Stem Cells in Endocrinology - part 7 ppt

... regenerating pancreatic cells into hepatocyte-like cells. Proc Natl Acad Sci USA 1981 ;78 :2 577 –2581. 97. Hoover KL, Poirier LA. Hepatocyte-like cells within the pancreas of rats fed methyl-defi- cient ... islet-derived progenitor cells into insulin- producing cells. Endocrinology 2002;143:3152–3161. 54. Delacour A, Nepote V, Trumpp A, Herrera PL. Nestin expression in pancreati...

Ngày tải lên: 10/08/2014, 18:21

... production of robust glucose-responsive insulin- secreting cells. Aside from the question of whether ES cell-derived nestin-positive cells can differentiate into insulin-secreting cells, there has been ... population of nestin-expressing cells from mouse ES STEM CELLS IN ENDOCRINOLOGY Edited by LINDA B. LESTER, MS, MD Division of Endocrinology, Diabetes and Clinical Nutrition...

Ngày tải lên: 10/08/2014, 18:21

... CD69, CD71, CD79, CD83, CD90, CD95, CD105, CD1 17, CD123, CD135, CD166, Glycophorin-A, MHC-I, human leukocyte antigen (HLA)-DRII, FMC -7 , Annexin-V, or LIN cell-surface markers. Other investiga- tors ... layers in vitro. This character- istic sets them apart from germ layer lineage stem cells and progenitor cells. Pluripotent stem cells are responsive to any lineage-induction ag...

Ngày tải lên: 10/08/2014, 18:21

... 1.0 staining. In the latter procedure, negative staining controls were digested with chondroitinase-ABC or chondroitinase-AC prior to staining (6 ,7, 86, 87) . Chapter 5 / Murine Embryonic Stem Cells ... somatostatin. Induced pluripotent epiblastic-like stem cells showed minimal intracellular stain- ing for any of the antibodies used (Fig. 2A–C). Induced germ layer lineage endoderma...

Ngày tải lên: 10/08/2014, 18:21

... insulin-expressing cells gradu- ally increased. To characterize the insulin-producing cells further, they mea- sured insulin secretion from 2 0- to 22-day-old EBs and 2 2- and 31-day-old, high-density ... of ES cells into insulin-secreting cells have been developed (23–25). To date, the efficiency of generating insulin-secreting cells using these protocols has been low, and th...

Ngày tải lên: 10/08/2014, 18:21

... Concordance for type 1 (insulin-dependent) and type 2 (non-insulin-dependent) diabetes mellitus in a population-based cohort of twins in Finland Diabetologia 1993;35:1060–10 67. 40. Kumar D, Gemayel ... diabetes is characterized by insulin deficiency secondary to progres- sive T-cell-mediated destruction of insulin-producing pancreatic β cells within the islets of Langerhans. Clinical...

Ngày tải lên: 10/08/2014, 18:21

... stem cells adult, 12, 16, 24 2 47 Stage-specific embryonic antigen (SSEA), 74 SSEA-1, 8 70 , 74 , 77 , 245 SSEA-3, 8, 70 , 74 , 77 , 245 SSEA-4, 8, 70 , 74 , 77 , 99, 245 Steel factor, 27, 33 c-kit, 27, ... germ cells, see EG cells, 25– 27, 49–50, 52–54, 57, 94–95, 2 07 208 Progenitor cells, 10–11, 14– 17, 55, 67, 70 71 , 73 75 , 77 79 , 81, 83–84, 86, 103, 115–1 17, 14...

Ngày tải lên: 10/08/2014, 18:21

... Bloomberg, call a sales representative at: London: +4 4-2 0 -7 33 0 -7 500 New York: + 1-2 1 2-3 1 8-2 000 Tokyo: +8 1-3 -3 20 1-8 900 for in- depth market information and news, visit the Bloomberg website at ... 12–13, 100 income, from REITs, 2 37 income statement, example of, 332–334 individual investors, future role of, 294–2 97 industrial properties, 75 77 Industria...

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... low-level programming languages, graphical model-based programming has been used increasingly for real-time simulation and hardware -in- the-loop (HIL) applications to obtain rapid prototyping ... 38.0 -8 .6 / 6.3 r4(cm) / 4  (deg) 4 / 0 0 / 0 - / - r5(cm) / 5  (deg) 12.5 / 42.0 11.6 / 36.6 -7 .5 / -1 3 r6(cm) / 6  (deg) 15.4 / 0 15.4 /0 - / -  (deg) 51.2...

Ngày tải lên: 19/06/2014, 12:20