báo cáo khoa học: "Uterine and ovarian carcinosarcomas overexpressing Trop-2 are sensitive to hRS7, a humanized anti-Trop-2 antibody" pdf
... Uterine and ovarian carcinosarcomas overexpressing Trop-2 are sensitive to hRS7, a humanized anti -Trop-2 antibody Rhoda Raji 1* , Federica Guzzo 1* , Luisa Carrara 1 , Joyce Varughese 1 , Emiliano ... (stefania.bellone@yale.edu) Marta Betti (martignaz@hotmail.com) Paola Todeschini (paolat09@yahoo.it) Sara Gasparrini (sara.gasparrini@yale.edu) Elena Ratner (elena.r...
Ngày tải lên: 10/08/2014, 10:21
... the Statistical Analysis System (SAS 1996) using repeated-measures ANOVA. Hormonal data were analyzed after normalization by log trans- formation. Endocrine and ovarian changes in response to the ... RIA analysis, and to Dr. A. F. Parlow and Dr. J. Roser for supplying hormone and antibody preparations for the LH and FSH assays. Financial support was given by CIDEC (Facultad d...
Ngày tải lên: 12/08/2014, 15:21
... retained at 5 °C at pH 7.5 and indicate that changes in kinetic parameters were most probably due to tem- perature alone. Sensitivity to adenylates (ATP inhibi- tion, AMP and ADP activation) was ... in hibernation. In Hibernation and Torpor in Mammals and Birds (Lyman CP, Willis JS, Malan A & Wang LCH, eds), pp. 273–282. Academic Press, New York, NY. 19 Malan A (1986) pH a...
Ngày tải lên: 19/02/2014, 16:20
Tài liệu Báo cáo khoa học: Structure and membrane interaction of the internal fusion peptide of avian sarcoma leukosis virus pdf
... resi- dues around Pro13 used to determine the type II b-turn are indicated. Particularly not eworthy are the cross-peaks attributed to bHofAla12 and NH o f Val15, and aH of P ro13 and NH o f Val15. 4732 ... U SA). Before depositing sample, the 45° germanium ATR-plate (2 · 5 · 50 mm) was cleaned by a plasma cleaner (Harrick, Ossining, N Y, USA). Analysis of ATR-FTIR data was pe...
Ngày tải lên: 19/02/2014, 16:20
Báo cáo khoa học: Energetic and metabolic transient response of Saccharomyces cerevisiae to benzoic acid docx
... some yeasts such as Saccharomyces cerevi- siae and Zygosaccharomyces bailii, both of which are known to be important food spoilage yeasts, are able to adapt to the presence of these weak acids ... exported, and this process consumes energy. This leads to an increase in the extracellular total benzoate concentration, a decrease in the intracellular total benzoate concentra- t...
Ngày tải lên: 07/03/2014, 04:20
Báo cáo khoa học: Folding and turnover of human iron regulatory protein 1 depend on its subcellular localization pdf
... stabilization of mitochondrial DNA [4]. In mammalian cells, two aconitase paralogs are pre- sent in the cytosol: iron regulatory proteins 1 and 2 (IRP1 and IRP2). IRP1 and IRP2 are important regu- lators ... similar way, pathophysiological features of human mitochondrial diseases, such as X-linked side- roblastic anaemia with cerebellar ataxia, include accu- mulation of materials in...
Ngày tải lên: 07/03/2014, 10:20
Báo cáo khoa học: Transthyretin and familial amyloidotic polyneuropathy Recent progress in understanding the molecular mechanism of neurodegeneration pdf
... fibrils and large amyloid deposits are less toxic. Amyloid proteins share common features such as the ability to bind to lipid membranes and to activate specific intracellular path- ways, particularly ... P & Saraiva MJ (1997) Screening and biochemical characterization of transthyretin variants in the Portuguese population. Hum Mutat 9, 226–233. 8 Nakazato M, Kangawa K, Minami...
Ngày tải lên: 07/03/2014, 10:20
Báo cáo khoa học: Structural and functional roles for b-strand 7 in the a-crystallin domain of p26, a polydisperse small heat shock protein from Artemia franciscana pdf
... 5¢-CACGTACAAAGAGAACGTCGACGACG-3¢ 5¢-CGTCGTCGACGTTCTCTTTGTACGTG-3¢ R11 4A 5¢-GAGAATTTCGAGCACGATACAGACTCCC-3¢ 5¢-GGGAGTCTGTATCGTGCTCGAAATTCTC-3¢ Y116D 5¢-CGACGACGAGACAGACTCCCAGAACATGTC-3¢ 5¢-GACATGTTCTGGGAGTCTGTCTCGTCGTCG-3¢ Y. Sun et al. ... as sense and antisense, respectively, for each mutation. p26 mutation Primer R110G 5¢-GGACACGTACAAGGAGAATTTCGACGACG-3¢ 5¢-CGTCGTCGAAATTCTCCTTGTACGTGTCC...
Ngày tải lên: 07/03/2014, 12:20
Báo cáo khoa học: Expression and characterization of the protein Rv1399c from Mycobacterium tuberculosis A novel carboxyl esterase structurally related to the HSL family docx
... is composed of 7 parallel b strands associated to an anti- parallel strand (b2) and is surrounded by 5 helices (a1 , a2 , a3 , a7 anda8). T he second domain c onsists of helices a4 , a5 and a6 a ll clustered ... connecting strand b3 to helix a1 and two small h elices (a4 anda6). The catalytic site consists of a functional catalytic triad found in all serine enzymes of the...
Ngày tải lên: 07/03/2014, 16:20
Báo cáo khoa học: "Analysis and Synthesis of the Distribution of Consonants over Languages: A Complex Network Approach" pptx
... Oltvai, and A. L. Barab ´ asi. 2000. The large-scale organization of metabolic networks. Nature, 406:651-654. R. Jakobson and M. Halle. 1956. Fundamentals of Language, The Hague: Mouton and Co. P. ... preferential at- tachment, 3 Mean error is defined as the average difference between the ordinate pairs where the abscissas are equal. • Provide a simplified mathematical model to su...
Ngày tải lên: 08/03/2014, 02:21