Mollison’s Blood Transfusion in Clinical Medicine - part 3 pdf

... Chapter 0 03. Decision-Making in Clinical Medicine (Part 2) The following three examples introduce the subject of clinical reasoning:  A 46-year-old man presents to his internist with ... would be inaccurate if the clinical (pretest) picture of the patient being tested indicates a low probability of disease (e.g., a 30 -year-old woman with no risk factors). As illustrated...

Ngày tải lên: 06/07/2014, 08:20

... disease is the underlying cause. The absence of a resting Chapter 0 03. Decision-Making in Clinical Medicine (Part 3) Diagnostic Hypothesis Generation Cognitive scientists studying the thought ... make teaching diagnostic reasoning difficult is that expert clinicians do not follow a fixed pattern in patient examinations. From the outset, they are generating, refining, and d...

Ngày tải lên: 06/07/2014, 08:20

... representing another confounding variable in the pedigree analysis. Some of the aforementioned features of the family history are illustrated in Fig. 6 4-1 . In this example, the proband, a 36 -year-old ... family history of cancer. Chapter 064. The Practice of Genetics in Clinical Medicine (Part 3) Recall of family history is often inaccurate. This is especially so...

Ngày tải lên: 07/07/2014, 01:20

... Prevention of urinary tract infections Kidney transplantation Nephrogenic XL, AR AVPR2, Fluid Chapter 064. The Practice of Genetics in Clinical Medicine (Part 7) Therapeutic Interventions ... Parkinson disease AD SNCA, PARK2 Amantadine, anticholinergics, levodopa, monoamine oxidase B inhibitors Wilson disease AR ATP7B Zinc, trientene Abbreviations: AD, autosoma...

Ngày tải lên: 07/07/2014, 01:20

... transcription factor complex involved in Chapter 065. Gene Therapy in Clinical Medicine (Part 2) Figure 6 5-1 Indications in gene therapy clinical trials. The chart divides clinical gene transfer ... reconstitution of the immune system, including documented responses to standard childhood vaccinations, clearing of infections, and remarkable gains in growth occu...

Ngày tải lên: 07/07/2014, 01:20

... factor (VEGF) inhibitors such as angiostatin, or through the use of RNAi-mediated Chapter 065. Gene Therapy in Clinical Medicine (Part 3) Long-Term Expression in Genetic Disease: In Vivo Gene ... hepatocytes, long-term expression can be achieved even in the absence of integration. Clinical trials using recombinant AAV vectors are now ongoing for muscular dystrophies,...

Ngày tải lên: 07/07/2014, 01:20

... dysfunction after spinal cord injury reflects demyelination, and both ES cells and marrow-derived stem cells are able to facilitate remyelination after experimental spinal cord injury. Clinical trials ... for stem cell therapies include spinal cord injury, amyotrophic lateral sclerosis, stroke, traumatic brain injury, Batten disease, and Parkinson's disease. In Parkinson's...

Ngày tải lên: 07/07/2014, 01:20

... Botulinum toxin in the management of ble- pharospasm. Arch Neurol 1986; 43: 380 38 2. Jankovic J, Ford J. Blepharospasm and orofacial-cervical dystonia: clinical and pharmacological findings in 100 ... heavy chain and a light chain. The for- mer is important in binding to the pr esynaptic neuro- muscular terminals, whereas the latter is released into the terminals. The light chain is...

Ngày tải lên: 09/08/2014, 20:22

... high-affinity interleukin-2 receptor, anti-CD25); alemtuzumab (anti-CD52, Campath 1H); rituximab (anti-CD20); anti-CD40L/-CD154 (IDEC- 131 ); anti-IL-12, anti-CD6; anti-CD3 (OKT3); anti-Vβ5.2/5 .3 + T ... cells; anti-CD4; integrin inhibitors Lymphocyte-specific cytoplasmic protein – tyrosine kinase P56lck; zeta-associated protein (ZAP )-7 0; protein kinase C theta; mitogen-activated protein...

Ngày tải lên: 10/08/2014, 00:20