Blood Disorders in the Elderly - part 1 pps

... 6.8% 32.8% 36.4% 1. 2% 2.6% 19 .1% 11 .6% 25.4% 1. 9% 0.9% 24.4% 5.5% 22.3% 7.4% 0% 5% 10 % 15 % 20% 25% 30% 35% 40% 10 10 .0 10 .9 11 .0 11 .9 12 .0 12 .9 13 .0 13 .9 14 .0 14 .9 15 .0 15 .9 16 .0ϩ Men Women Hemoglobin [g/dL] Percent of total 0.5% 1. 1% Figure 2.2 Distribution of hemoglobin in persons aged ... painful bone-marrow aspirate exam- ination of normoblasts [33]....

Ngày tải lên: 10/08/2014, 16:22

... as THP-doxorubicin (pira- rubicin) [14 0 14 2], epirubicin [14 3 ,14 4], and idaru- bicin [14 3], have been investigated. Unfortunately, in these studies, the control arm was not CHOP, did not include ... tract in ltra- tion also occur [11 2 ,11 3]. Hepatic involvement is common, occuring more frequently than in other non-Hodgkin lymphomas [11 4]. ATLL results in an immunodefi cie...

Ngày tải lên: 10/08/2014, 16:22

... Pharma- cokinetics of 2-F-ara-A (9-beta-D-arabinofuranosyl- 2- uoroadenine) in cancer patients during the Phase I clinical investigation of fl udarabine phosphate. Semin Oncol 19 90; 17 : 18 –32. 74. ... Dermatol Ther 2003; 16 : 311 – 21. 19 5. Duvic M, Cather JC. Emerging new therapies for cutaneous T-cell lymphoma. Dermatol Clin 2000; 18 : 14 7–56. 19 6. Nichols J, Foss F,...

Ngày tải lên: 10/08/2014, 16:22

... showing unaltered stain- ing profi les of the ckit, Sca -1 , and lineage antigens in old mice [9 ,11 ,18 ]. Systemic versus cellular aging What is aging? When does it begin? What are its tar- gets? These ... machinery. Their phos- phorylation is governed by the concerted actions of the cyclin-dependent kinases (cdks) and the cdk inhibitors (ckis). Chief among the ckis are p16 INK...

Ngày tải lên: 10/08/2014, 16:22

... [10 ,11 , 91] . During the last two dec- ades there has been much progress in understanding the role of the immune system, pro -in ammatory cytokines [13 ], gene interactions [92], point muta- tions, ... A/Singapore/6/86 H1N1 strain, not contained in the vaccine [16 ]. The antibody produced by this group of elderly also neutralized A/Taiwan /1/ 86-induced viral cytotoxic-...

Ngày tải lên: 10/08/2014, 16:22

... IL-6 which in MGUS MM-Low LI IL-6 IL-1b MM-High LI M-protein adhesion molecules lytic bone lesions paracrine IL-6 OAF IL-1b Figure 11 .1 Role of IL -1 and IL-6 in the transition of MGUS to MM. ... concentration, the hyperten- sion/diabetes group had a signifi cantly higher EPO level for the baseline measurement than subjects 5 10 15 20 25 30 35 40 0 5 10 15 20 25 30 10...

Ngày tải lên: 10/08/2014, 16:22

... cyanocobalamin (vitamin B 12 ). Ann Intern Med 19 94; 12 0, 211 15 . 30. Ruscin JM, Page RL 2nd, Valuck RJ. Vitamin B (12 ) defi - ciency associated with histamine(2)-receptor antago- nists and a proton-pump ... Invest 2004; 11 3: 12 51 3. 76. Lee P, Peng H, Gelbart T, Wang L, Beutler E. Regulation of hepcidin transcription by interleukin -1 and inter- leukin-6. Proc Natl Acad Sci...

Ngày tải lên: 10/08/2014, 16:22

... transloca- tions involving the immunoglobulin heavy-chain gene locus located on chromosome 14 q32 [13 ,14 ]. Five recurrent partner translocations have been described, including the following: 11 q13, ... Keller JW. 5-Azacytidine (NSC 10 2 816 ): a new drug for the treatment of myeloblastic leukemia. Blood 19 76; 48: 3 31 7. 11 3. Christman J. 5-Azacytidine and 5-aza-2’-deoxy...

Ngày tải lên: 10/08/2014, 16:22

... 214 18 types 14 17 unexplained 14 , 17 , 95, 19 3, 203–4 incidence 16 2, 16 3 treatment 217 18 anemia of chronic in ammation (ACI) 14 , 15 16 , 17 5–7, 19 4, 205 angina 438, 4 41 angiogenesis 10 6, 14 2 angioimmunoblastic ... Index 477 therapy 19 4–5 transport 17 1, 17 3–4, 208–9 iron-binding proteins 17 1 iron defi ciency epidemiology 17 8 erythropoietin levels 209 1...

Ngày tải lên: 10/08/2014, 16:22

... edition 19 67 Eighth edition 19 87 Reprinted 19 67 Reprinted 19 88 Library of Congress Cataloging -in- Publication Data Klein, Harvey G. Mollison’s blood transfusion in clinical medicine. – 11 th ed. ... 3.0–7.0 15 4 15 4 0 0 0 0 None Oxypolygelatin Intravascular 200 7.4 15 5 10 0 0 0 1 0 None Adapted from Committee on Fluid Resuscitation for Combat Casualties (19 99). © 19 51...

Ngày tải lên: 10/08/2014, 16:23