báo cáo khoa học: "CpG oligonucleotides suppress HepG2 cells-induced Jurkat cell apoptosis via the Fas-FasL-mediated pathway" ppt

... NOK-2-treated Jurkat c ells, the CpG-ODN-treated HepG2 and untreated Jurkat cells, and the untreated HepG2 and the CpG-ODN-trea- ted Jurkat cells for 24, respectively. Subsequently, the suspended Jurkat cells ... neuroblastoma cells. Oligonucleotides 2004, 14:287-98. doi:10.1186/1756-9966-30-48 Cite this article as: Zheng et al.: CpG oligonucleotides suppress HepG2...

Ngày tải lên: 10/08/2014, 10:21

... with the precursor–receptor complex and the putative translocase is formed. (iii) The precursor protein is then transported in a process energized by the DpH across the thylakoid membranes. The ... from the translocase into the lipid bilayer, where the signal peptide is removed by the TPP and the mature protein is released into the lumen. After protein transport, Tha4...

Ngày tải lên: 07/03/2014, 03:20

... both the AdoMet synthesis and trypolyphos- phatase activities in the presence of the sulfhydryl reagent N-ethylmaleimide. The panels shown in Fig. 4 represent the time-course of AdoMet synthesis ... decay in the presence of the sulfhydryl reagent. The semi-inactivation time of the rapid process was calculated to be 1.6 min, whereas the slope of the slow semi-inactivation...

Ngày tải lên: 08/03/2014, 08:20

... (aquo/hydroxo) group in the oxidized (3,3) state of the cluster, while the other (W1, trans to the pair of coordinated carboxylates) occurs as an unprotonated oxo ion (O 2– ). The glutamate coordinated to the Mn2 ... associated with the oxo bridge, as well as the other ligands binding the cluster. In contrast, the EPR spectrum of the WT LPC (3,3) complex lacks any signifi...

Ngày tải lên: 08/03/2014, 08:20

... deter- mine enzyme specificity or the lack thereof [10,13,20]. Similar to the other members of the NagD family, AraL shares two Asp residues in the cap domain (Fig. 2). To date, the number of characterized ... DaraL. Above is displayed the coding sequence of the 5¢-end of the araL gene. The putative ribosome-binding site, rbs, is underlined. The 5¢-end of the araL gene pr...

Ngày tải lên: 14/03/2014, 23:20

... cancer chemotherapeutic agent. Moreover, the cytotoxicity of RNase T1/PS/HVJ does not appear to be related to the origin of the cell line, as the K-562 human erythroleukemia cell line and the SAS ... that the low transfec- tion efficiency of HVJ envelope vector resulted from weak association o f the vecto r with the cell membrane due to the negative charge on both the...

Ngày tải lên: 23/03/2014, 12:20

... present at either proteolysis intervals. Therefore, the cleavage location is partially dependent on the incubation time of the substrate with the protease, at least within the limits of the experimental ... steps. The system was then heated to 300 K in 2 ps, and a further 118 ps simulation was run in order to let the system equilibrate, and finally the production run could st...

Ngày tải lên: 30/03/2014, 01:20

... analysis, the retention time of the reaction product for PsLADH (13.32 min) was almost the same as that of l-lactate (13.35 min), but not methylglyoxal (12.36 min); therefore, the enzyme catalyses the NAD(P) + -linked ... l-rhamnose in P. stipitis cells, but the PsALDH* gene was not (Fig. 2C). These results strongly suggest the physiological function of PsLADH in the alternati...

Ngày tải lên: 30/03/2014, 02:20

... character to the Pokemon promoter, we speculated whether it might decrease the activity of the SV40 Fig. 6. The NEG-D element is involved in the negative regulation of the Pokemon promoter. (A) The left-hand ... E47 was not mediated via SREs but via the E-boxes. Reducing the distance between the two E-boxes abol- ished synergistic activation. Therefore, the synergist...

Ngày tải lên: 30/03/2014, 04:20

... feature of the steroid cell tumor would be unu- sual for the juvenile granulosa cell tumor, which almost always contains diagnostic areas with follicles. When the lutein cells in a lutinized thecoma ... hormone-producing cells occurs as a secondary event [1,2]. A predominantly diffuse pattern in luteinized granulosa cells might suggest the diagnosis of steroid cell tumor, but t...

Ngày tải lên: 10/08/2014, 23:20