... with APACHE II scores, SOFA scores or C-reactive protein (CRP) levels. Figure 1 Box plots of results in healthy controls and study patientsBox plots of results in healthy controls and study patients. Circulat- ing ... severity of illness as assessed by injury severity score [22], organ failure index [24], Acute Physiology and Chronic Health Evaluation (APACHE) II scores and Se...
Ngày tải lên: 25/10/2012, 10:31
... science of statistics is increasingly employed in all fields of medicine. Statistical techniques are used not only by academics and clinicians directly involved in medical research but also by advocates ... the management of patients have a sound grasp of at least the basics of statistical methods. Unfortunately, in practice this is often not true, with many relying on distant mem...
Ngày tải lên: 25/10/2012, 10:45
Báo cáo y học: "Technical Considerations in Decompressive Craniectomy in the Treatment of Traumatic Brain Injury"
... e d b y loose closure of the dura and skin layers presum a b l y allows for expansion of the edematous brain into a durotomy “bag” under the loosely closed scalp without restriction by the ... Several types of decompressive craniectomy have been performed for the management of trau- matic refractory intracranial hypertension, and the variations in results between studie...
Ngày tải lên: 25/10/2012, 11:40
Báo cáo y học: " Self-reported sickness absence as a risk marker of future disability pension. Prospective findings from the DWECS/DREAM study 1990-2004"
... 154 tervene and potentially prevent early disability pen- sion, we performed analysis for 4174 employees be- tween 18 and 45 years of age at study entry. 2. Methods The study is based upon ... generalizability of the results, and the findings may therefore not apply to the general population. The present study and the study by Gjesdal and Bratberg [10] are to our knowled...
Ngày tải lên: 26/10/2012, 10:03
Báo cáo y học: "Serum cystatin C levels to predict serum concentration of digoxin in Japanese patients
... Introduction Cystatin C (Cys-C) is a non-glycosylated cationic protein of 13.3 kDa, belonging to the cystatin superfamily of cysteine protease inhibitors [1, 2]. Cys-C is produced by all nucleated ... terms of the estimation of pharmacokinetics of drugs. Here, the analysis was Int. J. Med. Sci. 2006, 3 94 Figure 2. Relationships between serum levels of Cys-C and Cr in...
Ngày tải lên: 31/10/2012, 17:08
Tài liệu Báo cáo Y học: CK2btes gene encodes a testis-specific isoform of the regulatory subunit of casein kinase 2 in Drosophila melanogaster potx
... subunits shown in ou r yeast two- hybrid system experiments, it is reasonable to suppose a possibility of a replacement of one b subunit by another i n the case of a deficiency of any of the subunits, ... m M ). Fig. 3. Effect of polylysine on the phosphorylation of calmodulin by catalytic subunit or by holoenzyme reconstituted from CK2a and CK2btes proteins. Calmodulin was phos...
Ngày tải lên: 21/02/2014, 15:20
Tài liệu Báo cáo Y học: Studies into factors contributing to substrate specificity of membrane-bound 3-ketoacyl-CoA synthases pot
... acyl-acyl carrier protein thioesterases and acyl-acyl carrier protein desaturases, a decrease in the activity of the engineered enzymes often resulted, regardless of a high level of identity ... level of activity found in many of the chimeric enzymes. Many of the changes we made resulted in chimeric enzymes with substantially lower activity than the wild-type parents. This w...
Ngày tải lên: 21/02/2014, 15:20
Tài liệu Báo cáo Y học: Interallelic recombination is probably responsible for the occurrence of a new as1-casein variant found in the goat species potx
... (fully), and Ser41 and Ser115 (partly), which originate in proteins with five, six and seven phosphates/mol, explaining the hetero- geneity of phosphorylation observed for the n ative protein by ... Mediterranean a rea usually display a high f requency of ‘strong’ alleles (mainly A and B). However, local and now rare breeds generally do not follow this rule and are often the...
Ngày tải lên: 22/02/2014, 04:20
Báo cáo Y học: O-GalNAc incorporation into a cluster acceptor site of three consecutive threonines Distinct specificity of GalNAc-transferase isoforms pot
... School of Pharmaceutical Sciences, The University of Tokyo, Japan; 2 Department of Oral Diagnostics, Faculty of Health Sciences, School of Dentistry, University of Copenhagen, Denmark O-Glycosylation ... O-glycosylation; mucin; polypeptide N-acetylga- lactosaminyltransferase; Tn antigen; UDP-GalNAc. Biosynthesis of O-glycans is mediated by the step-wise addition of monosacchar...
Ngày tải lên: 17/03/2014, 10:20
Báo cáo Y học: Ligand-induced heterodimerization between the ligand binding domains of the Drosophila ecdysteroid receptor and ultraspiracle docx
... EcR and USP LBD are capable of dimerization in the absence of a bipartite EcRE, and that this protein protein interaction is dramatically enhanced by the presence of ecdysteroids. MATERIALS AND ... greatly enhanced upon adminis- tration of active ecdysteroids in a dose-dependent manner. This was shown in vivo by a yeast two-hybrid system and in vitro by a modified electromobi...
Ngày tải lên: 18/03/2014, 01:20