November. Ian Niles and Adam Pease. 2001. Towards a standard upper ontology. ... Loos, and Rainer Malaka. 2006. Towards a separation of prag- matic knowledge and contextual information. In Proceedings of ECAI-06 Workshop on Contexts and Ontologies, Lago di Garda, It...
Ngày tải lên : 23/03/2014, 18:20
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Báo cáo khoa học: "MIMUS: A Multimodal and Multilingual Dialogue System for the Home Domain" doc

Báo cáo khoa học: "MIMUS: A Multimodal and Multilingual Dialogue System for the Home Domain" doc

... an impression, making the system more appealing to use and ap- proachable. References Adam Cheyer and David Martin. 2001. The open agent architecture. Journal of Autonomous Agents and Multi–Agent ... Unification–based Multimodal Parsing Coling–ACL 624–630. Staffan Larsson and David Traum. 2000. Information State and dialogue management in the TRINDI Dia- logue Move Engine Toolkit. Natural La...
Ngày tải lên : 23/03/2014, 18:20
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Báo cáo khoa học: Reaction of human UMP-CMP kinase with natural and analog substrates docx

Báo cáo khoa học: Reaction of human UMP-CMP kinase with natural and analog substrates docx

... UMP-CMP kinase; antiviral analog; 3TC; AraC; phosphorylation. Nucleoside analogs constitute a familly of important antiviral and anticancer drugs. Analogs of thymidine like AZT (2¢3¢-deoxy-3¢azido ... Proc. Natl. Acad. Sci. USA 74, 5463–5467. 19. Munier, H., Gilles, A. M., Glaser, P., Krin, E., Danchin, A. , Sarfati, R. & Barzu, O. (1991) Isolation and characterization of catalytic a...
Ngày tải lên : 08/03/2014, 02:20
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Báo cáo khoa học: "Multilingual Computational Semantic Lexicons in Action: The WYSINNWYG Approach to NLP" docx

Báo cáo khoa học: "Multilingual Computational Semantic Lexicons in Action: The WYSINNWYG Approach to NLP" docx

... lexical processor to specialise or generalise the meaning of a lexeme, for a particu- lar task and on a needed basis. Formally, generalisa- tion and specialisation can be done in various ways, ... analysis and choices in generation. Within Machine Translation (MT), this approach has led researchers to "add" ambiguity in a lan- guage which did not have it from a...
Ngày tải lên : 08/03/2014, 06:20
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Báo cáo khoa học: Cytotoxic activity of nucleoside diphosphate kinase secreted from Mycobacterium tuberculosis pptx

Báo cáo khoa học: Cytotoxic activity of nucleoside diphosphate kinase secreted from Mycobacterium tuberculosis pptx

... supernatant was also analysed for the presence of a cytoplasmic protein, adenylate kinase. Western blot analysis showed that adenylate kinase of M. tuberculosis was absent from the culture supernatant suggesting ... Misra, N., Kostal, J., Kamath, S., Kapatral, V., El-Idrissi, M.E., Prabhakar, B.S. & Chakrabarty, A. M. (1999) A) P2Z-independent and P2Z receptor-mediated macrophag...
Ngày tải lên : 08/03/2014, 08:20
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Báo cáo khoa học: Characterization of the cofactor-independent phosphoglycerate mutase from Leishmania mexicana mexicana docx

Báo cáo khoa học: Characterization of the cofactor-independent phosphoglycerate mutase from Leishmania mexicana mexicana docx

... coupled to NADH oxidation by lactate dehydrogenase (LDH) via enolase (ENO) and pyruvate kinase (PYK), and following the concomitant decrease of absorbance at 340 nm. The assay was per- formed at 25 ... (rabbit muscle PYK and GAPDH and yeast PGK) and Sigma (rabbit muscle ENO and bovine heart LDH). Measuring PGAM activity in a Leishmania lysate The mutase activity was measured in 50 lLoft...
Ngày tải lên : 16/03/2014, 16:20
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