Introduction to Medical Immunology - part 6 ppt
... MHC-II+ macrophages E. RF-producing plasmablasts 21.8 Which one of the following cytokines is usually undetectable in rheumatoid synovial fluid? A. GM-CSF B. IL-2 C. IL-4 D. IL-8 E. Interferon- γ 21.9 ... of vascular hyper- Page 399 21 Rheumatoid Arthritis Jean-Michel Goust I. Introduction Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by inflammatory and deg...
Ngày tải lên: 10/08/2014, 00:21
... have been used to induce tolerance in laboratory animals. It is possible that such peptides are able to bind directly to MHC- II molecules and may deliver tolerogenic signals to T lymphocytes ... anti- idiotypic responses to autoimmunity postulates that autoreactive cells are stimulated by anti-idiotypic antibodies emerging in the wake of an anti-infectious response, due to the...
Ngày tải lên: 10/08/2014, 00:21
... Microbiology and Immunology, Medical University of South Carolina, Charleston, South Carolina Jean-Michel Goust, M.D. Professor of Immunology, Department of Microbiology and Immunology, Medical University ... Education, Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, South Carolina. An-Chuan Wang, Ph.D. Professor, Department of Microbi...
Ngày tải lên: 10/08/2014, 00:21
Introduction to Medical Immunology - part 2 potx
... CD40 ligand (CD40L, CD154, gp39), LFA-1 and ICAM-1. These molecules have counterparts on the APC: CD58 (LFA-3), CD80/ 86, CD40, ICAM-1, and LFA-1 (ICAM-1 and LFA-1 are expressed in both cell populations ... the ability to bind to high- affinity Fc ε receptors) after heating at 56 C for 30 minutes. This binding depends on the tertiary structure of the C- terminal portion of C ε 2 and th...
Ngày tải lên: 10/08/2014, 00:21
Introduction to Medical Immunology - part 3 ppsx
... of 1 2 3 4 5 6 7 8 9 Antibody - - - - + + + + + Antigen + + ± - - - - - - (+ means visible precipitation; - means no visible precipitation) What tube(s) correspond to the antigen excess zone: A. 1 to 3 B. 1 to 4 C. 4 D. 4 to 9 E. 5 to 9 8.2 Using ... stages of CD8-mediated cytotoxicity? A. CD2 : CD58 (LFA-3) B. CD8 : MHC-I C. CD95 (Fas) : Fas li...
Ngày tải lên: 10/08/2014, 00:21
Introduction to Medical Immunology - part 4 pps
... IL-2, interferon- γ , lymphotoxin (TNF- β ), and TNF- α . c. Patients infected by bacteria able to release large amounts of superantigens (e.g., S. aureus- releasing enterotoxins or TSST-1 ... and human T lymphocytes, inducing T-cell proliferation and cytokine release. TSST-1 also appears to activate monocytes and is a potent B-cell mitogen, inducing B-cell proliferation and differen...
Ngày tải lên: 10/08/2014, 00:21
Introduction to Medical Immunology - part 7 pps
... exposure to IgG anti-D antibodies is due to: A. Complement activation B. Fc-mediated phagocytosis C. C3b-mediated phagocytosis D. C3d-mediated phagocytosis E. A combination of Fc and C3b-mediated ... and 25.10 refer to the following case: A 3 6- year-old woman with a history of drug abuse, hepatitis C, and treatment with IFN- γ (6 months prior) presents with recent proven streptococc...
Ngày tải lên: 10/08/2014, 00:21
Introduction to Medical Immunology - part 10 doc
... 470 diagnosis, 269 mechanisms, 420 target tissue, 364 warm antibody type, 46 5-4 66 , 467 case example, 465 , 470 cold agglutinin disease/syndromes, 46 6- 4 67 , 560 cold-induced, 560 drug-induced, 46 7-4 70 Hemolytic ... assays, 30 5-3 06 Mitogens, 305 Mitosis, in CD4+ activation, 19 4-1 95 Mixed-lymphocyte cultures, 519 Mixed-lymphocyte reaction (MLR), 6 4 -6 5, 30 9...
Ngày tải lên: 10/08/2014, 00:21
introduction to medical immunology
... associations of MHC-I and non-self peptides; occupancy of the binding site on the TcR by MHC-I-associated peptide provides the antigen-specific signal that drives cytotoxic T cells. 4. Cytotoxic T lymphocytes ... interaction of CD8 with MHC-I, CD2 with CD58 (LFA-3), LFA-1 with ICAM family members, and CD28 with CD80 and CD 86, to name a few. 6. The expansion of antigen-activated cytotox...
Ngày tải lên: 11/04/2014, 09:48
Vault Career Guide to Investment Banking Part 6 pptx
... company aiming to go public. The S-1 is almost identical to the prospectus sent to potential investors. The SEC must approve the S-1 before the stock can be sold to investors. S-2: A type of ... ratio: The price -to- earnings ratio. This is the ratio of a company’s stock price to its earnings-per-share. The higher the P/E ratio, the more expensive a stock is (and the faster investo...
Ngày tải lên: 02/07/2014, 14:20