báo cáo khoa học: " Silibinin induces apoptosis via calpain-

báo cáo khoa học: " Silibinin induces apoptosis via calpain-dependent AIF nuclear translocation in U87MG human glioma cell death" potx

... calpain-dependent AIF nuclear translocation in the silibinin- induced glioma cell death. Conclusion The present study demonstrated that silibinin induces apoptosis through AIF nuclear translocation ... Silibinin + CHO AIF ȕ-actin LacZ mi -AIF Silibinin (C) (D) Figure 5 Role of AIF nuclear translocation in silibinin- induced cell death. (A) Cells we...

Ngày tải lên : 10/08/2014, 10:21

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Tài liệu Báo cáo khoa học: Altered expression of CD1d molecules and lipid accumulation in the human hepatoma cell line HepG2 after iron loading pptx

... background staining in unlabeled cells or resting T cells (data not shown). Yet, HepG2 cells grown in iron-rich media showed a further increase in ROS production as deter- mined by an increase in DCFH ... with saponin allowed us to determine that HepG2 cells contained high levels of intracellular ferritin, with some ferritin being expressed at the cell surface and culture in iron-...

Ngày tải lên : 19/02/2014, 16:20

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báo cáo khoa học: " Statin-induced apoptosis via the suppression of ERK1/2 and Akt activation by inhibition of the geranylgeranyl-pyrophosphate biosynthesis in glioblastoma" potx

... elucidate the mechanism by which statins induce apoptosis in C6 glioma cells. Methods: The cytotoxicity of statins toward the C6 glioma cells were evaluated using a cell viability assay. The enzyme activity ... Bim, and cell death in glioblastoma cells. J Neurochem 2004, 89:168-178. 7. Koyuturk M, Ersoz M, Altiok N: Simvastatin induces proliferation inhibition and apoptosis...

Ngày tải lên : 10/08/2014, 10:21

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Tài liệu Báo cáo khoa học: The central role of CDE/CHR promoter elements in the regulation of cell cycle-dependent gene transcription pdf

... in the Cdc25C promoter by in vivo footprinting as being protected in G 0 cells. The Cdc25C gene is not expressed in resting cells or in cells in G 1 phase. Only in G 2 phase can strong transcription ... specifying partic- ular binding sites [20,22,61,90,92–96]. Very recently, it has been shown that Lin-54 can bind to two sites in the Cdc2 promoter in vitro. Lin-54 binds i...

Ngày tải lên : 16/02/2014, 09:20

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Tài liệu Báo cáo khoa học: Direct identiﬁcation of hydrophobins and their processing in Trichoderma using intact-cell MALDI-TOF MS docx

... hfbI – , only the respective mass peak was missing (Fig. 3B). Deviating post-translational processing of hydrophobins in H. jecorina strains To investigate strain diversity with respect to meta- bolite ... amounts) and requiring minimal sample preparation. Bacterial intact -cell MALDI-TOF spectra in the range 2–20 kDa are dominated by a set of ri- bosomal proteins as highly abundant intr...

Ngày tải lên : 19/02/2014, 02:20

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Báo cáo khoa học: Antioxidant defences and homeostasis of reactive oxygen species in different human mitochondrial DNA-depleted cell lines pot

... ﬂux in the studied q 0 cells, and that there are cell line-to -cell line v ariations in intracellular antioxidant defences and ROS homeostasis. In fact among the studied cells, those originating ... up-regulated in lymphoblastoid q 0 cells, as a compen- satory phenomenon in maintaining cell viability [18]. Our results conﬁrm PMRS as a possible source of ROS in bone cells, a s...

Ngày tải lên : 16/03/2014, 18:20

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Báo cáo khoa học: "Factors that predict outcome of intensive care treatment in very elderly patients: a review" potx

... relatives. Competing interests The author(s) declare that they have no competing interests Authors' contributions EdJ acquired and interpreted data, and participated in prepar- ing the manuscript. SEdR interpreted ... patients requiring ventilatory support in intensive care. Aging 1995, 7:221-227. 8. Cohen IL, Lambrinos J: Investigating the impact of age on outcome of mechanical...

Ngày tải lên : 12/08/2014, 22:21

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báo cáo khoa học: " Oxymatrine induces human pancreatic cancer PANC-1 cells apoptosis via regulating expression of Bcl-2 and IAP families, and releasing of cytochrome " pptx

... the further investigation. Oxymatrine inducing PANC-1 cells apoptosis Oxymatin e-induced apoptotic cell death was found using Annexin V-FITC/PI double stained flow cytometry. Annexin V-FITC positive ... Nat Rev Mol Cell Biol 2004, 5:897-907. 18. Chen M, Wang J: Initiator caspases in apoptosis signaling pathways. Apoptosis 2002, 7:313-319. 19. Altieri DC: Survivin and iap proteins...

Ngày tải lên : 10/08/2014, 10:21

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báo cáo khoa học: "Osthole induces G2/M arrest and apoptosis in lung cancer A549 cells by modulating PI3K/Akt pathway" pptx

... Gupta S, Afaq F, Mukhtar H: Involvement of nuclear factor-kappa B, Bax and Bcl-2 in induction of cell cycle arrest and apoptosis by apigenin in human prostate carcinoma cells. Oncogene 2002, 21:3727-38. 32. ... were procured locally. Cell line and culture conditions The human lung cancer cell line A549 was obtained from the China Center for Type Culture Collection (Wuhan, Ch...

Ngày tải lên : 10/08/2014, 10:21

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Tài liệu Báo cáo khoa học: Role of transcription factor activator protein 1 (AP1) in epidermal growth factor-mediated protection against apoptosis induced by a DNA-damaging agent doc

... factor protects human gastric adenocarcinoma MKN74 cells from ADR-induced apoptosis by blocking caspase 9 activity via the PtdIns-3K ⁄ Akt survival signaling pathway [33]. In contrast to these results, in ... protein-tyrosine kinases in vivo and in vitro. Cell 57, 1109–1122. 18 Holgado-Madruga M, Emlet DR, Moscatello DK, Godwin AK & Wong AJ (1996) A Grb2-associated docki...

Ngày tải lên : 19/02/2014, 06:20

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