Association between transforming growth factor b1 polymorphisms and atrial fibrillation in essential hypertensive subjects pptx

... 17:23 http://www.jbiomedsci.com/content/17/1/23 Page 3 of 5 RESEARC H Open Access Association between transforming growth factor b1 polymorphisms and atrial fibrillation in essential hypertensive subjects Yongzheng Wang 1 , Xuwei Hou 2 , ... Li 1* Abstract Background: The association of TGF b1 polymorphisms and atrial fibrillation (AF) in essential...

Ngày tải lên: 10/08/2014, 05:21

... transforming growth factor- b1 (TGF -b1) of the proinflammatory cytokine TNF-a via the induction of FXR1 is the focus of this article. TGF -b1, a member of the large transforming growth factor- b ... FXR1, are known to bind to the ARE in the 3¢-UTR of cytokines, including TNF-a, and regulate translation. We therefore studied the effect of TGF -b1 on RNA-binding proteins, inclu...

Ngày tải lên: 22/03/2014, 21:21

... University of Science and Technology in Wuhan City, Hubei province, China. Participa- tion was voluntary. Detection of mannose-binding lectin gene polymorphisms Polymorphisms in codons 54 and 57 of the ... 4 Research article Lack of association between mannose-binding lectin gene polymorphisms and juvenile idiopathic arthritis in a Han population from the Hubei province o...

Ngày tải lên: 09/08/2014, 08:22

... and p300–C(1571–2370). The intensity of binding, e xpressed as percentage of input bound, is indicated by different shades of gray and only interactions resulting in binding to more th an 1.5% o f input are sh ... Selective DNA binding and association with th e CREB binding protein coactivator contribu te to differential activation of a/b interferon genes by interferon regulatory fact...

Ngày tải lên: 23/03/2014, 13:20

... process. The growth of lymphatic vessels largely depends on many growth factors, such as vascular endothelial growth factor- C and -D (VEGF-C and VEGF-D), platelet derived growth factor- BB (PDGF-BB) and ... counted in all cases ranged between 0 and 4.7. The median value of mean LMVD was 0.5, and defined the cut-off for low and high LMVD. We identified low intratumor...

Ngày tải lên: 09/08/2014, 03:22

... both in experimental models and in humans in which the numbers Review Transforming growth factor- ββ -induced regulatory T cells referee inflammatory and autoimmune diseases Sharon M Wahl 1 and ... involving TGF-β. Treg suppress CD4 + CD25 – responder T cell proliferation and cytokine production, reining in Th1 and/ or Th2 immunity. Without adequate intercession by Treg...

Ngày tải lên: 09/08/2014, 06:22

... trans- forming growth factor- β (TGF-β) signaling in articular cartilage in aging mice [2]. This commentary will discuss TGF-β signaling and osteoarthritis in an experimental investigation in the ... Smad (C-Smad; also known as Smad 4) and inhibitory Smads (Smads 6 and 7). The Commentary Aging, osteoarthritis and transforming growth factor- ββ signaling in cartilage...

Ngày tải lên: 09/08/2014, 07:20

... that in intact G 1 cells (subdiploid cells). For annexin-V/PI staining 1 × 10 6 cells were resuspended in 50 µl binding buffer (Roche Diagnostics, Lewes, UK) and incu- bated with annexin-V/FITC ... activation indices and lymphocyte apoptosis in SLE patients and control individuals were compared using the Mann-Whitney U test. Clinical associations were compared using the Mann-Whi...

Ngày tải lên: 09/08/2014, 08:22

... with and influences the effects of key bone regulators insulin-like growth factor (IGF)1 and transforming growth factor (TGF)-β [93,94] STC1 Stanniocalcin inhibits calcium uptake and has inhibitory ... Finkelman RD, Aerssens J, Baylink DJ: Gen- eralized osteoarthritis associated with increased insulin-like growth factor types I and II and transforming growth fact...

Ngày tải lên: 09/08/2014, 10:21

... immunohistochemistry and toluidine blue staining Scoring of slides from immunohistochemical staining of cell- surface markers, ECM proteins and toluidine blue staining of total proteoglycans was performed blinded ... 2004, 22:1152-1167. 16. Fukumoto T, Sperling JW, Sanyal A, Fitzsimmons JS, Reinholz GG, Conover CA, O'Driscoll SW: Combined effects of insulin-like growth factor- 1...

Ngày tải lên: 09/08/2014, 10:23