ANEMIAS AND OTHER RED CELL DISORDERS - PART 7 doc
Chapter 027. Aphasia, Memory Loss, and Other Focal Cerebral Disorders (Part 1) pdf
... cognition; an occipitotemporal network for face and object recognition; a limbic network for retentive memory; and a prefrontal network for attention and behavior. The numbers refer to the ... that intersect in Lateral (top) and medial (bottom) views of the cerebral hemispheres. The primary sensory and motor areas constitute 10% of the cerebral cortex. The rest is subsumed ... components. The network approach to higher cerebral function has at least four implications of clinical relevance: (1) a single domain such as language or memory can be disrupted by damage to any...
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Chapter 027. Aphasia, Memory Loss, and Other Focal Cerebral Disorders (Part 4) doc
... Chapter 027. Aphasia, Memory Loss, and Other Focal Cerebral Disorders (Part 4) Gestures and pantomime do not improve communication. The patient ... middle cerebral artery, and to the posterior temporal or angular branches in particular, is the most common etiology (Chap. 3 64). Intracerebral hemorrhage, severe head trauma, or neoplasm are other ... agitation and paranoid behaviors. One area of comprehension that may be preserved is the ability to follow commands aimed at axial musculature. The dissociation between the failure to understand...
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Chapter 027. Aphasia, Memory Loss, and Other Focal Cerebral Disorders (Part 6) doc
... musculature ("close the eyes," "stand up") is subserved by different pathways and may be intact in otherwise severely aphasic and apraxic patients. Patients with lesions of ... of the face and mouth. Limb apraxia encompasses apraxic deficits in movements of the arms and legs. Ideomotor apraxia is almost always caused by lesions in the left hemisphere and is commonly ... pick up a pen and write, the sequence of uncapping the pen, placing the cap at the opposite end, turning the point towards the writing surface, and writing may be disrupted, and the patient...
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Chapter 027. Aphasia, Memory Loss, and Other Focal Cerebral Disorders (Part 7) doc
... specific patterns described in Table 27-1. In a patient Chapter 027. Aphasia, Memory Loss, and Other Focal Cerebral Disorders (Part 7) Gerstmann's Syndrome The combination of acalculia ... Variations of melodic stress and intonation influence the meaning and impact of spoken language. For example, the two statements "He is clever." and "He is clever?" contain ... it is important to establish that the finger and left-right naming deficits are not part of a more generalized anomia and that the patient is not otherwise aphasic. When Gerstmann's syndrome...
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Chapter 027. Aphasia, Memory Loss, and Other Focal Cerebral Disorders (Part 12) doc
... Chapter 027. Aphasia, Memory Loss, and Other Focal Cerebral Disorders (Part 12) The patient with an amnestic state is almost always ... patient is engaged in other tasks. Adequate recall at the end of this interval requires offline storage, retention, and retrieval. Amnestic patients fail this phase of the task and may even forget ... prefrontal, and orbitofrontal components. The terms frontal lobe syndrome and prefrontal cortex refer only to the last three of these four components. These are the parts of the cerebral cortex...
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Chapter 027. Aphasia, Memory Loss, and Other Focal Cerebral Disorders (Part 13) doc
... to another can become impaired. Digit span (which should be seven forward and five reverse) is decreased; the recitation of Chapter 027. Aphasia, Memory Loss, and Other Focal Cerebral Disorders ... initiative, creativity, and curiosity and displays a pervasive emotional blandness and apathy. In the frontal disinhibition syndrome, the patient becomes socially disinhibited and shows severe impairments ... abulia and blandness may be misinterpreted as depression, and the disinhibition as idiopathic mania or acting-out. Appropriate intervention may be delayed while a treatable tumor keeps expanding....
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Chapter 057. Photosensitivity and Other Reactions to Light (Part 7) docx
... Fig. 57-1. Figure 57-1 Chapter 057. Photosensitivity and Other Reactions to Light (Part 7) Porphyria cutanea tarda is the most common type of human porphyria and is associated with decreased ... include an acute photosensitivity characterized by subjective burning and stinging of exposed skin that often An algorithm for the diagnosis of a patient with photosensitivity. Photoprotection ... protoporphyrin helps to differentiate lead poisoning and iron-deficiency anemia, in both of which elevated erythrocyte protoporphyrin levels occur in the absence of cutaneous photosensitivity and of elevated...
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ANEMIAS AND OTHER RED CELL DISORDERS - PART 1 docx
... blood volume and red cell mass: Re-examination of 51 Cr and 12 5I methods. Blood Cells Mol Dis 22 :16 9 18 6.2Greendyke RM. 19 63. Revised normal values for hemoglobin, hematocrit and erythrocytecount ... Reference and selected procedures for the quantitative determination ofhemoglobin in blood; approved standard-third edition. NCCLS document H15-A3 (ISBN 1- 5 623 8-4 2 5-2 ). Wayne, PA: NCCLS CHAPTER 1 PRINCIPLES ... of red cells to determine red cell mass. A sec-ond and more commonly used technique is centrifugation of a blood sample, whichpacks the red cells by centripetal force and leaves the plasma and...
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ANEMIAS AND OTHER RED CELL DISORDERS - PART 3 ppt
... G6PD-deficient ery-throcytes: Possible cause of hemolysis and resistance to malaria. Blood 67 :33 1 33 3.56Roth EF, Jr, Raventos-Suarez C, Rinaldi A, Nagel RL. 19 83. Glucose-6-phosphate dehy-drogenase ... Plasmodium falciparum to glucose 6- phosphate dehydrogenase-deficient host red cells by production of parasite-encoded en-zyme. Nature 31 3:7 93 795. CHAPTER 7 IRON DEFICIENCY 1 03 FIGURE 7–2 Peripheral ... phase of red cell invasion and multiplication. Red cells are constantlycreated and then destroyed as they age and senesce. A mutation that somehow destroysboth the infected red cells and the...
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ANEMIAS AND OTHER RED CELL DISORDERS - PART 4 pot
... ProductionHepcidin - Interleukin 6 - Interleukin 1 TNF-α - Interferon-γ - The cytokines listed are the best characterized to date. Others will undoubtedly be uncovered.TABLE 7-9 KEY DIAGNOSTIC ... stages in red cell development, going from the CFU-E (colony forming unit-erythroid) to the mature erythrocyte. Erythropoietin promotes growth and maturation both of theCFU-E and BFU-E (burst ... H2-receptor antagonists. Med Toxicol Adverse Drug Exp3 :43 0 44 8.59Koop H, Bachem M. 1992. Serum iron, ferritin, and vitamin B12 during prolonged omepra-zole therapy. J Clin Gastroenterol 14: 288–292.60Koop...
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ANEMIAS AND OTHER RED CELL DISORDERS - PART 6 pps
... aplastic anemia: Risk factors and treatment results. Blood73 :60 6 61 3. 16 Tsujimura H, Sakai C, Takagi T. 1999. Pure red cell aplasia complicated by angioim-munoblastic T -cell lymphoma: Humoral factor ... cells/μL reduce the risk of catastrophicbleeds, such as intracranial hemorrhage. PURE RED CELL APLASIAPure red cell aplasia reflects selective destruction of red cell progenitors. Manifes-tations ... myeloblasts and promyelocytesã Few specic granules in metamyelo-cytesã Mixed eosinophilic and basophilic gran-ules in cells at the myelocyte and metamye-locyte stagesã Karyorrhexisã Pseudo-Pelger-Huetcellsã...
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ANEMIAS AND OTHER RED CELL DISORDERS - PART 7 doc
... sideroblastic anemias demon-strate impaired heme production. 78 –80Most commonly, the sideroblastic anemias areclassified as hereditary or acquired conditions (Table 1 2-6 ). The hereditary forms ... the myelodysplastic disorders. 86Hypothermia is a rare antecedentof sideroblastic anemia. 87 In contrast to the hereditary conditions, the acquired sider-oblastic anemias, particularly those ... distribute randomly to the daughter cells. Acquired mitochon-drial defects therefore pass unevenly to the daughter cells.130This property impartsinteresting and unusual attributes to the hereditary...
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ANEMIAS AND OTHER RED CELL DISORDERS - PART 9 ppt
... 20:3341–3346.20Bonkovsky, HL. 199 1. Iron and the liver. Am J Med 301:32–43.21Link G, Konijn AM, Hershko C. 199 9. Cardioprotective effect of alpha-tocopherol, ascor-bate, deferoxamine, and deferiprone: Mitochondrial ... dooms the G6PD-deficient erythrocytes.Heinz bodies also adhere to the red cell membrane where they disrupt architec-ture, promote oxidation and cross-linking of lipids and proteins, and impair ... biophysical and biochemical properties of red cell mem-branes and promote hemolysis. As Figure 1 5-2 shows, glutathione peroxidase defusesH2O2before it can wreck havoc on the cell, a job shared...
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ANEMIAS AND OTHER RED CELL DISORDERS - PART 10 docx
... or red cell sensitization. 10 The drug induces red cell autoantibodies in 10 20% of patients after 4 or more months of use. These red cell antibodies aretrue autoantibodies directed against red ... malaria,87–88sideroblastic anemias, 46, 221acquired sideroblastic anemias vs.hereditary, 223categories of, 223disturbed heme metabolism and, 223drug- and toxin-induced, 228–229inhibits ... 4Antibody 3Endogenous Red CellsTransfused Red CellsAntibody 2LymphNodeAntibody 1NormoblastPacked Red CellsFIGURE 19–1 Schematic representation of the components of immune-mediated hemolysis.Blood...
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Diagnosis and Management of Pituitary Disorders - part 7 docx
... Drug-Eluting Stents for In-Stent RestenosisREALITY Prospective, Randomized, Multi-Center Comparison of the Cypher Sirolimus-Eluting and the Taxus Paclitaxel-Eluting Stent Systems 312 Petersen and ... LosartanELITE-2 CHF 3152 1.5 Yr 15.9% Captopril HR 1.13 [0.95, 1.35] 74 9 (23.8) Mortality 17. 7% Losartan p = 0.016Val-HeFT CHF 5010 2 Yr 19.4% Placebo1 277 (25.5) Mortality 19 .7% ValsartanCHARM CHF 76 01 ... RM. Correlations of plasma lipoproteins with LDL subfractions by particle size in men and women. J Lipid Res 1992;33 :76 5 77 4. 76 . Otvos JD. Measurement of lipoprotein subclass profiles by nuclear...
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