Wound Healing and Ulcers of the Skin - part 7 ppsx
Chapter 083. Cancer of the Skin (Part 2) ppsx
... reddish brown, and often whitish pink, and the border of lesion is at least in part aDuring much of this time, the precursor stage, lentigo maligna, is confined to the epidermis. Source: ... Lentigo maligna melanoma Sun-exposed surfaces, 70 5–20a or longer In flat portions, shades of brown and tan particularly malar region of cheek and temple predominant, but whitish ... confined to chronically sun-damaged, sun-exposed sites (face, neck, back of hands) in older individuals. Acral lentiginous melanoma occurs on the palms, soles, nail beds, and mucous membranes. While...
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Chapter 083. Cancer of the Skin (Part 5) ppsx
... origin of primary melanoma and because of the large and varied surface of the nevus. Prophylactic excision early in life can be accomplished by staged removal with coverage by split-thickness skin ... papillomatous surface. The border is sharp, and lesions may be oriented along lines of skin cleavage. Follicular hyper- and hypopigmentation may coexist in a salt -and- pepper ... consideration, then biopsy is appropriate. Some benign look-alikes may be removed in the process of trying to detect authentic melanoma. Table 8 3-5 summarizes the distinguishing features of benign...
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Chapter 083. Cancer of the Skin (Part 7) doc
... on the lower lip. Sun-exposed skin such as the head, neck, hands, and arms are other typical sites of involvement. C. Actinic keratoses consists of hyperkeratotic erythematous papules and ... sun-exposed skin. They arise in middle-aged to older adults and have some potential for malignant transformation. D. Metastatic carcinoma to the skin is characterized by inflammatory, often ... ulceration and a pearly, rolled, telangiectatic tumor border. Chapter 083. Cancer of the Skin (Part 7) Treatment of Metastatic Disease Melanoma can metastasize to any internal organ, the brain...
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Chapter 083. Cancer of the Skin (Part 1) ppt
... blacks, and East Asians have rates 10–20 times lower than lighter-skinned whites. In keeping with the role of sun exposure, the incidence is inversely correlated with the latitude of residence; ... Cancer of the Skin Melanoma Pigmented lesions are among the most common findings on skin examination. The challenge is to distinguish cutaneous melanomas, which may be lethal, from the remainder, ... in blacks, Asians, and Hispanics and occurs as an enlarging hyperpigmented macule or plaque on the palms and soles. Lateral Chapter 083. Cancer of the Skin (Part 1) Harrison's Internal...
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Chapter 083. Cancer of the Skin (Part 4) pot
... areas; the back is the most common site, but dysplastic nevi may also be seen on the scalp, breasts, and buttocks Generally on the sun-exposed surfaces of the skin above the waist; the scalp, ... lymph nodes and palpation of the abdominal viscera are part of the staging examination for suspected melanoma. The patient should be advised to have other family members screened if either melanoma ... pigment may fade off into surrounding skin; macular portion at the edge of the nevus Round; sharp, clear-cut borders between the nevus and the surrounding skin; may be flat or elevated Size...
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Chapter 083. Cancer of the Skin (Part 6) potx
... cells and minimize possible local recurrence. The appropriate width of the margin is a source of controversy. A World Health Organization trial that prospectively randomized between 1- and 3-cm ... feasible (such as the face, hands, or feet), an incisional biopsy through the most nodular or darkest area of the lesion is acceptable; this should include the vertical growth phase of the primary ... thick) reported that the narrower margin resulted in higher rates of local recurrence but no difference in rates of nodal or distant metastases, Chapter 083. Cancer of the Skin (Part 6) Biopsy...
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Chapter 083. Cancer of the Skin (Part 9) ppt
... behavior of the tumor. These include the size, location, and degree of histologic differentiation of the tumor as well as the age and physical condition of the patient. Surgical excision, MMS, and ... modalities with higher cure rates and lower morbidity. In patients with a history of skin cancer, long-term follow-up for the detection of recurrence, metastasis, and new skin cancers should be emphasized. ... repair DNA and may decrease the rate of NMSC in xeroderma pigmentosum. Squamous Cell Carcinoma The therapy of cutaneous SCC should be based on an analysis of risk factors influencing the biologic...
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Chapter 083. Cancer of the Skin (Part 10) pps
... Jr et al: The histogenesis and biologic behavior of primary human malignant melanoma of the skin. Cancer Res 29 :70 5, 1969 [PMID: 577 3814] Friedman RI et al (eds): Cancer of the Skin. Philadelphia, ... in the 1990s: The continued importance of early detection and the role of physician examination and self-examination of the skin. CA Cancer J Clin 1:201, 1991 Kirkwood JM et al: High-dose ... 9 17 9 47 Lippman SM et al: l3-cis-retinoic acid and interferon-a2a: Effective combination therapy for advanced squamous cell carcinoma of the skin. J Natl Cancer Inst 84:235, 1992 [PMID: 173 4084]...
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Chapter 091. Benign and Malignant Diseases of the Prostate (Part 7) potx
... outside of the area of the prostate bed and is unlikely to be controlled with radiation therapy. disease. The practice evolved from studies of predominantly elderly men with well-differentiated ... evidence of disease on scan. For these patients the central issue is whether the rise in PSA results from persistent disease in the primary site, systemic disease, or both. In theory, disease in the ... radiation therapy. The decision to recommend radiation therapy after prostatectomy is often made on the basis of the pathologic findings at surgery, as imaging studies such as CT and bone scan...
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Monitoring Control and Effects of Air Pollution Part 7 pdf
... mortality in 20 US cities, 198 7- 1 994. The New England Journal of Medicine 343: 174 2-1 74 9. Emission and Formation of Fine Particles from Hardcopy Devices: the Cause of Indoor Air Pollution 123 ... night, there were significant decrease in the particulate numbers and mass concentrations from the working hours of the machine during the day. While during the working hours, the number of particulate ... al., 20 07) in the study that fine particles were not directly generated from toner particles but by the secondary formation of the VOCs and the water mists emitted during the operation of the printers....
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