Hypoglycemia induced changes in cholinergic receptor expression in the cerebellum of diabetic rats ppt

... mediatedexcitotoxicity in the cerebellum of insulin induced hypogly-cemic and streptozotocin induced diabetic rats [32]. In the present study, we have demonstrated the role of cholinergic receptors during recurrent ... GLUT3 in the cerebellum during insulin induced hypoglycemia in diabetic rats. Altered expression of muscarinic M1, M3 and α7nAchR and increased muscle AchE activity in hypoglycemic rats in cerebellum ... the original work is properly cited.Research Hypoglycemia induced changes in cholinergic receptor expression in the cerebellum of diabetic rats Sherin Antony, Peeyush Kumar T, Jobin Mathew,...

báo cáo hóa học:" Increased androgen receptor expression in serous carcinoma of the ovary is associated with an improved survival" doc

... this study, the prognostic impact of AR expression was investigated using immunohistochemistry in tissue microarrays from 154 incident cases of epithelial ovarian cancer (EOC) in the prospective, ... distribution, and reproduction in any medium, provided the original work is properly cited.ResearchIncreased androgen receptor expression in serous carcinoma of the ovary is associated with ... available at the end of the articleNodin et al. Journal of Ovarian Research 2010, 3:14http://www.ovarianresearch.com/content/3/1/14Page 4 of 6AR expression in relation to survivalAnalysis of the...

Báo cáo khoa học: "Coxsackievirus and adenovirus receptor expression in human endometrial adenocarcinoma: possible clinical implications" doc

... highlightingto the prognostic value of CAR expression in cancer. In this respect, our study is the first report examining the clinical significance of CAR expression in the prognosis of patients ... docking site for Ad, thus acting as a key receptor for the enhancement of the virus-to-host affinityand the initiation of the virus internalization to the hostcell [7,8]. On cells lacking CAR, ... according to CAR positivity (positive vs nega-tive CAR staining), level of expression (high vs low level of CAR expression) and staining intensity (mild vs moderateand intense CAR staining intensity)...

Báo cáo y học: "Nerve growth factor and receptor expression in rheumatoid arthritis and spondyloarthritsi" potx

... blockade of the NGF receptor and their signaling pathway by using receptor antagonists). Our findings prompt further functional as well asclinical studies on the role of neurotrophins and their therapeu-tic ... subsequently the activation of both phospholipase PLCγand protein kinase C, which in turn activates the mitogen-acti-vated protein kinase pathway involving the c-jun N-terminal, the p38, and the extracellular-regulated ... axis in peripheralsynovitis warrants further functional investigation of their activeinvolvement in chronic inflammatory arthritis.IntroductionThere is increasing evidence for the presence of...

Báo cáo y học: "Chemokine receptor expression and functional effects of chemokines on B cells: implication in the pathogenesis of rheumatoid arthritis" ppt

... Each of the four chemokines induced migration of both CD27- and CD27+ B cells (Figure 3a). How-ever, the migration induced by CCL21 was most prominent.Comparison of the migratory effects of ... in the RA syn-ovium [22-29]. Therefore, interactions between the chemok-ines and the chemokine receptors might contribute to B cellmigration into the synovial tissue in patients with RA. In ... aims of thisstudy were to determine chemokine receptor expression by Bcells both in the peripheral blood of normal donors and subjectswith RA, and at the inflammatory site in RA, and the effects...

Báo cáo y học: "Hedgehog overexpression leads to the formation of prostate cancer stem cells with metastatic property irrespective of androgen receptor expression in the mouse model" pps

... 3A;arrow-indicated in (b)), P63 was detected in the cytoplasm of cells in the HGPIN (high grade PIN) lesions (Figure 3A;arrow-indicated in (c)) and CaP (Figure 3A; arrow-indicated in (d)). Interestingly, ... stained strongly for Hedgehogprotein in PIN and CaP, in contrast to those of the sham and vehicle controls. Scale bars: 50 μm in upper (d) of panel A; 10 μm in lower (d) of panel A and in (d) of ... contains the same CMV promoter and the GFP tag, but without the Shh insert. Therefore, presence of GFP in prostatesindicated successful introduction of pCX-shh-IG vectorand expression of Hh protein.Intraprostatic...

Tài liệu Báo cáo khoa học: Lipopolysaccharide-evoked activation of p38 and JNK leads to an increase in ICAM-1 expression in Schwann cells of sciatic nerves ppt

... B of cytokine induced expression of intercellular adhesion molecule 1(ICAM-1) in an intestinal epithelial cell line, a processblocked by proteasome inhibitors. Gut 42, 779–787.23 Lakshminarayanan ... FEBSindicating that LPS induces ICAM-1 expression in SCs, suggest that ICAM-1 may play a role in the focalaccumulation and antigen -induced activation of T cells in inﬂammatory demyelinating ... marker of endothelial cells). In pre-vious studies, ICAM-1–integrin interactions mediatedadhesion of leukocytes to the vascular endothelium,revealing a key role in migration of leukocytes to in ammation...

Tài liệu Báo cáo Y học: Enhancement by a-tocopheryl hemisuccinate of nitric oxide production induced by lypopolysaccharide and interferon-c through the upregulation of protein kinase C in rat vascular smooth muscle cells docx

... that TS induced upregulation of PKCa.DISCUSSION In this study, to obtain information about the mode of actions of TS, we examined the effect of TS on LPS/IFN- induced NO production in VSMC. ... added to the cells, andthen the cell suspension was sonicated in a bath-typesonicator for 5min. The amount of protein of the solubilizedcells was determined with a bicinchoninic acid protein assaykit ... TAand TN inhibited the enhancement by TS of LPS/IFN- induced NO production. The enhancing eﬀect of TS wasobserved in the presence of LPS, but not IFN, suggestingthat TS participates in the LPS-stimulated...

Measuring Changes in Service Costs to Meet the Requirements of the 2002 ppt

... fundamental part of constructing the current-yearexpenditures is to control for any changes in the nature of servicespurchased over time, including changes in the scope of services, and,to the extent ... COSTS The third step is to estimate the cost of purchased services in the following fiscal year. (For the final required report in 2006, the fore-cast is for 2011, five years into the future.) The ... estimate the current-year cost of those services as if they were still purchased, adjusting them by the savings rate achieved by all of the other included services to avoid bi-asing the results....

Báo cáo Y học: Functional expression of human liver cytosolic b-glucosidase in Pichia pastoris Insights into its role in the metabolism of dietary glucosides ppt

... 200220 lL of the enzyme/inhibitor mixture to 180 lLofsubstrate (4NPGlc), incubating for 30 min at 37 °C, andmeasuring the rel ease of 4NP.Protein assays and protein sequencingTotal protein in crude ... rate of 1 mLámin)1 .The following gradients were used: incubations containingarbutin or salicin as substrate; 100% C initial, i ncreasingD t o 2 0% (10 min), 50% ( 15 min), 100% (5 min), held ... oleuropein (olives). The fourth general property of enzymes involved in transformation of xenobiotics isincreased enzyme levels in the presence of xenobioticsubstrates, i.e. inducibility. Cloning the...

Xem thêm

Từ khóa: and an increase in the presentation of the endogenous lectin galectin1 sensing these changes on the surface of p16 ink4a expressing pancreatic carcinoma cells capan1 glutathionylspermidine is an intermediate formed in the biosynthesis of trypanothione we are seeing a global increase in the prevalence of agerelated disorders have been studied as potential key molecules in the pathogenesis of the precancerous intestinal metaplasia of the human stomach however a struggle in the race of life in the orbit of saturn Nghiên cứu sự biến đổi một số cytokin ở bệnh nhân xơ cứng bì hệ thống Báo cáo quy trình mua hàng CT CP Công Nghệ NPV chuyên đề điện xoay chiều theo dạng Nghiên cứu vật liệu biến hóa (metamaterials) hấp thụ sóng điện tử ở vùng tần số THz Giáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôit Phối hợp giữa phòng văn hóa và thông tin với phòng giáo dục và đào tạo trong việc tuyên truyền, giáo dục, vận động xây dựng nông thôn mới huyện thanh thủy, tỉnh phú thọ Phát triển mạng lưới kinh doanh nước sạch tại công ty TNHH một thành viên kinh doanh nước sạch quảng ninh Nghiên cứu về mô hình thống kê học sâu và ứng dụng trong nhận dạng chữ viết tay hạn chế Định tội danh từ thực tiễn huyện Cần Giuộc, tỉnh Long An (Luận văn thạc sĩ)Thơ nôm tứ tuyệt trào phúng hồ xuân hương Thiết kế và chế tạo mô hình biến tần (inverter) cho máy điều hòa không khí Chuong 2 nhận dạng rui ro Tổ chức và hoạt động của Phòng Tư pháp từ thực tiễn tỉnh Phú Thọ (Luận văn thạc sĩ)Quản lý nợ xấu tại Agribank chi nhánh huyện Phù Yên, tỉnh Sơn La (Luận văn thạc sĩ)BT Tieng anh 6 UNIT 2 Tăng trưởng tín dụng hộ sản xuất nông nghiệp tại Ngân hàng Nông nghiệp và Phát triển nông thôn Việt Nam chi nhánh tỉnh Bắc Giang (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vật Giáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vật MÔN TRUYỀN THÔNG MARKETING TÍCH HỢP QUẢN LÝ VÀ TÁI CHẾ NHỰA Ở HOA KỲ