Báo cáo y học: "High nuclear expression of STAT3 is associated with unfavorable prognosis in diffuse large B-cell lymphoma" doc

... level in DLBCL (A) negative nuclear staining of STAT3, (B) negative nuclear staining of P -STAT3, (C) weak nuclear staining of STAT3, (D) weak nuclear staining of P -STAT3, (E) strong nuclear staining of ... ZL et al.: High nuclear expression of STAT3 is associated with unfavorable prognosis in diffuse large B-cell lymphoma. Journal of Hemat...

Ngày tải lên: 10/08/2014, 21:23

... stromelysin-1. Figure 3 Induction of matrix metalloproteinases by relaxin but not by estrogen is accompanied by loss of glycosaminoglycans (GAGs)Induction of matrix metalloproteinases by relaxin ... joint fibrocartilaginous tissues or its induction of MMPs has not been linked to the loss of matrix macromolecules in any tissue. In this study we determined the effects of relax...

Ngày tải lên: 09/08/2014, 06:22

... community-based recruit- ment of asymptomatic women, the relatively large number of study participants, and measurement of CRP by a highly sen- sitive assay. A potential limitation of this study is ... This should be further assessed by a longitudinal study. Introduction Osteoarthritis (OA) is a major cause of morbidity, affecting 60% of men and 70% of women over the age...

Ngày tải lên: 09/08/2014, 10:23

... to refine the associated haplotype. In the same way, the chromosome 2 linkage suggestion observed in the genome scan of our laboratory could not be totally explained by the findings of the ITGAV linkage; ... clinically indicated. Instead, the clinical relevance of the finding is likely to come through better understanding of the RA pathophysiology and may lead to new therapeut...

Ngày tải lên: 09/08/2014, 10:20

... regulators of cell apoptosis, it is possible that HBV infection might alter the cIAPs gene expressing of liver cell, finally instigating the carcinogenesis of the cells it infected. This is agreement ... b b i i o o g g r r a a p p h h y y Xuanyong Lu, PhD is an Assistant Professor of Drexel Institute for Biotechnology and Virology Research, School of Medicine, Drexe...

Ngày tải lên: 02/11/2012, 11:17

... perivasculary and always in the synovial lining and sub-lining layers of the synovium. FcγRII and III positive cells were also observed within lymphocyte infiltrates. The IgG1 iso- type control antibody ... to clearly distinguish between FcγRIIa and IIb, as was demon- strated in our stainings of cell lines (Figure 1b). The staining of healthy synovia (Figure 3a) revealed a novel fin...

Ngày tải lên: 09/08/2014, 10:20

... recently been shown to act synergisti- cally as risk factors, but only in anti-CCP antibody-positive patients with RA [17]. Considering our findings of a stronger predictive value of the combination ... that a missense single nucleotide polymorphism resulting in a substitution of T for C at position 1858 in the protein tyrosine phosphatase nonreceptor type 22 (PTPN22) gene is...

Ngày tải lên: 09/08/2014, 10:20

... lanes correspond to individual patients within Table 1. Staining of the indicated proteins on parallel blots is shown. Equal loading of tissue extracts was controlled by β-actin protein staining. MW indicates ... development of clinical signs of rheumatoid synovial inflammation is associated with increased synthesis of the chemokine CXCL8 (interleukin-8). Arthritis Res 2001,...

Ngày tải lên: 09/08/2014, 01:23

... regulatory mechanisms of the D14-SR gene expression and its possible role in the metabolism of meiosis activating sterols. Mutation analysis of TM7SF2 will clarify whether a defect in this gene underlies ... localization of the enzymes involved in cholesterol biosynthesis and with the puri®cation of the bovine protein from the ER. Determination of D14-SR activity. To dem...

Ngày tải lên: 08/03/2014, 16:20

... the physiological role of these proteins in D. purpurea. Work is underway to determine the precise role of DpARs in plant steroid metabolism in general and in cardenolide biosynthesis in particular. ... by a family of at most five genes. A characteristic function of the ARs is the catalysis of the first reaction in the polyol pathway, the reduction of glucose to sorb...

Ngày tải lên: 18/03/2014, 01:20