báo cáo khoa học: " MicroRNAs involved in neoplastic transformation of liver cancer stem cells" pot

... mechanism of liver cancer stem cells. Conclusions This work provides an in vivo model for the study of mechanisms of neoplastic transformation of liver cancer stem cells by separately sorting SP ... normal somatic stem cells and CS Cs in vitro without the use of stem cell markers. HCC is one of the most malignant tumors in exis- tence. By using SP sorting...

Ngày tải lên: 10/08/2014, 10:20

... characterization of xan- thine dehydrogenase in a baculovirus-insect cell system. In Flavins and Flavoproteins 1993. Proceedings of the 11th International Symposium on Flavins and Flavoproteins (Yagi, ... expression of molybdoenzymes in the xanthine oxidoreductase family. The most important factor involved in producing a functional MPT center in recombinant XDH, using the E....

Ngày tải lên: 16/03/2014, 23:20

... finale manuscript; NB: review of finale manu- script; BEKEG: review of finale manuscript; MI: involved in drafting the manuscript and revising it critically for important intellectual content; SA: ... 76:2497-2503. 14. Buchholz TA, Austin-Seymour MM, Moe RE, Ellis GK, Livingston RB, Pelton JG, et al.: Effect of delay in radiation in the combined modality treatment of breast c...

Ngày tải lên: 09/08/2014, 09:22

... pressure in tumors, enhancing delivery of chemotherapy to t umors [53]. Unfortunately, clinical trials using PDGF-targeting therapy in patients with prostate cancer have been disappointing. Imatinib ... che- motherapy in prostate cancer. Other tyrosine kinase inhibitors are also being considered for use in prostate cancer. For example, AZD2171, also known as cediranib, is an ora...

Ngày tải lên: 10/08/2014, 22:21

... evidences, the role of JCV in human malignancies, and of its oncoproteins in promoting transformation of cells in vitro and in vivo, is still far from clear. J CV does not infect experimental animals, ... interact with proteins involved in cellular regulation such as IRS-1 (Insulin receptor substrate-1), a major protein of the insulin-like growth factor I receptor (IGF-...

Ngày tải lên: 12/08/2014, 04:21

... Y, Dunkel L, Swerdloff RS & Sinha-Hikim AP (2006) Involvement of p38 mitogen-activated protein kinase and inducible nitric oxide synthase in apoptotic signaling of murine and human male germ ... of signal transduction in H 2 O 2 induced tes- ticular germ cell apoptosis. (A) Dose-dependent increase in expres- sion of p53 protein coinciding with (B) a marked rise in transcri...

Ngày tải lên: 16/03/2014, 04:20

... RNA-induced silencing complex; RLC, RNA-induced silencing complex loading complex; RNAi, RNA interference; siRISC, small interfering RNA-containing RNA-induced silencing complex; siRNA, small interfering ... argonaute (AGO)2 loading [46]. Dicer interacts with the dsRNA-binding protein part- ner, the TAR RNA-binding protein (TRBP), in humans [RDE4 in C. elegans and Loquacious (Loqs)inDroso...

Ngày tải lên: 23/03/2014, 06:20

... 0.05). In Pinus radiata high concentrations of auxins and cytokinins were required for early development of the micrograft in vitro. This differed from Sequoia, in which exogenous gibberelin and ... becoming an acceptable methodology for the cloning of several mature species, as Sequoiadendron giganteum [11], Pinus pinaster [4] and Pinus nigra [14]. The practical interest of mic...

Ngày tải lên: 08/08/2014, 14:20

... spermidine, spermine, sarcosine, dimethylglycine, glycine, choline, betaine, a-methyla mino isobutyric acid, methylamine propionnitrile, methyl- amino propylamine. A B Fig. 2. pAO1 genes addressed in ... protein with an N-terminal extension reading MSPIHHHHHHLVPRGS V. The first amino acid of mao is valine (underlined V in the one letter amino acid code). The protein eluted from the nicke...

Ngày tải lên: 19/02/2014, 07:20

... istidine (Fig. 4A,C,D). However, in all C-domains of catalase– peroxidases, there is a conserved arginine (Arg622 in HalomarCPc) in t he corresponding position, indicating that these domains lost ... number of coding seq uences currently in the database may affect this value. Interestingly, none of the known fungal genomic DNA sequences in which KatG is included (listed in T...

Ngày tải lên: 19/02/2014, 16:20