báo cáo khoa học: " Human Papillomaviruses, 16INK4a and Akt expression in basal cell carcinoma" potx

... β-HPV in neoplastic proliferation, the expression of two host genes, p16INK4a and Akt, were investigated. The expression pattern of p16INK4a in dysplastic squamous and glandular cervical cells in ... carcinoma in situ and invasive squamous cell carcinoma of the skin and links between p16INK4a expression and infiltrative behavior. Mod Pathol 2004, 17:1464–74. 38....

Ngày tải lên: 10/08/2014, 10:21

... dilution, then incubated in secondary biotinylated antibody and finally counterstained with Hematoxylin. Immunohisto- chemical analyses of c-erbB-2 expression describe the intensity and staining pattern ... of themembraneinmorethan10%ofthetumorcells (1+); complete staining of the membrane with weak or moderate intensity in more than 10% of the neoplastic cells (2+); and strong sta...

Ngày tải lên: 10/08/2014, 10:21

... confirming that the two proteins interact with each other. Determination of the effect of MT2 and MT3 in TTR–Ab binding The effect of hTTR–MT2 and hTTR–MT3 interactions in TTR ⁄ Ab binding was characterized ... (CP) of the brain [1], which is known for the transport of thyroid hormones and the indirect transport of retinol [2] via its binding to plasma retinol-binding protein [3]. Wi...

Ngày tải lên: 23/03/2014, 03:20

... strong ligand binding. II. The binding of the pancreatic trypsin inhibitor and of isoleu- cine-valine and of sequentially related peptides to F. Polticelli et al. Modelling haptoglobin structure FEBS ... HPT b-chain, while the HPT a-chain is not involved in Hb binding [31]. In agreement, in our model the b-chain N-terminal residues partially overlap with the 128–137 loop region (Fig...

Ngày tải lên: 23/03/2014, 06:20

... having a subsequence belonging to one file and the remaining sequence in another file were not included in our calculations. All calculations on the human genome utilized both the original and ... statistical properties of short subsequences in microbial identifi- cation. In Proceedings of the International Conference on Mathematics and Engineering Techniques in Medicine and...

Ngày tải lên: 23/03/2014, 11:20

... become another candidate affecting reg- ulation of cell growth and providing new insights in pro- liferation control. In previous investigations of gene expression in mammary gland tissue from ... growth in rat mammary epithelial cells and in breast tumor cells of human origin. Thus, a-amylase may be considered a novel, promising target for balancing cellular growth, which...

Ngày tải lên: 10/08/2014, 10:21

... Modeling of Language Variability. In Proceedings of the PASCAL Workshop of Learning Methods for Text Understanding and Min- ing. M.C. De Marneffe, B. MacCartney, and C.D. Man- ning. 2006. Generating ... achieved in the most challenging setting 4 Using Google Translate. 122 lems. Given two pages (P1 and P2), these issues include identifying, and properly managing: (1) Text portions...

Ngày tải lên: 19/02/2014, 19:20

... the informant in that it informs him what the inquirer is interested in (what is on her/his mind) and * Some other influences on syntactic expression are discussed in [MORGAN and ... context. In the declarative, elements functioning in asserting information What the listener is presumed not to know are called new. In the question, elements funci:ioning...

Ngày tải lên: 21/02/2014, 20:20

... edge b-strands, hampering intermolecular backbone interac- tions, and (b) inward-pointing charged side chains that become trapped in the hydrophobic core of the fibril upon aggregation. Lysines are ... protein. On the other hand, the location of His5 1in the D-strand is intrigu- ing: in native b2m, the His51 side chain points out- wards, although, in the structures of both the P32A mu...

Ngày tải lên: 06/03/2014, 00:20

... proteins bind RNA, but it is presumed to occur in a similar fashion. Putative RNA-binding residues for budding yeast Lsm1p and Lsm8p are indicated by asterisks in Fig. 1A,B, and in red in Fig. ... intersubunit and protein–RNA contacts [29,33,34]. Crystal structures and cross-linking data have shown that RNA-binding residues in Sm(-like) proteins are located in loop 3 (betw...

Ngày tải lên: 07/03/2014, 02:20