báo cáo khoa học: "Promising cytotoxic activity profile of fermented wheat germ extract (Avemar®) in human cancer cell lines" pot

... as: Mueller et al.: Promising cytotoxic activity profile of fermented wheat germ extract (Avemar ® ®) in human cancer cell lines. Journal of Experimental & Clinical Cancer Research 2011 30:42. Submit ... IC 50 range varying from 0.3 mg/ ml to 0.54 mg/ml yielding in a RAA of 1.7-3.3 (Figure 1). Detection of the mode of cell death induced by FWGE in a...

Ngày tải lên: 10/08/2014, 10:21

... ubiquitinated in H1.2, H1.3 and H1.4 in human HeLa cells, but not in MCF7 cells. In mouse tissue, Lys116 of H1.1 and Lys46 of H1.2 and H1.3 in the spleen were the only sites of ubiquitination. ... list of PTMs that are either absent in MCF7 cells and present in HeLa cells, or present in MCF7 cells but missing in HeLa cells (Table 3). As mentioned earlier, the two...

Ngày tải lên: 18/02/2014, 08:20

... binding of ACP to the docking site followed by a conformational change in ACP proposed to inject the acyl chain into the sub- strate-binding pocket [32]. If a similar mechanism is involved in ... all point to the orientation of H333 and its hydrogen bond donor properties as being the cornerstone of obtaining and ⁄ or retaining residual decarboxylase activity. The emerging picture...

Ngày tải lên: 19/02/2014, 08:20

... FEBS host tyrosine kinases. The phosphorylation triggers a series of interactions between CagA and human proteins that interfere with the signalling cascades at multiple levels, resulting in a dramatic ... presence of Cu(II), the protein shows the presence of the ion coordinated in a small cavity of the surface at the polar opposites of each monomer, close to another dimer pre...

Ngày tải lên: 06/03/2014, 00:21

... 1 c-Actin Actin, cytoplasmic 1 Tubulin b Tubulin a Ankyrin repeat domain-containing protein 18A Ankyrin repeat domain-containing protein 18A Heat-shock protein b1 a-Actin-2 Unclassified Keratin, ... C a-Actinin-2 a-Actinin-3 Desmin VASP Myosin-2 Myosin-3 Myosin-7 (myosin heavy chain 7) Myosin-7 Myosin-9 Myosin-9 Myosin-11 Myosin-13 Myosin-13 Myosin light polypeptide 3 Myosin light polypeptide...

Ngày tải lên: 06/03/2014, 22:21

... September 2009) doi:10.1111/j.1742-4658.2009.07380.x Polypyrimidine tract-binding protein (PTB) is a widely expressed RNA- binding protein with multiple roles in RNA processing, including the splic- ing of alternative exons, mRNA ... Poly- pyrimidine tract-binding protein promotes insulin secretory granule biogenesis. Nat Cell Biol 6, 207–214. 10 Kosinski PA, Laughlin J, Singh K & C...

Ngày tải lên: 07/03/2014, 00:20

... because CHS activity has been reported to increase in response to MeJA together with those of other P450s involved in sanguinarine biosynthesis in EB DA C Fig. 8. MeJA induces the expression of CYP719A2 ... pathway for a variety of isoquinoline alkaloids. (S)-Scoulerine is an intermediate at the branch point leading to benzophe- nanthridine alkaloids in E. californica or berbe...

Ngày tải lên: 07/03/2014, 10:20

... to be involved in locomotor activity in vertebrates inclu- ding the lamprey [41–45]. Therefore, lamprey PQRF- amide peptides may also act in the regulation of locomotor activity. In mammals, in ... of cells expressing lamprey PQRF- amide peptide mRNA in the brain must be taken into account when studying the neuropeptide action. We therefore characterized the regions in th...

Ngày tải lên: 07/03/2014, 12:20

... experiments using crude soluble extract of Escherichia coli containing recombinant stromal APX of spinach [13] and thylakoid-bound APX purified from spinach [5]. These results indicated that an inser- ted ... to lack of binding of the loop to the heme. In contrast to cytosolic APX, whose loop binds noncovalently to a propionate side chain of porphyrin at His239 (Fig. 5A) [14], Ar...

Ngày tải lên: 16/03/2014, 14:20

... cause of HD. Examination o f t he regulation of individual m utant huntingtin-affected genes such as CB1 may increase our understanding of at least o ne abnormal f unction of mutant huntingtin by ... exon 1 of mutant human huntingtin in animals that have a full complement of mouse huntingtin. Transgenic R 6 mouse models differ in the length of the CAG repeat within exon 1...

Ngày tải lên: 16/03/2014, 18:20